Luke Hoeppner

Molecular biologist @UMNews, Hormel Institute studying #lungcancer & vascular biology. Associate Professor, Husband, Father of 4, Runner, @MLB fan.

[Luke Hoeppner @HoeppnerLab]

Excited to share our new work revealing the role of IKKα in lung cancer progression in @Nature_NPJ Precision Oncology! Outstanding teamwork by our group! @UMNResearch @UMNCancer #OpenAccess https://t.co/M5KBr3ZaG9

[Luke Hoeppner @HoeppnerLab]

@mike_feigin Love the Brewers hat! I’m a huge MIL fan!

[Luke Hoeppner @HoeppnerLab]

@ZebrafishRock Sorry, we don’t have them. Thanks for checking and best wishes.

[Leading Report @LeadingReport]

BREAKING: Rep. Thomas Massie has joined 26 other elected officials and 45 candidates in publicly stating the COVID shots must be pulled off the market.

[Luke Hoeppner @HoeppnerLab]

@JeffFletcherOCR @JeffFletcherOCR Is Barria starting tomorrow (Sun, 9/24)?

[Luke Hoeppner @HoeppnerLab]

@mike_feigin Just tell your son, "All Apologies", and things should be cool...

[Luke Hoeppner @HoeppnerLab]

Spot on…

[Dr. Glaucomflecken @DGlaucomflecken]

Elsevier is losing editors

[Luke Hoeppner @HoeppnerLab]

Flow cytometry...

[Morissa Schwartz 📚 (Dr. Rissy) @MorissaSchwartz]

How!?

[Luke Hoeppner @HoeppnerLab]

With the exception of the 2023 Oakland A’s…

[Wayne @Toaster_Pastry]

I’m convinced any modern MLB team could beat the 1927 NY Yankees.

[Luke Hoeppner @HoeppnerLab]

@mike_feigin Not here! We woke up to snow in Minnesota this morning and I had to shovel our driveway.

[Luke Hoeppner @HoeppnerLab]

Our findings suggest that IKKα drives NSCLC growth through the activation of ERK signaling via DARPP-32-mediated inhibition of PP1 activity.

[Luke Hoeppner @HoeppnerLab]

Excited to share our new work revealing the role of IKKα in lung cancer progression in @Nature_NPJ Precision Oncology! Outstanding teamwork by our group! @UMNResearch @UMNCancer #OpenAccess https://t.co/M5KBr3ZaG9

[Luke Hoeppner @HoeppnerLab]

IKKα ablation in human lung adenocarcinoma cells reduced their anchorage-independent growth in soft agar. Mice challenged with IKKα-ablated HCC827 cells exhibited less lung tumor growth than mice orthotopically administered control HCC827 cells.

[Luke Hoeppner @HoeppnerLab]

Inexpensive fluorescence imaging of #zebrafish for classroom and science outreach settings.

[Jake Hines @jhhines2]

Final version of our glowscope project is now out at https://t.co/oWxCk8aUkU
The paper adds inexpensive fluorescence capability to the wonderful smartphone scopes that @ScopesWorkshop developed and tirelessly brings into classrooms and science outreach settings.

[Luke Hoeppner @HoeppnerLab]

@hartonomdphd Love the creativity and "science humor"!

[Luke Hoeppner @HoeppnerLab]

Accepted for publication today! More soon! Excellent work, team!

[Luke Hoeppner @HoeppnerLab]

Our newest preprint is out! We found that IKKalpha directly phosphorylates DARPP-32 to inhibit protein phosphatase 1 (PP1) leading to activation of ERK signaling in #lungcancer.

[Neal Augenstein @AugensteinWTOP]

Things I didn’t know before I was diagnosed w Stage IV #lungcancer in Nov 2022
1. For many (like me) 1st symptom was persistent cough. When that’s case, initial tumor has likely spread.
2. To qualify for CT lung cancer screening, you had to smoke a pack a day for 20 yrs.

[Luke Hoeppner @HoeppnerLab]

Currently looking to hire a postdoc. Please reach out &/or apply.

We use cellular function studies, biochemistry, molecular assays, mouse & zebrafish models, & human specimens to study the molecular basis of human disease including cancer, cardiovascular disease, & lung injury.

[Joan D. Beckman @jd_beckman]

Excited to have this work published! @JTHjournal @UMNBME @UMNHOT