Romi Hadary

PhD student @sorekLab @weizmannScience. Studying phage-bacteria arms race 🦠🛡️🧽

[Erez Tzvi Yirmiya @ErezTzvi]

Happy to share our new preprint! We uncovered the full diversity of bacterial TIR-based antiviral immune signaling, massively expanded the known diversity of Thoeris systems, and revealed conservation of TIR-derived immune signals across the tree of life
https://t.co/ZxA5EJd4JH

[Romi Hadary @HadaryRomi]

9/
It was such a fun and inspiring journey 🎉 Huge thanks to @reneechang — it was a pleasure working on this together!
Special thanks to all amazing contributors:
@nath_bechon , @Nitzan_T , @IlyaOsterman , @ErezTzvi , @GarbJeremy , @GilAmitai

[Romi Hadary @HadaryRomi]

📢 Preprint out!
Together with @reneechang and the amazing @SorekLab , we explored viral sponges to map their diversity and function.

Discovered huge diversity, including sponges that inhibit Pycsar & Type IV Thoeris!

https://t.co/ZhHMK7KB6O

[Romi Hadary @HadaryRomi]

8/
Remarkably, 65 sponges inhibit ≥1 immune system, and 25 block multiple. They evolved specificity & diversity, a striking example of the phage–bacteria arms race. Sponges appear key for phages, shaping many bacteria–virus interactions, and new families keep being discovered.

[Romi Hadary @HadaryRomi]

A beautiful and much-needed review on the role of nucleotides in immunity 💫🧬@dinahoch

[Dina Hochhauser @dinahoch]

It’s out! Read my review with @SorekLab on the nucleotide pool as a central playground in antiviral immunity across humans, bacteria and plants! 🧍‍♀️🦠🌿

& the diverse ways in which viruses overcome these nucleotide-based immune mechanisms 🗡️

https://t.co/wipXYcBHRS

[Romi Hadary @HadaryRomi]

Amazing work led by @Nitzan_T – so happy to see it out! 🧬💫

[Nitzan Tal @Nitzan_T]

📢Preprint out!
Excited to share my final work from the @Soreklab!

We mined phage dark matter using structural features shared by anti-defense proteins (viral tools that help phages bypass bacterial immunity) to guide discovery.

Found 3 new families targeting immune signaling!