Gregory Madden, MD

Father of Amazing Twins, Infectious Diseases Specialist, Fisherman, Lover of Puns and Science.

[UVA ID @UVA_ID]

Congratulations to UVA ID’s Dr. @costisifri and all the other awardees!

[Dr. Glaucomflecken @DGlaucomflecken]

Hanging out with the infectious disease specialist

[Gregory Madden, MD @GregoryRMadden]

C. difficile burden predicts increased hospital cost, but not in the way we expected! High cycle threshold PCR positives (as marker of colonization) may be costlier than “true” infections. 1 more good reason for diagnostic stewardship :) https://t.co/MmzCXeJ6ao @GIDIuva @UVA_ID

[Gregory Madden, MD @GregoryRMadden]

Good article, even better title! We should not abandon the tenets of good medicine, even in a pandemic. https://t.co/4bdesiW5vr

[Gregory Madden, MD @GregoryRMadden]

Interesting observation: COVID-19 in Virginia appears to be hitting hardest in cities where mobility returned quickly to baseline (i.e. VA Beach, Norfolk), but so much the case in rural areas (i.e. Shenandoah Valley). @UVA_ID

[Gregory Madden, MD @GregoryRMadden]

Congrats to @joesph_wiencek @andrewparsonsMD @costisifri for their excellent summary and analysis of COVID-19 antibody testing @UVA_ID ! Let's stick to the guidelines.
P.S. I'm loving the bubble plot : ) https://t.co/hxMn28Ver9

[Gregory Madden, MD @GregoryRMadden]

Noticing a disturbing VA COVID-19 trend focused in the tidewater area, perhaps hastened by July 4 weekend (~4-5d incubation)/summer vaca? Any other thoughts why this area in particular? @UVA_ID

[Gregory Madden, MD @GregoryRMadden]

These are the latest data from VDH by health district. Test positivity in Loudoun has nearly doubled in the past week. Similarly concerning trends in Richmond, Piedmont...all despite increased testing.

[Costi Sifri, MD @costisifri]

#COVID19 test positivity is climbing in much of #Virginia despite increased testing. Cases, test positivity and hospitalizations are climbing in most areas of the US outside the NE corridor. It's time to learn from those who moved too fast - #Pause Phase 3 now. #cville #roanoke

[Gregory Madden, MD @GregoryRMadden]

@UVA_ID @UvaDOM @uvahealthnews Thanks Chris! I am honored to be joining the ranks of my ID role models : )

[Gregory Madden, MD @GregoryRMadden]

Will a PET/CT be easier to get than a TEE?

[David Paterson @davidantibiotic]

Changing the management of Staph aureus BSI. Impact of PET/CT on the management of patients suspected of infective endocarditis: the prospective multicenter TEPvENDO study https://t.co/e9yE28gMP5

[Gregory Madden, MD @GregoryRMadden]

Ah thanks! Updated link https://t.co/hSjWJvTPQP

[Costi Sifri, MD @costisifri]

Congratulations @GregoryRMadden. However, this is the link to the poster abstract presented at #IDWeek. Fortunately the paper is out now #OFID :)

[Gregory Madden, MD @GregoryRMadden]

Hot off the presses! A deeper dive into patient outcomes with C. diff decision support, including “prevented” tests. Many thanks to my co-authors⁩ ⁦@costisifri⁩ ⁦@KBEnfieldMD⁩ and the C. diff coalition for their strong work! ⁦@UVA_ID https://t.co/qGHEf4Ze6d

[Gregory Madden, MD @GregoryRMadden]

Scary stuff but relevant for contact tracing; 44% of secondary COVID-19 infections occur before the index case is symptomatic! https://t.co/EGMKJDku63

[Gregory Madden, MD @GregoryRMadden]

Who would’ve thought Anthony Fauci would have been the topic of an SNL cold open, and played by Brad Pitt! P.S. don’t inject disinfectant. https://t.co/DrqfcTG1RZ

[Gregory Madden, MD @GregoryRMadden]

@PEHJackson Props to whoever built the PVC pipe racks!

[Gregory Madden, MD @GregoryRMadden]

Considering the reports of significant cardiac toxicity, availability issues, should we abandon broad use of HCQ for COVID?

[Paul Sax @PaulSaxMD]

Pre-print RCT of HCQ vs SOC. N=150, mild dz, young.
- No antiviral efficacy (primary endpoint)
- Possible resolution of symptoms faster in small subset w/ no other antiviral therapy
- CRP down more
Seems more an anti-inflammatory than an antiviral
https://t.co/tNBdmFNWYh

[Dr. Taison Bell @TaisonBell]

Plaquenil may work for #COVID19 or it may not. What is definitely does is hurt (even kill) some people. It’s a small percentage thankfully, but it means that we need to carefully study it before peddling it to the public. Politics need to remain out of the scientific process

[Ben Hunt @EpsilonTheory]

Must read. This is INSANE.

“Since the patient did not fit the existing CDC criteria for COVID-19, a test was not immediately administered.”

[Gregory Madden, MD @GregoryRMadden]

A curious case of prosthetic joint infection in a dog breeder and heart transplant recipient due to Anaerobiospirillum, an unusual spiral-shaped bacterium found in the canine GI tract. https://t.co/A2rFjlNcjm @UVA_ID

[Gregory Madden, MD @GregoryRMadden]

Babies’ first polo match! 🐎 @ King Family Vineyards https://t.co/7bbv8mqEwC