Richard Kuo

CEO and Co-founder of Wobble Genomics

Tweets are my own and do not reflect Wobble Genomics.

TAMA creator/developer

[Paolo Tarantino @PTarantinoMD]

ESMO25 & SABCS25 will dramatically reshape breast cancer treatment. We’re preparing an outstanding program for Miami Breast 2026 (March 5-8) to unpack the impact of these upcoming paradigm shifts. Don’t miss it: free registration using the code TARANTINO! https://t.co/MT57htdV1M

[Javier Santoyo @jsantoyo]

How to write a scientific paper in fifteen steps. #ScientificPaper #PaperWriting @PLOSCompBiol
https://t.co/GDMUxaZi5M

[Paolo Tarantino @PTarantinoMD]

SG is a highly effective ADCs, and when used adequately, it saves lives. This includes careful management of toxicities, with prophylaxis when indicated. In this article we review the data & provide RW perspectives on the management of toxicities with SG. https://t.co/ACUZovlVS6

[Kristoffer Sahlin @krsahlin]

Strobealign v0.16.0 has been released. It comes with both runtime and accuracy improvements. Full changelog here https://t.co/79rwhSB3uX

[Andrew Carroll @acarroll_ATG]

Release of DeepVariant 1.8. Large speed improvement (~67% faster) via small model for easy sites. New Pangenome-aware option. Reduces error by ~30% for vg-mapped WGS ~10% for BWA WGS ~5% BWA exome. New config for custom model users, see release notes 1/3
https://t.co/TQmQElqAOR

[AnaConesa @anaconesa]

Do not miss this awesome special issue! Lots of great contributions in LRS #genomics and #trancriptomics

[Richard Kuo @GenomeRIK]

@Magdoll @PacBio This is big news! So that's including the SMRT cell and kits? Sequencing centre cost or actual customer cost?

[BioIndustry Association (BIA) @BIA_UK]

#Genomics is revolutionising how we understand #GeneticMaterial, offering incredible insights into how genes 🧬 function and interact. This session will explore how combining data from multiple #Biological layers—genomics, proteomics, #Metabolomics, and more—is unlocking new breakthroughs💫

✨ Davide Gianni, Senior Director Functional Genomics in Discovery Sciences, #BioPharmaceuticals R&D, @AstraZeneca
✨ Debora Lucarelli, Chief Technology Officer, @tagomics
✨ @perman_jorayev, Ph.D., Investor, @AmadeusCapital
✨ Frances Stocks Allen, Partner, @CooleyLLP
✨@GenomeRIK, CEO, @WobbleGenomics

#TechBio #TechBioUK #biotech

[Richard Kuo @GenomeRIK]

I'll be taking part in a panel discussion at the BIA Techbio event on October 16. Excited for the discussion!

[BioIndustry Association (BIA) @BIA_UK]

At TechBio UK 2024, we're diving deeper into the future of healthcare with our #Genomics Track: 'Beyond genomics – delivering on applications of #Multiomics.' 🚀 ➡ https://t.co/MmxXfoREs2

This session will explore how combining data from multiple #Biological layers—genomics, proteomics, #Metabolomics, and more—is unlocking new breakthroughs. 💫

📌 Davide Gianni, Senior Director Functional Genomics in Discovery Sciences, #BioPharmaceuticals R&D, @AstraZeneca
📌 Debora Lucarelli, Chief Technology Officer, @tagomics
📌 @perman_jorayev, Ph.D., Investor, @AmadeusCapital
📌 Frances Stocks Allen, Partner, @CooleyLLP
📌 @GenomeRIK, CEO, @WobbleGenomics

Special thanks to our headline supporter
@EliLillyandCo and event supporters @ASTRAZENECAUK, @awscloud, @Citeline, @CooleyLLP, @HSBCInnovation, @JNJNews and @lifearc1
👏

#TechBio #TechBioUK #Biotech

[Richard Kuo @GenomeRIK]

@anaconesa @FJPardoPalacios @dlfuente_lorena @Magdoll @manueltard @LaurenMMcIntyr1 Congratulations!!

[The Nobel Prize @NobelPrize]

This year’s medicine laureates Victor Ambros and Gary Ruvkun studied a relatively unassuming 1 mm long roundworm, C. elegans.

Despite its small size, C. elegans possesses many specialised cell types such as nerve and muscle cells also found in larger, more complex animals, making it a useful model for investigating how tissues develop and mature in multicellular organisms.

Read how the 2024 medicine laureates’ investigations into C. elegans revealed an entirely new dimension to gene regulation: https://t.co/8RwUplwYQA

#NobelPrize

[The Nobel Prize @NobelPrize]

BREAKING NEWS
The 2024 #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun for the discovery of microRNA and its role in post-transcriptional gene regulation.

[AnaConesa @anaconesa]

Today I will be speaking at the @NeuroAlc, hosted by Prof @NietoAngela @BCBHubCSIC @CSICval @i2sysbio

[Richard Kuo @GenomeRIK]

@coregenomics @ambulanzen I'm also struggling with this. Feels like the scientific community just scattered and now there isn't a unified place to communicate. I'm not sure boycotting the platform has done anything other than make it harder for the community to share ideas.

[AnaConesa @anaconesa]

At #ECCB2024? Do not miss the highlight talk presentation of @Conesa_Lab member Alejandro Paniagua about our @ELIXIREurope tool #SQANTI3, at 10:15 h at Teatro Room. @HiTSeq @PacBio @nanopore @LongtrecEU @i2sysbio @BCBHubCSIC . Thanks to @CSIC INFRAS2024 for travel support!

[Erik Garrison @erikgarrison]

making a lot of pairwise alignments (PAF) and needed a way to confirm validity of both coordinates and alignment https://t.co/zxFF7P6mLK

[Rosemary Sinclair Dokos @RosemaryDokos]

Super exciting to see what the future holds for nanopore beyond DNA and RNA sequencing https://t.co/7kCQlfhh0g

[Liz Tseng @Magdoll]

Sebra: @PacBio Iso-Seq in pre-implantation embryo find novel isoforms rich in antisense and intergenic. Conserved in primates, suggesting driving recent evolution.

https://t.co/hp7kARBhM0

[Liz Tseng @Magdoll]

Use of 26 @PacBio Iso-Seq cell line data to build a RNA foundation model LoRNA to predict transcriptome architecture, including isoform abundance, exonic structures, and variant pathogenicity. #bioinformatics

https://t.co/yBETpvOFyq

[Liz Tseng @Magdoll]

We've updated the @PacBio Kinnex single-cell RNA SMRT Link v13.1 troubleshooting guide to cover what are the metrics you should expect and how to analyze not officially tested kits such as GEM-X. #bioinformatics

https://t.co/LCugcJHrRu