Clonidine in palliative care- A thread 🧵
Clonidine is not a new drug.
Developed in the 1960’s it has been used to manage hypertension, hot flashes, migraine and even ADHD.
Use perioperatively and in ITU for pain relief has been fairly common inc via spinal and epidural route
New therapeutic options don’t come along often in palliative care. When they do there is often understandable hesitancy to introduce these into practice. Clonidine is a good example of this so I wanted to explore more with this thread 🧵 👇
Hot flashes in palliative care ⚡️
A Thread 🧵
Hot flashes with night sweats are common in cancers where treatment leads to a deficiency of oestrogen
Yes lack of oestrogen is the root cause for both men and women
My blog this month on the BMJ Supportive and palliative care forum
Quite a different topic for me but a really important one I believe
“Faecal vomiting- A case of frequently mentioned but rarely seen”
Please have a read and share your thoughts 🙏
https://t.co/CjcxhUyqgm
Opioid switching - A thread 🧵
Not all opioids are the same- that’s where we start this thread.
Morphine is the archetypal opioid and best known but there are a multitude of other options whose use and availability varies across the globe.
Nadhim Zahawi has agreed to pay the £3,000,000 tax bill he lied about and hid from HMRC.
He should be sent to jail for fraud.
RT if you want to see him in jail.
Domperidone, QT interval & prucalopride: a🧵
Prucalopride is now off patent and its price beginning to fall
At the same time, evidence of a gastroprokinetic effect suggests it acts throughout GI tract, not just on the bowel...
https://t.co/vWMG5fFMa9
https://t.co/dCfph84Z8u
@Existential_Doc @revealshadow @griffiths_gill The old Grasebys were drivers due to their mechanism. Medical physics colleagues corrected me when the T34s came along (& now the Bodyguard T) that these are syringe pumps.
🔉BRAND NEW SCOTTISH PALLIATIVE CARE GUIDELINES WEBSITE AND APP LAUNCHES TODAY 🔉 accessed from the original website which redirects you or by downloading the app and searching for them @APM_Hub@APMPostTweets@APMPostTweets@APCAssociation @PalliativeWork @DonnaWakefield_ @
Rishi Sunak has decided that the £14.9bn of PPE fraud cannot be investigated & has written it all off
This is the same amount of money as the entire budget for General Practice & Primary care for a year
Imagine writing off 330million consultations, GPs, Nurses etc for a year
There is a reason why the German Shepherd has been the go to dog for the last 70 years. But I believe Giant Schnauzers like PD Albert & TPD Bert have the qualities to supplement our current breeds the GSD, Malinois and Dutch herder. Great day with the boys and ITV yesterday