A man with diabetes is making his own insulin after cell transplant.
A 42-year-old man with type 1 diabetes has become the first patient in the world to naturally produce insulin again after receiving gene-edited pancreatic cells.
Using CRISPR-Cas12b technology, scientists reprogrammed donor islet cells to evade immune system attacks that normally destroy transplanted tissue in diabetics. This breakthrough eliminates the need for lifelong immunosuppressive drugs, which often carry severe side effects.
The patient received nearly 80 million of these “hypoimmune” cells, which survived and thrived in his body. Four months later, doctors confirmed the cells were producing insulin by detecting C-peptide spikes after meals.
While still in early trials, this marks a potential revolution in diabetes care, showing that the disease could one day be managed without daily insulin injections. If scaled, it could transform the lives of millions living with type 1 diabetes worldwide.
[Carlsson, Per-Ola, et al. “Survival of Transplanted Allogeneic Beta Cells with No Immunosuppression.” The New England Journal of Medicine, Aug. 4, 2025.]
@PugPrincess1983 My daughter has it too, it was scary at first but she has found meds that work for her. I hope your son had the same result soon. And honestly she was so relieved to know what was wrong that some of her stress was relieved by that. Hoping your son is released soon!
This is how @NianticHelp is responding to my friend who got his account hacked and de-linked within seconds.
Dean, whoever are you, this is no way to respond to a player who has been playing your game from 5 years. Extreme tone deaf response.
@michaelsteranka@pokemongo
@ItsFleeceKing And I did wonder why we were not making the game uneven when we (cough, cough-me) did remotes for hours at a time. Or was just an excuse before?
Some reasonable ideas for remote raids every day 💡
A daily remote raid limit of 20 instead of 5, and reduced back to the old prices. A far more reasonable limit in my opinion, helps for hosting raid hours, and offers more flexibility to do other random raids other than tier 5s.
The prices being doubled from what they used to be means a lot of people simply don’t even do their 5 remote raids every day. The daily limit is one thing, but the doubled prices are another. Both are problematic, but I would argue the price increase is more problematic for most people. Older prices were far more reasonable, and I’m a firm believer in trying to make things more accessible, cheaper and easier for people.
A free daily remote raid pass. Getting a free in person raid pass everyday is nice, but the reality is a lot of people don’t any raids in person for a variety of reasons. Having one free, daily remote raid pass would give every single player an opportunity to do a legendary raid each day, which is so helpful for rural communities in particular.
Lastly, when inviting people to a raid, blank out people who have hit their daily raid limit. It makes no sense why we’re still able to invite people to our raids who can’t join and see the invite because they’ve hit their limit. It’s a waste of time.
Feel free to retweet this if you like the ideas, and leave any suggestions below on what you think would improve remote raids moving forward on a daily basis. Hope this was constructive and reasonable.
#PokemonGO