Invivyd

Invivyd is improving lives with medicines for serious infectious diseases. Pro-human. Anti-virus. Opposed to COVID and spike protein "garbage" in all forms

[Invivyd @Invivyd]

@bhanlon15 @JudyandHuahua Ziyad is a *very* smart guy and always brings data

[Jerome Adams @JeromeAdamsMD]

Just a ($8 billion) cold…
🦠

[Jon Douglas @atranscendedman]

Researchers estimate long COVID could cost the US more than $8 billion by 2027.

At least 44 million Americans have reported symptoms, with lost work productivity driving over 90% of the economic burden.

https://t.co/ttnp6kwqGn

[Invivyd @Invivyd]

@DonEford @cfs_research @AnciraBecky Thanks for thinking of us :). There are extraordinary technical challenges in that short sentence you wrote - but someone oughta try. We’ll put it on the list!!

[Invivyd @Invivyd]

A pervasive CV risk factor. Every infection is a potential problem.

[Harry Spoelstra @HarrySpoelstra]

L0NG C0VID IS QUIETLY WRECKING HEARTS.

Maybe time for a recap based on 2026 science.

Here’s the comparison for MACE, Stroke, Deadly Clots & overall CV risks:

➡️MACE (heart attack, stroke, heart failure)
• Non-COVID: HR 1.0
• COVID-19: 1.8–3.9x
• Long COVID: ~4.5x

➡️Stroke (ischemic):
• Non-COVID: HR 1.0
• COVID-19: ~2–3x
• Long COVID: ~3.5x

➡️Deadly clots (PE / VTE):
• Non-COVID: HR 1.0
• COVID-19: ~2–4x
• Long COVID: 3.2–4.4x

➡️Overall CV risks:
• Non-COVID: baseline
• COVID-19: ↑1.5–2.5x (arrhythmias, CAD, HF)
• Long COVID: 2–4.5x higher

Long COVID adds extra danger beyond regular post-COVID.

Risks hit even non-hospitalized patients and last for years.

Vax may reduce risks but certainly doesn’t erase it.

Absolute risks lower in young/healthy, but serious if older/comorbid.

‼️Today’s evidence shows that while any COVID-19 infection elevates cardiovascular risks, long COVID dramatically amplifies them, making proactive heart monitoring essential for affected patients.

Bottom line: Get your heart checked post-Covid19/ LongC0vid and #AvoidSars2 #AvoidReinfections!

🚨C0VID-19/L0NG C0VID are serious CV RISK FACTORS!

[CIDRAP @CIDRAP]

CDC confirms 59 new measles cases, 1,952 total

The US is inching closer to surpassing last year’s total in just the first half of 2026.

Read more: https://t.co/nX5pEEW43u

📷: CDC

[Invivyd @Invivyd]

We’re excited to be attending this year’s @ASCO annual meeting, where we will be presenting a de novo poster of a subset analysis from the CANOPY trial. 

If you’re planning to attend, visit us at booth #10047. 

Learn more:
https://t.co/PPCEYgPHkY  

#ASCO2026 #ASCO #AntibodyInnovation

[CIDRAP @CIDRAP]

A retrospective cohort study suggests that myocarditis rates surged during COVID and stayed high.

Rates rose roughly 80% above baseline during the pandemic and disproportionately affected Black patients.

Read more: https://t.co/PVc13O9Vp2

[Invivyd @Invivyd]

Whether you’re a world-class athlete like @lindseyvonn or a busy parent juggling it all, supporting your immune system and antibodies can start with a few simple, everyday steps.

Take our wellness assessment to learn more about your immune readiness and antibody protection: https://t.co/ZwRJB3gPBr

#AntibodiesforAnyBody

[Ruth Ann Crystal, MD @CatchTheBaby]

MIT found Alzheimer's-like amyloid plaques in the brains of people who died of COVID. https://t.co/QbSJWJQhGW

Spike proteins were clustering with amyloid.

This was not in older adults with pre-existing disease.

It was caused by COVID.

[Invivyd @Invivyd]

“If you want to find the limitation of any vaccine, you have a really simple job: look in the mirror."

At @POLITICOLive’s Health Care Summit, our Chairman of the Board, Marc Elia, reframed how we should think about immune protection.

Vaccines are powerful, but they rely on your immune system to respond. Monoclonal antibodies offer a different approach.

#POLITICOHealth #Antibodies #Innovation

[Invivyd @Invivyd]

As a general matter, introducing dysfunctional perfusion, inflammation, and a viral protein into the brain would seem bad. And perhaps we are learning it is a specific matter, about which we may have reasonable concern.

