Gerry Santtiago GS

🔴 Hematologist 🩸 Interested in Lymphoma

[Gerry Santtiago GS @GerryGS3]

#LaFinaldelaObsesion
#pumas
#CU

[Henry C Fung| MM, lymphoma, leukemia & CART @HenrychihangFu1]

Not all MYC lymphomas are Burkitt.

A simple way to approach high-grade B-cell lymphoma:

1. High Ki-67 → suspect aggressive lymphoma
2. Check MYC (FISH)

If MYC rearranged:
→ Check BCL2

• BCL2 negative → Burkitt lymphoma
• BCL2 positive → Double Hit lymphoma

If MYC not rearranged:
→ DLBCL / other HGBCL

Key rule:
BCL2 positivity excludes classic Burkitt lymphoma

Morphology helps:
Burkitt = homogeneous, intermediate-sized cells
Double Hit = heterogeneous, pleomorphic

Genetics defines biology.

#Lymphoma #Hemetwitter

[Gerry Santtiago GS @GerryGS3]

@plasmablasto @SRE_mx @m_ebrard JAJAJA 😎

[Yash @DoctorBhavsar]

💊 Clopidogrel has a half-life of about 6–8 hours, the why to stop it 5 days before surgery ? 🤔💭

#Clopidogrel #Preop #InternalMed #MedX

[Nikolas Spyrou @NikolaSpyrouMD]

Azacytidine, our fantastic hypomethylating agent, used for treatment of MDS and AML, was discovered in 1964, and then fell into oblivion. Almost 40 years later it was FDA approved as the first effective MDS treatment.

A 🧵about an unusual revival:

[Raj Chakraborty @rajshekharucms]

🧵 1/6 Now online @BloodPortfolio: Time to revise/re-evaluate #Myeloma Diagnostic Criteria? @ManniMD1 and I make an argument that sFLC ratio≥100 should not be used as a standalone criterion due to the risk of systematic overdiagnosis and overtreatment!
(Figure below shows that this is a heterogeneous group with a vast majority having a low risk of progression to CRAB MM)
https://t.co/JshuBxmNKB

[Gerry Santtiago GS @GerryGS3]

The patient persisted asymptomatic. Further studies were performed HTLV 1 and 2 negative. Euro-flow: Mature T lymphocytes 83% with asynchrony in maturation, expression of: CD99+ CD2+, CD5+, CD7+, CD45RA+ CD3c+ CD3m+, CD44+, CD8+, CD10- CD56-, CD117-, CD4-, CD33- (4/5)

[Gerry Santtiago GS @GerryGS3]

Peripheral blood smear shown mature and small lymphocytes without blebs or atypical forms. CT scan was normal, a Bone marrow biopsy was performed with the same morphology of small and mature lymphocytes CD3+, CD5+, CD8+ CD7+++ with conclusion of a PTCL-NOS CD8+. (3/5)

[Gerry Santtiago GS @GerryGS3]

@joshuanbarbozam Para inscribirme ?

[Gerry Santtiago GS @GerryGS3]

@DrChavezDiaz Cada quien responde acorde a sus experiencias. En mi caso, Doctoralia me ha ayudado mucho. A la fecha tiene distintos formatos y formas de pago; existen muchos factores tales como lugar de consultorio (competencia), días de consulta. A mi, si me ha ayudado mucho 👍🏼

[Gerry Santtiago GS @GerryGS3]

@iamtanmoy24 What is your mother's treatment protocol?

[Gerry Santtiago GS @GerryGS3]

@Ellenore_YFNTC @Hotlegs101_art @ValidHazelTrans How was your treatment?

[Gerry Santtiago GS @GerryGS3]

@JulioFdez79 Historia de fármacos en tuberculosis 🫡

[Talha Badar @TalhaBadarMD]

#Weekend_review 🧵 #IMresident #hemoncfellows
1/10 JAK2 unmutated or non-PV erythrocytosis or idiopathic erythrocytosis

Not every polycythemia/erythrocytosis is polycythemia vera (PV)!

JAK2 unmutated or non-PV erythrocytosis: hereditary and acquired.

Up to 70% of cases, erythrocytosis remain uncharacterized “idiopathic”

[Gerry Santtiago GS @GerryGS3]

@alex_epi_tria Yep. Mexico city

[Gerry Santtiago GS @GerryGS3]

first Mexican patient to receive Glofitamab

#Glofitamab.
#DLBCL

[Gerry Santtiago GS @GerryGS3]

@hematologo Sesión #AbbVie
DLBCL

[𝗡𝗶𝗵𝗮𝗿 𝗗𝗲𝘀𝗮𝗶 MD, DM @nihardesai7]

Hey #NEETPG aspirants 👋🏻 This one's for you !!

Red cell inclusions:

•Howell-Jolly bodies = DNA remnants
•Basophilic stippling = RNA remnants
•Pappenheimer bodies = Iron
•Cabot rings = Mitotic spindles
•Heinz bodies = denatured Hb

Now tell me, what's 👇🏼

#MedTwitter

[Thrombosis Update @ThrombUpdate]

New article alert:
Anticoagulant prophylaxis in pregnant women with a history of venous thromboembolism: A systematic review and meta-analysis
https://t.co/ekBOnwf5Tn

@ELShematology @ThrombUpdate @LucyNORTCD