Happy to publish our work on the subtype-specific noncompetitive inhibition mechanism of the human P2X3 receptor by sivopixant, an investigational drug for chronic cough in @PLOSBiology. Great collaboration with CPU. Congrats to Zhao and all involved! https://t.co/BC05YcdxSI
Happy to share our preprint on the structural and functional analysis of the plant MRS2 Mg2+ channel, revealing plant-specific cytoplasmic Mg2+ sensing and stepwise gating. Great collaboration with Profs. Yu at CPU, Wang at Fudan, and Tanoi at UT!
https://t.co/0cWiHIny2e
https://t.co/mUuSd92TLe
New preprint from our lab!
Solving antagonist-bound GPCR structures is becoming easier with fusion markers, but linker optimization between GPCR and marker is still a bottleneck. (1/2)
3月23日のCBI研究機構 ・中性子産業利用推進協議会の合同シンポ「New Structure Based Drug Discovery」にてお話させていただきます。他の演者は東大の濡木先生、理研の山本先生、上智大の近藤先生です。オンライン開催で、参加申し込みは3月16日まで。ご興味のある方は是非。https://t.co/RpERBMFfRP
Happy to share our work on the subtype-specific, noncompetitive inhibition mechanism of the human P2X3 receptor by sivopixant, an investigational drug for chronic cough. Great collaboration with Profs. Guo and Yu at CPU. Congrats to Zhao and all involved.
https://t.co/e8XunFc8Xi
Happy to publish our collaborative paper on the interspecies drug response variations between human and rodent P2X7 receptors. Great collaboration with Prof. Yu at China Pharmaceutical Univ and Prof. Liu at SIMM, CAS. Congrats to all involved! @NatureComms https://t.co/UCUoxy9ORQ
Happy to publish our collaborative paper on the interspecies drug response variations between human and rodent P2X7 receptors. Great collaboration with Prof. Yu at China Pharmaceutical Univ and Prof. Liu at SIMM, CAS. Congrats to all involved! @NatureComms https://t.co/UCUoxy9ORQ