Claude Fable 5.2 - Flute Sonata in A minor. The opening 8 bars use a figured bass by Corelli. After that, it’s all Fable. This is the first time I remember seeing a 9-8 suspension in the basso continuo (third movement, measures 1 and 11, for example). Opus wrote ninths into the solo part, but not into the figured bass. I think this shows a greater confidence in employing dissonance.
Prompt 1: “Use this figured bass as the starting point for a flute sonata movement in the Baroque style. Use two staves for the basso continuo and one for the flute. Respond with only the code block. [LilyPond code]”
Prompt 2: “Compose an allegro to follow this movement.”
Prompt 3: “Compose a largo, the sonata's third movement. The movement after this, the fourth, will be the last.”
Unfortunately, Fable ran out of usage before it could finish the fourth movement.
(Extra High effort)
From punching holes in paper in 1881 to storing everything in an invisible cloud by 2013, data storage evolved from physical objects you could hold to infrastructure you’ll never see. Each format packed more into less, and the trend shows no signs of stopping.
A 30 percent vitamin C solution dissolved in DMSO cleared 86 percent of basal cell skin cancer lesions within eight weeks in a clinical trial. In a randomized study published in Biomedicine & Pharmacotherapy, researchers tested a topical mix of high-concentration ascorbic acid and dimethyl sulfoxide, a solvent that helps substances penetrate deeply into the skin.
Applied twice daily for eight weeks, the combination produced complete clearance in 13 of 15 lesions (86.7 percent) among patients with low-risk basal cell carcinoma. This rate exceeded that of the standard topical treatment imiquimod, which cleared 8 of 14 lesions (57.1 percent). The vitamin C–DMSO formulation also caused fewer side effects and avoided the lasting skin hypopigmentation sometimes seen with conventional topical therapies.
Because basal cell carcinoma is the most common form of skin cancer worldwide, these early results suggest a possible low-cost, non-invasive option. Larger trials are still required before the approach can be adopted as standard care.
[Burke, B., & Bailie, J.-E. (2022). Randomized trial of topical ascorbic acid in DMSO versus imiquimod for the treatment of basal cell carcinoma. Biomedicine & Pharmacotherapy, 148, 112710. DOI: 10.1016/j.biopha.2022.112710]
A year ago today we published The Last Economy by @EMostaque.
Since then, scores on the hardest AI benchmarks have risen sharply, while the cost of useful intelligence has kept falling.
The book asks what an economy does when intelligence is no longer scarce.
https://t.co/LvxqDtnCzz