An Efficient and Greener Two‐Step Synthesis of Nintedanib: A Scalable Process Development - Chatterjee - 2026 - ChemistrySelect - Wiley Online Library https://t.co/k6sBDarBYH
A quick update ---
Link on YouTube (Technology showcase) : https://t.co/ZMXublPia9
CDRI cases included:
1) Innovative Process for Nintedanib, Dr. Gautam Panda
2) Innovative Process for Centhaquine, Dr. Ajay Kumar Srivastava
3) Innovative Process for Olaparib, Dr. Gautam Panda
To address poor aqueous solubility, Dr. Thakur in collaboration with us prepared new crystalline salts of Nintedanib with hydroxybenzoic acid coformers, nicotinic acid, vanillic acid, p-fluorobenzoic acid etc. https://t.co/GM3GJbcDot
Three variants of our synthesized nintedanib dry powder inhalations (DPIs), one with dibasic calcium phosphate dihydrate (CaHPO4·2H2O) and two with lactose monohydrate as the carrier are obtained and can have significant therapeutic and safety advantages
https://t.co/4wlKBM1LW0
A new kind of bucky-bowl Sumanane and Corannulene derived unnatural amino acids and their peptides have been designed and synthesized. One more publication is derived from my Ph.D. topic which was left nearly 27 years back!!
https://t.co/9sgjrvqiEF
Arpita Banerjee and Indranil Chatterjee successfully defended their doctoral thesis after spending five and half years at CDRI. Good luck to both of them in future endeavors. Both of them worked in Medicinal Chemistry program combined with synthetic organic chemistry methodology.
https://t.co/RW6G5Xa6xy
https://t.co/ZMXublPia9
Innovative CDRI Process for Nintedanib, Centhaquine & Olaparib https://t.co/L0XE0mkzMp Non-binding EOI form: https://t.co/ifUoIS5CIa
Please feel free to ask me any queries who might be interested in our technology
Interested Chemistry students may apply for position code 2-6 to work in a project entitled CSIR (HCP0040) “PAN CSIR CANCER RESEARCH PROGRAM" Tenure upto: 31.03.2026. For details see the attached filehttps://www.cdri.res.in/pdf/recruitment/advt_04_2025.pdf
After a talk on my research topic at IIT and IISER Tirupati on 10th July, I could meet one CDRI Alumni, Dr. Kiran and HCU alumni Dr. Venkaiah and other members there.
It was interesting to interact with students of NIPER, Hyderabad on 1st August, 2024. I could share some of our recent research stories and hurdles with them.
Quite satisfying to publish biomedical application of my Ph.D. topic which was left nearly 25 years back for doctoral studies at HCU, Hyderabad. After I started my career at CDRI in 2002, topic was not pursued by me
https://t.co/Z5fAxTHD38
I was in Hyderabad during 14-19th May, i) To drop daughter Nini ii) To meet Professors at HCU campus, iii) To visit NATCO for collaboration iv) To interact with IICT colleagues v) to visit various places at Hyderabad. Nini will be staying in Le Meridien hotel for two months
I was in IIT Kanpur on 22nd Feb, 2024 along with Dr. Dibyendu Banerjee from CDRI to discuss about possible joint collaborative effort in biomedical research between CDRI and Biological Sciences Div of IIT K
I was in IISER Bhopal on 10th April, 2024 to take Ph.D. viva voce exam of Dr. K. Sreenivas's student, to deliver a talk on amino acids derived NPs and Heterocycles as therapeutic agents. It was very good interaction with chemistry faculties and Dr. Gobardan Das, Director, IISERB.
Stereoselective Construction of 3-(Aminoalkylidene)oxindoles in One Pot: Development of a Novel, Robust, and Scalable Process for the Multigram-Scale Preparation of Nintedanib | Organic Process Research & Development https://t.co/d2UYGbaHGA
Molecular dissection studies of TAC1, a transcription activator of Candida drug resistance genes of the human pathogenic fungus Candida albicans; T Jain, P Mishra, S Kumar, G Panda* D Banerjee*, Front. Microbiol., 12 July 2023, Volume 14 - 2023 | https://t.co/AXl7eMGRvt