Geoff Bellini MD

Board Certified Surgical Oncologist, Associate Program Director, Dad, Husband and NY Rangers Fan

[JAMA Surgery @JAMASurgery]

Body composition scores reflecting the quantity and quality of skeletal muscle were strongly correlated with patient frailty and associated with 30-day readmission and postop mortality and morbidity. https://t.co/RYxbgQrzLT

[Annals of Oncology @Annals_Oncology]

New article in press: Total neoadjuvant therapy with mFOLFIRINOX versus preoperative chemoradiotherapy in patients with locally advanced rectal cancer: long-term results of the UNICANCER-PRODIGE 23 trial. @GroupeUnicancer @icl_lorraine
https://t.co/DlPjBhLzGb

[Surgical Oncology Insight @SurgOncInsight]

RAS mutation is an independent predictor of poor prognosis for CRLM. Especially in patients with RAS mutations, surgical margin (SM) <2 mm is associated with significantly worse post-hepatectomy DFS, suggesting achieving a wider SM (≥2 mm) is indicated.

https://t.co/nYPu61EJqb

[E60 @E60]

30 years ago, down 3-2 in the Eastern Conference Final, Mark Messier guaranteed a Rangers win…and delivered. Facing the same situation tonight, what will happen?

‘No Easy Victories’ premieres this Tuesday at 9 PM ET on ESPN.

[Mike Thompson, MD, PhD, FASCO @mtmdphd]

Oncology precision medicine for hepatobiliary and pancreatic cancer: Insights and updates from a large community health system [Jan 24, 2020] @GeoffBelliniMD et al. #GI20 J Clin Oncol 38, 2020 (suppl 4; abstr 570) https://t.co/AjNEt6gJMN #hpbcsm #PrecisionMedicine

[JAMA Surgery @JAMASurgery]

Most viewed in the last 7 days from @JAMASurgery:

Can preoperative computed tomography scans provide patient frailty assessments that are associated with outcomes of abdominal surgery?

https://t.co/4KEp4ArJ2s

[JAMA Surgery @JAMASurgery]

Study found that approximately half of patients with locoregionally advanced cutaneous squamous cell carcinoma had a favorable response to preoperative immunotherapy, and clinical responders sometimes opted to forgo planned surgery. https://t.co/tCsv6NuxNp

[JAMA Surgery @JAMASurgery]

Double-blinded MOBILE2-trial found that mechanical bowel preparation and oral antibiotics reduced the rate of overall morbidity, surgical site infections and anastomotic leaks compared to mechanical bowel preparation only prior anterior rectal resection. https://t.co/1mVNqwWmMx

[BJS @BJSurgery]

Survival and safety after neoadjuvant chemotherapy or upfront surgery for locally advanced colon cancer: meta-analysis
➡️ https://t.co/JN4Ga415Jg

This systematic review and meta-analysis of seven studies involving 2120 patients with locally advanced colon cancer found that neoadjuvant chemotherapy is associated with a reduced hazard of recurrence and death, as well as improved 5-year overall survival and disease-free survival rates, compared with upfront surgery. No significant differences in perioperative complications or mortality were found, but neoadjuvant chemotherapy decreased the risk of incomplete resection.
In conclusion, neoadjuvant chemotherapy appears to offer oncological benefits in the treatment of locally advanced colon cancer.

Great work by @ClinicaNavarra - Daniel Aliseda, Jorge Arredondo, Carlos Sánchez-Justicia, Alicia Alvarellos, Javier Rodríguez, Ignacio Matos, Fernando Rotellar, Jorge Baixauli, Carlos Pastor

#SoMe4Surgery #MedTwitter #SurgEd #Surgery @RCPSGTrainees @aecirujanos @SEIQuirurgica @iss_sic #MedicalTechniques @BJSAcademy @young_bjs @BJSOpen @des_winter @evanscolorectal @robhinchliffe1 @bplwijn @ksoreide @MalinASund @nfmkok @TejedorPat @paulo_sutt @PVaughanShaw @JJEarnshaw @juliomayol #colorectalsurgery #StepUp4CRC @FightCRC @ACPGBI @Dukes_Club@ACPGBI_EduTrain@escp_tweets @YouESCP

[BJS @BJSurgery]

