pleb drea

Resarcher

[Kevin McKernan @Kevin_McKernan]

I don’t post about the labs in the w$r zones as it leads to deplatforming.

Russia probably cares much more about a Plum island in their backyard than some penis piano playing puppet laundering USD for swamp creatures.

[Nicolas Hulscher, MPH @NicHulscher]

Our peer-reviewed autopsy study reports a previously healthy 47-year-old man who died suddenly from a massive pulmonary hemorrhage 555 days after a Pfizer shot.

Kyle Busch's death appears eerily similar to this case.

From hoarseness and cough to catastrophic hemorrhage — the rapid cascade killing healthy men is gravely concerning.

[Nicolas Hulscher, MPH @NicHulscher]

CDC DATA SHOW COVID SHOTS TRIGGERED 146 NEUROLOGICAL & PSYCHIATRIC SAFETY SIGNALS

Over 70% of humanity underwent a chemical lobotomy masquerading as “vaccination.”

This explains the widespread collapse of common sense, deterioration of cognitive function, and drastic personality distortions seen since 2021.

Safety signals identified in our two peer-reviewed studies include:

📈PRION DISEASE — 847× more likely vs. flu shot

📈BRAIN CLOTS — 3,000× more likely

📈PSYCHOSIS — 440× more likely

📈HOMICIDAL IDEATION — 25× more likely

📈DEMENTIA — 140× more likely

📈SUICIDAL THOUGHTS — 150× more likely

📈SCHIZOPHRENIA — 315× more likely

📈DEPRESSION — 530× more likely

📈HERPES ZOSTER MENINGITIS — 1,200× more likely

📈TOXIC ENCEPHALOPATHY — 157× more likely

📈MENINGITIS (ALL TYPES) — 34× more likely

📈AUTOIMMUNE ENCEPHALITIS — 79× more likely

📈BRAIN ABSCESS — 120× more likely

📈SPINAL CORD ABSCESS — 89× more likely

📈VIOLENT BEHAVIOR — 80× more likely

📈COGNITIVE DECLINE — 115× more likely

📈DELUSIONS — 50× more likely

📈 MYELITIS (ALL TYPES) — 31× more likely

And many more......

The mRNA shots disrupt the blood–brain barrier, allowing mRNA, amyloidogenic spike proteins, and pathogens to penetrate the brain and spinal cord — an outcome consistent with the skyrocketing rates of cognitive decline now seen across the world.

[Kevin W. McCairn PhD @KevinMcCairnPhD]

@eitchan Augmented NAC is a scam product, that does nothing for the underlying amyloidogenic pathaology.

[Jacqueline Lord @iamjaclord]

@BasedBiohacker There’s new research linking augmented NAC to tau in the brain.

[BIG 77 @BBSchizo777]

Wellness, great division

[MECFS, MCAS and PTSD @FatigueMe92484]

In my model, I suggest there are many conditions that downregulate the glucocorticoid receptor ( ie. glucocorticoid resistance via childhood trauma or sleep deprivation). What happens when the glucocorticoid receptor is downregulated? In normal circumstances there is a GR- orexin- stimulating norepinephrine axis?

When glucocorticoid receptors (GR) are downregulated, the brain loses its primary off-switch for the body's stress response. This structural deficit leads to a condition known as glucocorticoid resistance, causing the [hypothalamic-pituitary-adrenal (HPA) axis](https://t.co/r5KITx6UVd) to become hyperactive, unchecked, and chronically locked in a survival state. [1, 2]
Based on the orexin-norepinephrine-GR circuit discussed previously, GR downregulation triggers several distinct neurobiological consequences:
## 1. Chronic Hyper-Arousal and Sleep Fragmentation

* Loss of the Brake: Under normal conditions, cortisol binds to GRs to suppress orexin and norepinephrine production, settling the nervous system down.
* Orexin Runaway: With fewer functional GRs, this negative feedback loop fails. Orexin neurons fire continuously without their chemical brake. [2]
* Norepinephrine Flooding: Uninhibited orexin keeps the locus coeruleus in a state of constant excitation. This results in an uncontrolled broadcast of norepinephrine across the brain, producing chronic anxiety, hyper-vigilance, and fragmented sleep. [3, 4]

