IC research Radboudumc

New publications and research activities from the Radboudumc Intensive Care Research Department

[IC research Radboudumc @ICresearch_Rumc]

Please follow us on LinkedIn (https://t.co/hljptAR0T4) to stay up to date on our most recent research & publications!

[IC research Radboudumc @ICresearch_Rumc]

Former ICU patients encounter more new disease-episodes and contacts with their general practitioner than the comparison group before and 5 years after ICU admission. Read the full article here:

https://t.co/csHPsvkhxs

[IC research Radboudumc @ICresearch_Rumc]

Dries van Sleeuwen et al. performed a prospective cohort study to investigate the impact of Intensive Care Unit (ICU) admission on primary care.

[IC research Radboudumc @ICresearch_Rumc]

Job satisfaction is largely determined by the degree of perceived autonomy, connectedness, competence, and recognition. They also included recommendations to increase job satisfaction in order to retain nurses in the ICU profession.

https://t.co/GOKsRfkOAq

[IC research Radboudumc @ICresearch_Rumc]

In their publication, Gijs Hesselink and Marieke Zegers describe a multicenter qualitative study into the factors that influence the job satisfaction of ICU nurses.

[IC research Radboudumc @ICresearch_Rumc]

Researchers Aron Jansen, @matthijskox82 and Peter Pickkers from @radboudumc demonstrate that Cytosorb therapy effectively attenuates circulating cytokine concentrations during systemic inflammation.

Read the full article: https://t.co/PDYkmoo6qU

@radboudumc_weet @CytoSorbents

[IC research Radboudumc @ICresearch_Rumc]

Lucy Porter, Marieke Zegers et al. developed and externally validated a prediction model for quality of life after ICU.

Read the full article here:
https://t.co/lizTywYkSs

[IC research Radboudumc @ICresearch_Rumc]

Read their full article on #CritCareMed:

Development of Moral Injury in ICU Professionals During the... : Critical Care Medicine (https://t.co/qZbwdIK9yO)

[IC research Radboudumc @ICresearch_Rumc]

Niek Kok, Marieke Zegers et al. conducted 62 serial interviews with 26 ICU professionals over the course of the #COVID19 pandemic and concluded that awareness about #moralinjury is needed. Moral injury differs from #burnout.

[IC research Radboudumc @ICresearch_Rumc]

Read the article here:

https://t.co/BoGksKTbDi

[IC research Radboudumc @ICresearch_Rumc]

Disease heterogeneity in #COVID19 warrants deeper understanding. Niklas Bruse, Peter Pickkers, and @matthijskox82 applied clinical phenotypes previously identified in non-COVID-19 sepsis patients to a large population of critically ill COVID-19 patients.

[IC research Radboudumc @ICresearch_Rumc]

They found that patients with one phenotype particularly benefited from dexamethasone treatment, reflected by improved survival. This shows that phenotyping COVID19 patients may aid prognostication, prediction of treatment efficacy, and facilitation of personalized medicine.

[IC research Radboudumc @ICresearch_Rumc]

Read the full article here: https://t.co/8Wr1ekjtho

[IC research Radboudumc @ICresearch_Rumc]

A common method to assess immune function in critically ill patients is to determine the cytokine production capacity of isolated leukocytes.

[IC research Radboudumc @ICresearch_Rumc]

In their latest publication, ICU researchers Aron Jansen, prof. Peter Pickkers and dr. @matthijskox82 demonstrate that results of these ex vivo or in vitro assays should be interpreted with caution, as they do not adequately reflect the in vivo immune response.

[IC research Radboudumc @ICresearch_Rumc]

A stepped wedge cluster RCT in 6 ICUs to improve ICU care @Bramtilburgs @markvdboogaard

[IC research Radboudumc @ICresearch_Rumc]

Our research proposal: PRevention of pAtient’s agItation and enhancement of their SafEty (PRAISE), using a multicomponent pharmacological intervention to reduce physical restraints use in the ICU, is granted @ZonMw (program GGG).

[J. of Medical Ethics @JME_BMJ]

"Morisprudence: A theoretical framework for studying the relationship linking moral case deliberation, organisational learning and quality improvement" by Niek Kok, Marieke Zegers, Hans van der Hoeven, Cornelia Hoedemaekers and Jelle van Gurp

#bioethics

https://t.co/ewAbuFqNVv

[IC research Radboudumc @ICresearch_Rumc]

Our department is not only conducting research in adults! Colleagues Nori Smeets & @saskiaNW examined kidney function in newborns and showed how it develops.

Read the article here:
https://t.co/slIZkASjCz

[IC research Radboudumc @ICresearch_Rumc]

They propose less registration burden by introducing a core set of indicators and more focus on a learning- instead of a "ticking-off" culture.

Read the article here:

https://t.co/G96osNf0a9

[IC research Radboudumc @ICresearch_Rumc]

Learning and improvement should be more central to quality measurements. Researchers Marieke Zegers, @gijs_hesselink and Hans van der Hoeven advocate for this in their article 'Time to see quality measurement differently: focus on reflection, learning and improvement'.