Thanks Marie Scully for highlighting our paper on #ADAMTS13#TTP @ITNProfile @KULeuvenKulak@icosagen Transforming the major autoantibody site on ADAMTS13: spacer domain variants retaining von Willebrand factor cleavage activity | Haematologica https://t.co/4KJ0tslhoS
6 non-overlapping fragments of ADAMTS13 were used to develop and validate a fine epitope mapping ELISA of autoantbodies in iTTP. This high-throughput assay may be used in future clinical studies. Read more at #RPTH: https://t.co/qgFr941coY @kvhoorel@KU_Leuven@VoorbergJ
Currently-published epitope mapping data of anti-ADAMTS13 autoantibodies in iTTP is broad due to the use of large protein fragments. Learn how @kvhoorel and colleagues fine-mapped these epitopes in 18 patients with iTTP. Results ➡️ https://t.co/qgFr94iNgw @KU_Leuven@VoorbergJ
Great collaborative work by the Vanhoorelbeke-team @KULeuvenKulak and Andres Mannik's cloning factory @icosagen. Nicely executed by star PhD student Kadri Kangro of @ITN_PROFILE https://t.co/XZLLpvrs6V
In vitro #diagnostics very slow in entering the market. WHY? Delays go about upscaling difficulties, risk & profit, complexity of biology. ‘And probably we need more #women in the field too!’, says professor Joanne Macdonald, the only female at the panel discussion @DIATECH2020