## 2. HPA Axis Hyperactivity (Systemic Cortisol Rises)

* Feedback Failure: The hypothalamus and pituitary gland rely on GRs to sense circulating cortisol levels.
* Blinded Brain: Because downregulation desensitizes these target cells, the brain mistakenly perceives a cortisol deficiency.
* HPA Runaway: The hypothalamus responds by continually pumping out Corticotropin-Releasing Hormone (CRH). This forces the adrenal cortex to produce abnormally massive quantities of cortisol, which can eventually lead to systemic tissue damage, metabolic issues, and immune suppression. [2, 5, 6, 7, 8, 9]

## 3. Neuroinflammation and Brain Atrophy

* Pro-Inflammatory Shift: At baseline, GR activation keeps microglia (the brain's immune cells) in a calm, anti-inflammatory state.
* Immune Disinhibition: When GRs are sparse or desensitized, microglia shift into an aggressive, pro-inflammatory profile. They release cytokines that damage surrounding neural structures, particularly inside the hippocampus. [10]
* Synaptic Loss: This sustained neuroinflammatory environment halts the production of Brain-Derived Neurotrophic Factor (BDNF), leading to the degradation of dendritic spines and a decreased capacity for learning and memory retention. [11]

## 4. Psychological Vulnerability

* Depression and Trauma: Data published on [PubMed](https://t.co/9J7MClnUhh) and [PMC](https://t.co/Go8F4wRnVD) strongly correlates GR downregulation with major depressive disorder (MDD), burnout syndrome, and PTSD. [12]
* Learned Helplessness: The combination of low neuroplasticity, perpetual biochemical panic (high norepinephrine), and metabolic exhaustion physically traps the brain in a state of learned helplessness.

[1] [https://t.co/2LZTNR6NKG](https://t.co/r5KITx6UVd)
[2] [https://t.co/nR3spk0WgQ](https://t.co/kyksP1vjUw)
[3] [https://t.co/2LZTNR6NKG](https://t.co/vL0FzDcXNw)

[RexesRule ⚓USN ⚓😺 🦝 @CatsRule2023]

The Sound of Silence, audio reel.
June 10, 2026 Rev 1

Credit to Dr. Kevin McCairn @KevinMcCairnPhD for his Substack Report, and to Kenny Carmody @KennyCarmody for his inspiring quote on next to last slide.

[Harry Spoelstra @HarrySpoelstra]

Long-Term Outcomes of Multisystem Inflammatory Syndrome in Children up to 4.5 Years After COVID-19

🚨IMPORTANT new study just dropped: MIS-C in kids is NOT a temporary illness!!

🚨It raises cardiovascular disease risk 14×, hypertension 9×, and gut/lung/brain problems for up to 4.5 years later(=LC)

Earlier “kids recover fine” claims are now officially challenged! Study:👇

➡️ A retrospective cohort study from New York’s Montefiore Health System examined 173 children under 21 with MIS-C versus 346 propensity score-matched controls without MIS-C, all following documented COVID-19 infection.

➡️Follow-up extended up to 4.5 years (March 2020–August 2024) using electronic health records, with MIS-C confirmed by ICD-10 code M35.81 plus CDC/WHO criteria.

➡️Results:
1. MIS-C patients faced markedly elevated risks compared to controls:
- Cardiovascular disorders (aHR 13.88, 95% CI 4.69–41.07),
- Hypertension (aHR 8.86),
- Gastrointestinal disorders (aHR 9.48),
- Respiratory disorders (aHR 3.46), and
- Neurological disorders (aHR 2.02),
- Shock and chronic kidney disease (CKD) occurred almost exclusively in the MIS-C group,

2. Kaplan-Meier analysis showed persistent cumulative incidence in the MIS-C cohort ranging from 6.8% (CKD) to 35.2% (respiratory disorders), with risks diverging and accumulating over years rather than resolving,

3. Preexisting hypertension strongly predicted cardiovascular, neurological, respiratory, and gastrointestinal outcomes,

4. Preexisting diabetes increased CKD risk 49-fold,

5. Older age modestly raised risks of shock and CKD.

6. Sensitivity analyses using stricter MIS-C definitions and alternative respiratory coding confirmed the main results.

7. No mention or data on vaccination and/or reinfection impact.

➡️The study directly challenges earlier reports portraying MIS-C as a transient, self-limited condition with minimal long-term sequelae.