[Vipin M. Vashishtha @vipintukur]

SARS-CoV-2 spike protein may directly amplify brain inflammation.

➡️ Researchers found that spike proteins can colocalize with amyloid-β (Aβ) and trigger distinct inflammatory responses in microglia — the brain’s immune cells.

➡️ This raises important questions about potential long-term neurodegenerative consequences of COVID-19. 1/

[Invivyd @Invivyd]

These processes are critical to understand

[Harry Spoelstra @HarrySpoelstra]

Endothelial dysfunction and metabolic biomarkers in post-COVID-19 syndrome

🚨A nightmare study for many!

FOR EVERYBODY: 9 months after your COVID-19, your blood vessels are STILL damaged, with probably biomarkers to prove it!

1. Study design:
German prospective cohort (n=262 adults) compared blood biomarkers ~37 weeks post-SARS-CoV-2 infection (PCS patients + recovered) versus uninfected controls.

2. Endothelial dysfunction:
- Soluble thrombomodulin (sTM) and lactate dehydrogenase (LDH), two established markers of endothelial (blood-vessel) damage, were significantly elevated in the combined infected group (UOC PCS + LIFE Cov+) versus never-infected controls.

- So, previously infected individuals had significantly higher soluble thrombomodulin (TM) and lactate dehydrogenase (LDH), independent of PCS diagnosis or fatigue severity.

- Critically, there were no significant differences between the PCS group and the LIFE Cov+ group for these markers.

3. Metabolic disruption:
- Clear alterations in arginine biosynthesis and taurine/hypotaurine pathways, indicating impaired nitric-oxide (NO) metabolism with reduced L-arginine and taurine levels.

→In plain terms: the vascular damage signal was just as strong in the symptom-free recovered people as in those still suffering from fatigue and other PCS complaints. The same held for the metabolic disruptions (impaired arginine biosynthesis and taurine/hypotaurine pathways linked to nitric-oxide production).

4. Fatigue-specific signal:
- High-fatigue PCS patients (top MFI-20 quartile) showed elevated linoleic acid (LA) plus monounsaturated fatty acids oleic (OA) and palmitoleic (PA).

→The fatty-acid signature specific to high-fatigue PCS adds a potential severity marker.

5. Notes:
- Changes persisted already up to 9 months after infection.
- PCS remains symptom-based, but these markers offer objective, measurable signals of underlying vascular and metabolic damage!
-The discussion and results treat the observed endothelial and metabolic changes as consequences of a single infection and do not speculate on additive damage from subsequent exposures.
- Limitations well noted.

‼️So, COVID-19 leaves detectable, objective blood-vessel and metabolic damage in the bloodstream nearly a year later, even if you feel completely fine and never had Long COVID symptoms.
Specific fatty-acid spikes flag severe post-COVID fatigue. The “it’s all in your head” narrative for many post-covid people is directly contradicted by these biomarkers!
These findings, solidly backed by prior 2021–2025 evidence, prove that COVID-19 inflicts measurable, persistent endothelial and nitric-oxide metabolic damage up to nearly a year later, even in fully symptom-free survivors, thereby supporting the implementation of routine biomarker screening, but even more importantly: #AvoidSars2 #AvoidReinfections. YOU ARE NOW A CV RISK PATIENT!
https://t.co/dkyr9HXTyO

[Invivyd @Invivyd]

@ChristosArgyrop Could this be the first time anyone has written “crixivan” on X?!

[Invivyd @Invivyd]

We will host a conference call on Thursday, 5/14/26 at 8:30 a.m. ET to discuss our Q1 financial results and provide a corporate update. Visit link for details: https://t.co/3sVTIK3Jpe

[Invivyd @Invivyd]

Understanding your health and how the body works shouldn’t be confusing or intimidating – it should be empowering.

This movement is about helping everyone understand the potential that any body has to enhance their immune system, including antibody protection.

Learn more about antibodies at https://t.co/ZwRJB3gPBr.

#antibodiesforanybody

[Invivyd @Invivyd]

@TakeWeightOffMD Yes

[Invivyd @Invivyd]

An awe-inspiring place just a few blocks from Invivyd HQ. Visit it and the rest of Yale for inspiration!

[Rare Biblio @RareBiblio]

The Beinecke Rare Book & Manuscript Library at Yale looks like a giant glowing cube from the outside. But it was not designed just to look beautiful. The marble walls actually protect some of the rarest books and manuscripts in the world from direct sunlight that could slowly destroy them over time. 📚