📢 What is the relationship between polygenic risk and individual symptoms of psychopathology? In a new pre-print (and my first PhD study!) we combine network analysis and polygenic risk scores ⬇️ https://t.co/555jseTouQ [1/9]
Just out in @NatureHumBehav
👇🏼👇🏼
We focused on the causes & impact of self-report error in the UK Biobank. We found that reporting error does not occur at random, is not independent of other participation behaviours, and can complicate the interpretation of genome-wide findings
We have a new preprint out examining symptom-specific polygenic effects on maternal mental health during pregnancy and postpartum in up to 59,000 MoBa mothers 🧬🌧️☀️
https://t.co/m5evQYSwrb
@Psykologiskinst@PromentaC@PsychGenNIPH
Excellent blog by @GiuliaPiazza15 & @jonroiser for @mental_elf on our paper on depressive symptom dynamics and the need to improve clinical characterisation of mental disorders by taking into account their dynamic nature & the disorder evolution over time
https://t.co/Gwf9VgIuUF
enjoyed writing this blog with @GiuliaPiazza15 on a recent study describing individal symptom networks in depression @AndreaCipriani@OmidVEbrahimi. Will be interesting to see how this develops and whether network structure is associated with response to interventions!
Is my depression the same as your depression? Network analysis finds individual variation in how symptoms aggravate each other over time https://t.co/sc8yaPH0Q6
Great blog by @GiuliaPiazza15 & @jonroiser on excellent study by @OmidVEbrahimi et al in @TheBJPsych
In a 3 cohort and 3 measure replication (ALSPAC @CO90s, #ABCDstudy, MCS @CLScohorts) we found:
1. Network temperature 'cooling' across adolescence indicating ⬆️ network stability and ⬇️ symptom variability (more alignment) with age ❄️
[5/9]
🚨🌡️New pre-print on PsyArXiv!
We conceptualise and investigate network temperature as a measure of longitudinal stability in depression symptom networks across adolescence...
https://t.co/N2vfmM2wKb [1/9]
Pre-doc RA job in our NMH lab at @UCL_ICN with @olijrobinson! Focusing on mechanisms of treatment in anxiety, a great opportunity to learn skills in mental health/neuroscience/computational research and work in a collaborative environment, deadline Aug 7th https://t.co/hiu6xphIEl
Grateful to be invited to share my thoughts on research culture by the team at @KingsIoPPN (those who know me, know I have many)
https://t.co/WvNkTASNqZ
Which specific mental health symptoms are associated with genetic risk? Answers in our new Jama Psychiatry paper led by @GiuliaPiazza15 in n=5521 with preregistered replication in n=4625.
https://t.co/1glPu7u3bJ
JOB ALERT: We're advertising for a ~1-year Research Assistant on the @The_MRC funded ReThink project. @UCLPALS
Ideal for those interested in child trauma, mental health and wellbeing. Qualitative or mixed-methods experience ideal.
Link below:
https://t.co/YYftJnK2Pz
Combining networks and polygenic scores, this study shows polygenic scores for psychopathology traits associate with a restricted number of trait-relevant and cross-trait symptoms, replicated in an independent sample with preregistered analyses. https://t.co/f9mufkC6X0