Our assay uses upcyte® hepatocytes, which retain liver-specific functions such as:
CYP450 enzyme activity
Drug transporter expression
Albumin production
A recent publication titled "Assessment of chemical extracts of urban air for endocrine disruption using a serie of in vitro bioassays: a case study in Montreal, Canada" utilized INDIGO's AR and ERα assay kit!
In observance of Memorial Day, INDIGO Biosciences is closed. Today, we honor and remember the brave men and women who gave their lives in service to our country.
We will be back in the office on Tuesday, May 26th.
INDIGO’s GR/NF-κB Transrepression Assay can help researchers assess whether a compound influences GR-mediated repression of inflammatory signaling, generating functional data that may support ranking, differentiation, and follow-up study design.
We recently added GPR39 to our assay portfolio, giving researchers a precise and reliable way to characterize GPR39 activators and inhibitors with high reproducibility and minimal lot-to-lot variability.
Find this reporter assay and more on our website! https://t.co/YK8KJUnOJ1
Evaluating a compound across the entire nuclear receptor family provides insights into potential off-target interactions and ensures a comprehensive safety and efficacy profile.
For teams considering how transrepression data might fit into a broader screening strategy, this blog provides a useful overview of the biology and the assay application.
Read now: https://t.co/0pbTnrldxU
This recent publication titled "Metabolomic profiling and biological evaluation demonstrate the antioxidant, PPAR-γ, TAAR1, and FABP4 modulatory potential of Strelitzia species" utilized INDIGO's PPARγ assay kit!
Read now by clicking on the link below 🎉
https://t.co/Udv09woFMJ