J. Michael Ryan, MD

Neuroscience Drug Developer, Geriatric Psychiatrist & Entrepreneur

[STAT @statnews]

“American science is too valuable to be turned into a political football,” writes David J. Skorton, president of the Association of American Medical Colleges. https://t.co/YXyinSj3md

[ProPublica @propublica]

New: Researchers at Stanford University modeled how many people could die or be disabled in 25 years if vaccines for polio, measles, rubella or diphtheria were no longer available. https://t.co/UD5CqAr17X

[J. Michael Ryan, MD @JMichael_Ryan]

Novo Nordisk says Semaglutide Alzheimer's clinical trial fails https://t.co/mG1PDBtgAb

[J. Michael Ryan, MD @JMichael_Ryan]

Safety, Tolerability, Pharmacokinetics, and Brain Target Occupancy of the OGA Inhibitor ASN90 in Healthy Participants - Pokorny - Movement Disorders - Wiley Online Library https://t.co/MasKqwnDc9

[Sheryl Gay Stolberg @SherylNYT]

OOPS! UPDATE: Two HHS officials tell me that disease detectives, measles response officers, Ebola response officers, global health officials and MMWR staff were laid off by mistake and will be reinstated. But Washington staff is still RIFed.

[Washington Post Opinions @PostOpinions]

"China has no scientific edge over the United States," @ScottGottliebMD writes.

"China has only a policy edge, which derives from its deliberate economic strategy." https://t.co/z0KASOESbS

[JAMA Neurology @JAMANeuro]

Frontotemporal #dementia is comparable in frequency to dementia with Lewy bodies and occurs at higher rates than progressive supranuclear palsy, corticobasal syndrome, and amyotrophic lateral sclerosis. https://t.co/gYgkhvUS54

[Dr. Tom Frieden @DrTomFrieden]

I joined eight former CDC directors—spanning Republican and Democratic administrations—to share this warning: our nation’s health is at risk. 

The very systems that protect us from disease, cancer, and future health threats are being dismantled. https://t.co/PIHGQW13BN

[Alzforum @alzforum]

A new generation of brain shuttles that use receptors other than TfR, or in addition to it, are making preclinical headway, as reported at #AAIC25. https://t.co/9YXDEd8OUt

[Alzforum @alzforum]

Plasma p-tau217 peaks at birth, according to new research. Levels in newborns surpass even those of people with Alzheimer’s. @goteborgsuni https://t.co/tAEtBAt3OS

[The Washington Post @washingtonpost]

More than 90 scientists at the National Institutes of Health signed a letter in protest of Trump administration policies they say are harming people’s health, in a rare sign of open resistance by career government employees. https://t.co/QXqahkWEoX

[Alzforum @alzforum]

Trontinemab continues to post low ARIA and fast amyloid removal, along with favorable fluid biomarker changes. Phase 3 to start this year. @adpdnet https://t.co/IK5k1bguYS

[Alzforum @alzforum]

A large epidemiological study suggests that vaccination against shingles reduces a person’s chance of getting dementia by as much as 20 percent. @Stanford https://t.co/t8elW3A7kc

[Alzforum @alzforum]

In brains of people immunized against Aβ, postmortem omics reveal microglial plaque clearing pathways. @NorthwesternU https://t.co/aKkrYJUioJ

[Alzforum @alzforum]

Can plasma tau stage Alzheimer’s? At the @HAIconference, in Puerto Rico, scientists linked up blood biomarkers with PET scan results. https://t.co/gODw65rsiv

[STAT @statnews]

The drastic reduction in indirect costs is not a path to innovation or cost savings — it’s a threat to U.S.’s position as global leader in medical research. https://t.co/vqorX6iFdi

[JAMA @JAMA_current]

Private equity acquisitions of US hospitals have increased over the past decade, and such acquisitions were associated with a worsening of patient care experience compared to non-acquired hospitals.

https://t.co/bN366fehM1

[J. Michael Ryan, MD @JMichael_Ryan]

Why Health Insurance Feels Like A Scam: Paying More And Getting Less https://t.co/qfS8guBmXB

[AbbVie @abbvie]

NEWS: @aliadatx is now part of AbbVie. This #acquisition expands our neuroscience pipeline with an investigational therapy in #Alzheimers disease and a novel blood-brain barrier-crossing technology. Read more: https://t.co/A2LWpGAHaL $ABBV

[Alzforum @alzforum]

Plasma tests for p-tau217 meet criteria for AD diagnostics. Vendors are filing for FDA approval. @Roche @EliLillyandCo https://t.co/s6pPE5djCN