‼️So, MIS-C is not a temporary inflammatory storm that children outgrow. It inflicts severe, lasting multisystem damage that multiplies the lifetime risk of serious cardiovascular disease, hypertension, gastrointestinal, respiratory, and neurological disorders by several-fold to more than ten-fold, while introducing rare but devastating conditions like shock and CKD that almost never occur in peers.
‼️Sadly enough risks continue to accumulate years later.
‼️Earlier short-term “excellent recovery” narratives are contradicted by this longer, rigorous evidence.
‼️Affected children now carry a heavy, potentially permanent burden of chronic illness that will require lifelong medical surveillance and coordinated care or face accelerated morbidity and reduced quality of life!
‼️Of course we need further confirmation, but this does fit the ongoing concerns within the LC science community!
😡So much for paediatric minimalizations!
#AvoidSars2 #AvoidReinfections #ProtectChildren
https://t.co/xXJFs0bFSH

[Mary Talley Bowden MD @MaryBowdenMD]

Update from Japan with Dr. Kevin McCairn and Patient Ken Evans https://t.co/Ls5fs2mmCe

[Charles Rixey, MA MBA (c) @CharlesRixey]

For those wanting to know the latest about our experimental protocol and treatment progress
@MaryBowdenMD interviews @KevinMcCairnPhD and @KenCaptn20114

@HouseLyndseyRN

[PolyBio @polybioRF]

Dr. Tim Henrich presented new findings surrounding long term persistence of SARS-CoV-2 proteins & RNA in Long COVID gut tissue at PolyBio’s recent Spring symposium. “We actually see [gut viral persistence] in both areas, the epithelium—which turns over every several days to week—to the lamina propria where you have long-lived myeloid immune cells… suggesting there may even be replication in some individuals,” said Henrich.

Using a highly sensitive method of detecting viral RNA, “around 20-25% of the time, we see detection… all the way up until 3-4 years after initial infection” in Long COVID patients.

[Harry Spoelstra @HarrySpoelstra]

As I’ve always suspected: Genetic predisposition!

Your genes don’t just raise your risk,

🚨They could turn a past COVID-19 infection into a lifelong sentence of dangerous blood clotting!

➡️“COVID-19 acts as a long-term modifier of inherited thrombophilia phenotypes.”

➡️“Incorporating genetic profiling into post-COVID evaluation may enable precision identification of individuals at risk for persistent hypercoagulability.”

🤔Interesting Russian study!
#AvoidSars2 #AvoidReinfections
https://t.co/peeCLx8WE5

[Concerned Citizen @BGatesIsaPyscho]

🚨💉 “People cleared of Cancer started relapsing - they all had been given Boosters”

“It’s simple - Boosters repress the T-Cell response”

“Cancers went up with each Vaccine”

Wow - The UK’s No.1 News Channel just covered testimony given in US Congress - as to why the Covid Boosters caused Cancer.

Listen to World renowned Oncologist Angus Dalgleish explain.

[P123 🌞 Δψm @P1231032850]

modRNA 💉- Tox - Transfection

[Angloid @angloid0]

Henry Nowak was killed for being White.

Short monologue from recent YouTube video.

Full video - https://t.co/wlahCaHlGE

[Joe Rogan Podcast News @joeroganhq]

Logan Paul on tearing his tricep: "It is depressing, bro. I just don't know how else to say it. I'm not the depression guy. You guys know I'm pretty just gung-ho and happy about life. Every day is a little better, but I'm struggling. I'll be honest."

[Enchanted Heart~ @Wildheart847]

🚨🚫💉 @DrAseemMalhotra TESTIFING
https://t.co/aqXH0s0DXm
@Beardvet @RwPatriot @lsferguson @NoogaJack @Ellmore @Michael1956J @Michael50841844 @HouseLyndseyRN @911Revisionist