@Gastronaut___@nehapadhi @DrAkhilX @BadalGondane @DrShivu_tweets From https://t.co/S53GdkW3ai
Have not run in to this problem frequently but it is what I was referring to.
@Gastronaut___@nehapadhi @DrAkhilX @BadalGondane @DrShivu_tweets I agree, the only time I am referring to is when (toward the terminal end of resolving a DKA) the patient appears to have a persistent NAGMA with high chloride (due to large amounts of saline). At that stage a small dose of bicarb usually is sufficient to correct it.
@Gastronaut___@nehapadhi @DrAkhilX @BadalGondane @DrShivu_tweets Anecdotally (although over probably 100 DKA patients), other than *rarely* having to give a little bit of bicarb at the end of a DKA due to iatrogenic hyperchloraemia I haven't seen any issue with saline.
@Gastronaut___@nehapadhi @DrAkhilX @BadalGondane @DrShivu_tweets There's quite a lot written on theoretical benefits and trends towards biochemical surrogates but is there any new evidence demonstrating an actual difference in clinical outcomes? It's been a while since I looked at it. Regarding DKA crystalloid choice specifically.
Getting ready for #StarTrekDay with some iconic Trek speechifying from 50 years ago. "To James T. Kirk, captain of the Enterprise." (When that music subtly chimes in halfway through? Goosebumps every time.) #TheUltimateComputer
🦠NEW VARIANT—a new #SARSCoV2 variant C.1.2 just identified in South Africa & several countries, with concerns it could be more infectious and evade vaccines. #C12 also has mutation rate that is nearly **twice as fast** as the rate of the other variants.🧵
https://t.co/r4RReDcAIe
One of my favorite scientific figures is this one of the entropy levels of 100 world cities by the orientation of streets. The cities with most ordered streets: Chicago, Miami, & Minneapolis. Most disordered: Charlotte, Sao Paulo, Rome & Singapore. Paper: https://t.co/DTd5JiahmF