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[- @Its_LSI]

Friends, @FreiburgiGEM cooked so hard with this video it's nuts. Please give us some feedback 🥳😊 https://t.co/j00JRG9qUV

[- @Its_LSI]

time to leave this n4zi hell hole for good

[- @Its_LSI]

Weekly reminder you should move over to bluesky, the community is thriving there

[- @Its_LSI]

I hope all of us get to migrate away from this hell site as soon as possible. Something that helped me quite a bit was using the "Sky Follower Bridge" addon to find all the people I follow on here on BlueSky. Place seems pretty populated :)

[- @Its_LSI]

@Prokaryota FREE THEM!

[Lena Steckelberg @LenaSteckelberg]

I finally took the first step to leave this site! Let’s build a better science community at 🦋

Anyone excited about #RNA, #viruses and building a more supportive environment in academia, please find me there (same handle). See you on the other side.

[Dr. Lutz Böhm @DrLutzBoehm]

Oh Mann, oh Mann... 🤦‍♂️
https://t.co/kVnF6yOU3J

[dianna haze @diannahaze]

Has anyone compiled a list of all the organ systems we have evidence that COVID damages?

I’m essentially looking for something to give my (evidence curious) friends to tell them why it’s SO crucial to avoid getting COVID.

[- @Its_LSI]

@ATinyGreenCell @hsalis I miss the shared Google docs file

[- @Its_LSI]

@DrLutzBoehm @MonsterEnergyDE Die wichtigere Frage ist doch: Darf ich mit dem Wasser einen Autoklaven betreiben?

[Dr. Lutz Böhm @DrLutzBoehm]

@starkwatzinger Wir haben uns drei Jahre lang eine Forschungsministerin geleistet, die ihren Job nicht gemacht hat.
Das schaffen wir schon auch noch.

[- @Its_LSI]

Fucking finally. That took waayyyy too long

[Bettina Stark-Watzinger @starkwatzinger]

Mit dem heutigen Tag endet meine Tätigkeit als Bundesministerin für Bildung und Forschung. Die Arbeit war fordernd, aber auch zutiefst erfüllend. Ich empfinde es als große Ehre und Privileg, dass ich dieses besondere Amt nahezu drei Jahre lang ausüben durfte.

[- @Its_LSI]

@barbara_synbio I mean 🟦☁️ is still an option

[CIBSS @CIBSS_UniFR]

🌱 Big news! #CIBSS speaker @KleineVehnLab and an international team of scientists were just awarded an #ERCSynergyGrant for their project #STARMORPH! They’ll uncover plant morphogenesis paving the way for #PlantGrowthEngeneering: https://t.co/d7u7vGgCKk

[- @Its_LSI]

Cooked with this one, ngl

[- @Its_LSI]

@FreiburgiGEM Truly excited about what the new year has in store! 👀

[GASB SynBio @gasb_synbio]

We are proud to see the immense success German teams had this year🏆. This again proves how #SynBio is at the heart of Germany's #NextGen academics and entrepreneurs📈.
To celebrate, we have compiled the achievements of this years #iGEMGermany!🎉

[Javier Santoyo @jsantoyo]

KEGG: biological systems database as a model of the real world. #KEGG @NAR_Open
https://t.co/1yibH6NZPO

[- @Its_LSI]

@fiona_chembot @JCIM_JCTC That cover art is peak 🥹

[whimsy lohan (in NYC) @SexyLikeMeiosis]

CHONKUS

[Niko McCarty. @NikoMcCarty]

First a digitized scent.

Then, a paper in Nature shows how odorant receptors can be engineered to figure out how slightly different structures can recognize very distinct molecules.

This is the start of something big. I can...smell it.

[Niko McCarty. @NikoMcCarty]

A couple years ago, I wrote that plant synthetic biology is ~15 years behind microbial efforts. But now, the gap seems to be closing.

For a new paper, researchers used integrases to record gene expression events in Arabidopsis, with single-cell resolution, to study how these plants develop from seed to maturity.

This isn't the first paper to report a "memory switch" for plants (that happened back in 2020), but this paper does take it quite a bit further.

The authors use two different integrases to track two different genes involved in lateral root development, called AHP6 and GATA23. The integrases enable them to figure out which gene turns on FIRST, and in which cells. They also did a similar experiment to study stomatal development.

The integrases can trigger four different states: In state 0, cells express a blue fluorescent protein; this indicates that neither of the genes have yet been expressed.

Now, if gene #1 is activated, one of the integrases switches on and makes the cells glow red. If the second gene is activated AFTER this event, then the second integrase also switches on and the cells glow green.

If gene #2 is expressed before gene #1, however, the integrase instead makes an excision in the genome and the cells don't glow at all.

By looking at how various cells in the plant glow, in different colors, scientists are able to figure out which genes are turned on which order. Cool stuff. I'm sure this can be scaled up, and more integrases can be added, to study even more genes in parallel.