Dr Robert Ayto

Haematology Education. Portsmouth Hospitals University Trust. Haematology Consultant. Work with fantastic colleagues. Dog lover. Football fan. All views my own.

[Dr Robert Ayto @HaemEdDocRob]

I'm a Haematology Consultant in Portsmouth, UK, passionate about educating the next generation of haematologists and biomedical scientists. This account will keep you up-to-date and support FRCPath exam prep.

Outside of work, it's all about the dogs!

[Dr Robert Ayto @HaemEdDocRob]

@econaturehols Love this shot

[Dr Robert Ayto @HaemEdDocRob]

What would be the best treatment option for this fit female?

[Dr Robert Ayto @HaemEdDocRob]

60-year-old presents with cytopenias.
Please see the linked questions.

#hematology #MedTwitter #hematology

Reference:- https://t.co/mRVqUvGhMl

[Dr Robert Ayto @HaemEdDocRob]

What is the diagnosis and likely genetic abnormality?

[Dr Robert Ayto @HaemEdDocRob]

What is the most likely haematological abnormality?

[Dr Robert Ayto @HaemEdDocRob]

What haematological condition is associated with these X-ray and clinical findings?
#hemepath #hematology #MedEd

See linked question

[Dr Robert Ayto @HaemEdDocRob]

What is the most likely cytogenetic abnormality

[Dr Robert Ayto @HaemEdDocRob]

Which cytogenetic is mostly likely to be found in this condition?

See linked poll

#hematology #hemepath #frcpath

[Dr Robert Ayto @HaemEdDocRob]

Which of these features is not a flow cytometry characteristic of CLL?

MFI - median fluorescent intensity

[European Hematology Association @EHA_Hematology]

Welcome back to the #EHA #ThinkingThursday on diagnostic criteria of #mastocytosis: were your answers correct?

[Dr Robert Ayto @HaemEdDocRob]

Patient presents with pancytopenia - trephine below.

IHC showed cells were CD20 pos, Bcl2 neg, CD10 pos and Bcl6 pos.

What is the diagnosis?

Reference:-
https://t.co/YjLnkrNE8o

#hematology #hemepath #pathology

[Dr Robert Ayto @HaemEdDocRob]

Excellent - active monitoring

[Dr Robert Ayto @HaemEdDocRob]

The patient underwent bi lateral breast implant removal and total en bloc capsulectomy. There was no capsular penetration and tumour cells penetrated the luminal side of the capsule only. CT PET showed no sites of FDG avid disease.

What treatment would you recommend?

[Dr Robert Ayto @HaemEdDocRob]

Correct FLT3-ITD!

[Dr Robert Ayto @HaemEdDocRob]

Which subset of patients would benefit least from Venetoxlax and Azacytidine?

#hematology #hemeonc

[Dr Robert Ayto @HaemEdDocRob]

@nihardesai7 Quite a few in my practice, not sure of the %

[Dr Robert Ayto @HaemEdDocRob]

Patient presents with night sweats, weight loss, itchiness and anaemia?

Abnormal cells stain for CD15, CD30, EBER and MUM1 but CD45-ve.

What is the cell and diagnosis?

#hemepath #MedTwitter #haematology
#hematology

https://t.co/y10ugyATdo

[Dr Robert Ayto @HaemEdDocRob]

Correct answer ALK-be BIA Anaplastic - still time to vote on treatment

[Dr Robert Ayto @HaemEdDocRob]

What is the most likely diagnosis?
AL = anaplastic lymphoma
HD = Hodgkin disease
BIA = Breast Implant Associated

[Dr Robert Ayto @HaemEdDocRob]

Patient presents with splenomegaly, cytopenias and fatigue. A bone marrow was performed. HE below.

What is the likely diagnosis?

#path #oncology #hemepath

https://t.co/abHoKRi0H6

[Dr Robert Ayto @HaemEdDocRob]

The patient underwent bi lateral breast implant removal and total en bloc capsulectomy. There was no capsular penetration and tumour cells penetrated the luminal side of the capsule only. CT PET showed no sites of FDG avid disease.

What treatment would you recommend?

[Dr Robert Ayto @HaemEdDocRob]

A 56 year old female presents with a left breast Seroma - she has previously undergone bi lateral breast implants. Cytology and immunocytochemistry of a suspicious cell infiltrate is seen below. See thread.

#lymphoma #hemepath #hematology

reference:-
https://t.co/ZfBkAQwifJ

[Dr Robert Ayto @HaemEdDocRob]

What is the most likely diagnosis?
AL = anaplastic lymphoma
HD = Hodgkin disease
BIA = Breast Implant Associated