Morning everyone, very excited to say our PNAS paper was published online yesterday. 🥳 It’s been a while coming and is the work of my PhD so great to see it finally out there.
https://t.co/rQuO0QP9CY
Haven’t posted for a while but thought I’d use my network on here to promote. Maya is 12 years old with neuroblastoma. She’s the daughter of a friend and is having a particularly hard time currently so any support you can show for a little boost would be amazing! Thank you ☺️
Morning everyone, very excited to say our PNAS paper was published online yesterday. 🥳 It’s been a while coming and is the work of my PhD so great to see it finally out there.
https://t.co/rQuO0QP9CY
We use DNA-based tension sensors on model membranes to control antigen valency and mobility. Using these tools, we see that low antigen mobility increases the probability and speed of antigen extraction while also improving affinity discrimination. Something I find very exciting!
B cells are mechanoresponsive and in this beautiful work @HCW_McArthur shows how antigen mobility regulates both the dynamics and precision of antigen capture at immune synapse by B cells 🧬🔬🐭 Check it out! 👁️
So today has been a big day, not only did we submit our paper but I also passed my viva with minor corrections! Thank you so much to everyone for your help along the way - couldn’t have done it without you all. Thank you to Martin Lowe and @paolo_pierobon for a great discussion!
I’m really happy to present our latest @biorxivpreprint: “Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse” led by @HCW_McArthur with contributions from @MaroIliopoulou and @AnnaBajur. Check it out!
https://t.co/NBApyBHuxw
@AnnaBajur@paolo_pierobon Thank you, it’s been an absolute honour to work alongside you also. Couldn’t have done it without you, both professionally and personally!
I’m really happy to present our latest @biorxivpreprint: “Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse” led by @HCW_McArthur with contributions from @MaroIliopoulou and @AnnaBajur. Check it out!
https://t.co/NBApyBHuxw
Awesome and inspiring presentation from @katelynspillane on how membrane viscosity of APCs impact B cell antigen internalization! Amazing my dear! #LARSW#immunology#Bcells
Happy to share our methods chapter on quantifying force-mediated antigen extraction in the B cell immune synapse 🧬 🔬 @HCW_McArthur@katelynspillane : https://t.co/X8zRoDDhXL
Haven’t posted for a long time as I’ve been busy looking after my baby girl but I’m excited to share our new methods chapter, where we detail how to quantify force-mediated antigen extraction in the B cell immune synapse using DNA-based tension sensors. https://t.co/wSmO535v4l
I am raising morning for Cancer Research UK by running 60 miles in September! I great excuse to get back in the running and keep at it!
Please donate!
#cancer#childhoodcancer#braintumour https://t.co/su1W8ufMLG
here's a digital copy of my ABCs book of protein structure and function (used as a children's book for outreach). recently submitted to the inaugural @ibbgatec art show <3.
https://t.co/Wv0a5RfRVG