Xuecai Ge

Developmental neurobiologist, associate professor at UC Merced

[Xuecai Ge @GeXuecai]

@nishamrafiq Thank you for your notes, Nisha! Nice work on Synaptojanin! Would love to chat about ciliary pocket with you.

[Xuecai Ge @GeXuecai]

@JingHughes Thank you, Jing!

[Xuecai Ge @GeXuecai]

I am excited to share our paper released today in Nature Communications! We found a surprising role for the protein Numb in regulating protein levels in the cilium: https://t.co/o9MtW1Eslk

Congratulations to Dr. Xiaoliang Liu, the postdoctoral fellow in my lab who led this project, and to all co-authors. We are grateful for the invaluable contributions of our collaborators, @Fred_Charron, @JennKong07, as well as the individuals in their labs who participated in this study.

This exciting project began with TurboID from @aliceyting's team, and sheds light on the role of the ciliary pocket in cell signaling and neurodevelopment.

#Cilia #hedgehog #Numb #development #TurboID #CiliaryPocket

[Joseph G. Gleeson @jogleeson_ucsd]

Prof. Xuecai Ge @GeXuecai and Prof. Fred Wolf @flowderf at @ucmerced after a great day in #Merced meeting with students and faculty discussing how our sister institutions can collaborate.

[Joseph G. Gleeson @jogleeson_ucsd]

@GeXuecai thanks so much for hosting me at @ucmerced MCB. Beautiful campus and great students and trainees.

[Xuecai Ge @GeXuecai]

@jogleeson_ucsd @ucmerced Thank you so much for visiting us and for delivering a truly inspiring seminar! We really appreciate your time and the inspiration your provided to our students!

[Joseph G. Gleeson @jogleeson_ucsd]

I'm also excited my visit includes an interview by @radiobio_ucm to discuss biology, from molecules to ecosystems! (https://t.co/kN1HPCwAeV). Thanks for the opportunity to connect with the community!

[Joseph G. Gleeson @jogleeson_ucsd]

Excited to be invited to present lab results at the newest UC today @ucmerced Dept Molecular Cell Biology! https://t.co/lW3BcR1TSw. Thx @GeXuecai for the kind invitation to explore the beautiful campus and meet colleagues!

[Ben Myers Lab @Myers_lab]

Excited to present a new story focusing on how the #GPCR #SMOOTHENED activates GLI transcription factors in the primary cilium during #Hedgehog signaling! Fantastic collab with Radhika Subramanian, @GeXuecai , and many others.

https://t.co/vktp4hZatt

[Xuecai Ge @GeXuecai]

@HariharanLab Really enjoyed the talk and conversations over dinner! Thank you so much for visiting us!

[Iswar Hariharan, ईश्वर हरिहर, ஹரிஹரன் ஈஸ்வரன் @HariharanLab]

Thanks to Nestor Oviedo for inviting and hosting me at UC Merced. Lots of interesting science discussions. Great dinner with Nestor and Xuecai Ge @GeXuecai

[bioRxiv @biorxivpreprint]

Cilium proteomics reveals Numb as a positive regulator of the Hedgehog signaling pathway https://t.co/M51KNThQbH #bioRxiv

[Xuecai Ge @GeXuecai]

Thanks @yiminzounew for visiting UC Merced! The inspirational seminar might have changed the career pathway of many students!

[Ben Myers Lab @Myers_lab]

In the #Hedgehog cascade, the #GPCR #Smoothened signals by physically blocking PKA enzymatic activity. Now out in @NatureSMB! Thanks to all our collaborators, esp. the trainees who worked so hard to bring this story to light during the pandemic! https://t.co/fQzJqFZe7H

[Ben Myers Lab @Myers_lab]

Lastly I want thank our new collaborators @Jingyiz48503151 and @GeXuecai who provided a key primary cilia imaging experiment during the revision. Great job!

[Xuecai Ge @GeXuecai]

@Myers_lab @Jingyiz48503151 Glad to participate in this seminal work! Congratulations!

[Shu-Hsien Sheu @Loom19321]

Happy to share that our work on axon-cilium synapse is now published at Cell😃
https://t.co/vrGQOhmMU9

[Shu-Hsien Sheu @Loom19321]

It didn't get selected, but I had lots of fun making this cover art with my son. Here, the neuron is depicted as an alien (many legs and arms), who receives signals (waves) from his/her antenna (cilium) that changes how he/she thinks (DNA helix). Style inspired by Miró.

[CCBM @CCBM_UCMerced]

Aug 2 - hands-on virtual STEM outreach - "Extracting DNA from Strawberries" - Led by Prof. @GeXuecai, 1-2 pm Pacific - for 5th-8th graders - open to all - free - Register! https://t.co/fk896R6ZV4
#STEM #Biology @ucmerced