Isidore Rigoutsos

Director, Computational Medicine Center (@CompMedicineTJU), Sidney Kimmel Medical College, Thomas Jefferson University (Any opinions expressed here are my own)

[Isidore Rigoutsos @IRigoutsos]

Do you know where in the cell your favorite microRNA/isomiR, tRNA-derived fragment (tRF) or rRNA-derived fragment (rRF) hangs out?

The answer may surprise you.

We discuss all of this in our latest preprint: https://t.co/G8z3ctyqEL

#isomiRs #tRFs #rRFs #miRNA #tRNA #rRNA

[Isidore Rigoutsos @IRigoutsos]

We are hiring! Apply using the link below. I look forward to speaking with you.

[CompMedicineTJU @CompMedicineTJU]

Do you want to build tools that help scientists make sense of biomedical #data and are used daily by people worldwide? If this appeals to you and you are a #SoftwareDeveloper, join our team at @JeffersonUniv!
https://t.co/NWF5xlEbS4

#recruiting #hiring #computationalmedicine

[CompMedicineTJU @CompMedicineTJU]

Did you know that tRNA fragments contribute to the immune response pathway? Read all about our new findings
on how 5'-tRNA HisGUG halves activate Toll-Like receptor 7 (TLR7)
at https://t.co/297wNdCwnr

@KamleshGaneshP1, @yohei_kirino
#tRF #computationalmedicine

[Isidore Rigoutsos @IRigoutsos]

We just released #isoMiRmap profiles of all isomiRs in the @1000genomes project and the 33 cancers of @theNCI 's Cancer Genome Atlas project.

Get the profiles at: https://t.co/w4FZ6n3GTk

#TCGA #1000Genomes #NCI #NIH #Jefferson #PrecisionMedicine #Computational Medicine Center

[Isidore Rigoutsos @IRigoutsos]

Want to look for #miRNA isoforms (#isomiRs) in your RNA data? Check out our #isoMiRmap tool: https://t.co/lVxhFrtHqv
Detects #SNP, flags ambiguous sequences, and is really fast. Codes at: https://t.co/w4FZ6n3GTk

#Jefferson #PrecisionMedicine #ComputationalMedicineCenter

[Isidore Rigoutsos @IRigoutsos]

#tRNA fragments rule!
I hope you enjoy our latest review on #tRFs as much as we did putting it together: https://t.co/wWtsPCU7kj

#tRFs #tRNA #Jefferson #PrecisionMedicine #HealthDisparities

[Isidore Rigoutsos @IRigoutsos]

In our latest paper, we linked #tRNAfragments to the #mitochondria to multiple #cancer types, to #introns, to specific gene #pathways and to several categories of #junkDNA...

[CompMedicineTJU @CompMedicineTJU]

#tRNAfragments, the #mitochondrion, #cancer, #repeatelements (#junkDNA), and #disparities -- seemingly unrelated yet deeply connected as we show in our latest work: https://t.co/c7kJPlzwoY

Congratulations to the #computationalmedicine team at #Jefferson. Go #PrecisionMedicine!

[Isidore Rigoutsos @IRigoutsos]

ICYMI -- #BigData in #cancerresearch https://t.co/OpObfOJsqZ

[Jefferson Health @TJUHospital]

On the blog - Jefferson Harnessing "Big Data" to Broaden Cancer Research: https://t.co/5SGtIG2SFg.

[Isidore Rigoutsos @IRigoutsos]

ICYMI:
Why We Merged: Jefferson, Philly U. Presidents Explain https://t.co/4NbX0p6nTV via @phillymag

[CompMedicineTJU @CompMedicineTJU]

Join us again on November 07 for this year's PurpleStride Philadelphia 2015 to benefit pancreatic cancer research http://t.co/3vwt5gVIWB

[Isidore Rigoutsos @IRigoutsos]

Merci bien @YannisDelmas. Mieux vaut tard que jamais 😉

[Isidore Rigoutsos @IRigoutsos]

#PrecisionMedicine questions that we will need to address before long: http://t.co/aEao2zS4b3

[Isidore Rigoutsos @IRigoutsos]

Behold the power of the isomiRs... https://t.co/E76uAZ1DUM

[CompMedicineTJU @CompMedicineTJU]

New CMC article: #isomiRs (which we showed before depend on #Population, #Race, #Gender) matter in #BreastCancer - http://t.co/2Hscimu64K