Reinforcement of the stapled duodenal stump during laparoscopic gastrectomy
➡️ https://t.co/QrMlTPpVHq

Duodenal stump leakage can be reduced by reinforcing the duodenal stump. In a recent study, including 965 patients, the duodenal stump leak rate was 0.7% in the reinforcement group versus 5.7% with no reinforcement (P < 0.001).
Moreover, fewer patients underwent surgical re-exploration in the reinforcement group, suggesting that the leak was less severe. Burying the staple line of the duodenal stump using a seromuscular suture may prevent a leak from any vulnerable point caused by poor stapling, or from becoming a clinically relevant leak causing abdominal infection and septic bleeding.
Additionally, burying the staple may reduce the pressure on the staple line from the inside.

Great work by Wenwu Liu, Xiaojiang Chen, Zhiwei Zhou, Yongming Chen

#some4UGI #uppergi #esophagealcancer #gastriccancer #reflux @ISDE_net @Augishealth @roux_group @T4UGIS @SARONG_Trial #SoMe4Surgery#MedTwitter#SurgEd#Surgery@RCPSGTrainees@aecirujanos @SEIQuirurgica @iss_sic

[Aurora Health Care Surgical Oncology Fellowship @AuroraSurgOnc]

We are very proud of Rebecca Kirschner, our 2nd year CGSO fellow for earning the opportunity to present her complex case at the SSO Fellows Institute. Nice job!
#sso #advocatehealth @RcKSurgeon @AuroraSurgOnc

[Laleh Melstrom @laleh_melstrom]

Randomized Controlled Trial of Perioperative Telemonitoring of Patient Generated Health Data in Gastrointestinal Oncologic Surgery ⁦@MustafaRaoofMD⁩ ⁦@SoCalYuman⁩ ⁦@AndreasMKaiser⁩ ⁦@KristenLimbach⁩ ⁦@VirginiaSunPhD⁩ https://t.co/5Mz0af1lqU

[Giovanni Marchegiani @Gio_Marchegiani]

Predict Pancreatic Fistula 🐳 using only preoperative data and Machine Learning 🤖

🇺🇸 ACS-NQIP @AmCollSurgeons 9k whipples

4 models identified 🔝 predictors as BMI, 🤏 small duct, NO chemo / adenocarcinoma

👏 Great tool, when would you apply it ?! 🧐

https://t.co/wN2ETyOIR8

[Annals of Surgical Oncology @AnnSurgOncol]

PUBLISHED: #CirculatingTumorCells are an Independent Risk Factor for Poor Prognosis in Patients with #GallbladderAdenocarcinoma. https://t.co/yelqnCIMBC @SocSurgOnc

[Annals of Surgical Oncology @AnnSurgOncol]

PUBLISHED: Prognostic Significance of #SentinelLymphNode Status in #ThickPrimaryMelanomas. https://t.co/lJP4lsUmvd

[Annals of Surgical Oncology @AnnSurgOncol]

#VisualAbstract : Impact of #PrimaryTumorLocation and #GenomicAlterations on Survival Following #CytoreductiveSurgery and Hyperthermic Intraperitoneal #Chemoperfusion for Colorectal Peritoneal Metastases

https://t.co/auEj4H1s25

[Annals of Surgical Oncology @AnnSurgOncol]

ASO Paper in 60 Seconds: Circulating Tumor DNA as a Prognostic Marker in Borderline-Resectable #PancreaticCancer . #ASOin60seconds
@rajarnarayan https://t.co/OZoGT0B9fr

[Mike Pishvaian @MPishvaian]

Hmmm....well.....that was unexpected

Dr. Labori presented a well run, straightforward randomized Ph2 trial comparing Pre-Op FOLFIRINOX vs Upfront surgery for resectable #pancreaticcancer

[Flavio G Rocha, MD, FACS, FSSO @FlavioRochaMD]

Yield of diagnostic laparoscopy with washings for #PDAC is 21% in era of modern imaging leading to change in 🦀 management in 1/5 of 1K pts 👏 authors @PancreasClub

Conclusion: DL should be done ideally prior to neoadjuvant chemotherapy

How to incorporate into clinical trials?

[New York Rangers @NYRangers]

IT'S SHOWTIME ON BROADWAY.