🚨Neuroendocrine marker expression in mucosal melanomas of the H&N might represent an important diagnostic pitfall!
Shah et al. in IJSP (link: https://t.co/jEOcoWxX5u) show how synaptophysin alone might not be the best screening marker in the dx work-up.
#PathTwitter#ENTPath
اتق الله، مستعد انه يكون هو اهله خصمائك يوم القيامه؟
قال النبي صلى الله عليه وسلم قال: ليس المؤمن بالطعان ولا اللعان ولا الفاحش ولا البذيء. رواه الترمذي والحاكم وصححه الألباني.
وقال لمعاذ: كف عليك هذا يعني لسانه. قال وإنا لمؤاخذون بما نتكلم به قال: ثكلتك أمك وهل يكب الناس في النار على وجوههم أو على مناخرهم إلا حصائد ألسنتهم. رواه الترمذي.
A nice case of Ochronosis. Banana-shaped, ochre-yellow (golden-brown) pigment in thickened dermal collagen bundles. Can be endogenous from alkaptonuria but more frequently exogenous origin secondary to hydroquinone treatment. #DermX#Dermpath#Dermtwitter#pathology#MedEd
Histology 📷: me
Clinical📷: Dermnet NZ. Waikato District Health Board.
Proud to complete my Certificate in Oral & Maxillofacial Pathology at the University of Florida🐊.
Grateful for the journey, the people, the lessons & the memories💜
Pagetoid Spread of DCIS ⛏️👷♂️🔬
Atypical ductal epithelial cells undermining the ductal epithelium of large ducts in a pagetoid distribution.
#PathX#PathTwitter#breastpath
@Harth_almleihat @AFC_Capital@thearsfamily97 يقول الله تعالى: يؤذيني ابن آدم يسب الدهر وأنا الدهر بيدي الأمر أقلب الليل والنهار. رواه البخاري ومسلم واللفظ للبخاري.
Interesting variants of mucoepidermoid carcinoma. Part 1
- They can be ciliated
- They can have acinar differentiation (it is not acinar cell carcinoma)
- They can be spindled (usually keratin positive)
- They can be oncocytic (these were the old oncocytic carcinomas described in salivary glands which no longer exist)
Dr. Bishop #USCAP2026 #pathology #PathX #PathTwitter