JNCC

Journal of the National Cancer Center (JNCC), is a journal on all areas of cancer research launched by the National Cancer Center of China. Welcome Submission!

[JNCC @JNCC33870745]

This Review summarized current mechanistic and clinical evidence supporting the role of green tea in suppressing the progression of premalignant lesions, with a specific focus on its ability to modulate the epithelial-mesenchymal transition. Read more: https://t.co/yNMteP5dJF

[JNCC @JNCC33870745]

This Review summarized the current diagnostic approach for Epstein-Barr virus-associated lung carcinoma (EBVaLC), and integrated the clinical and biological insights into EBVaLC. Read more: https://t.co/zaynpHpU7Q

[JNCC @JNCC33870745]

This research revealed an epigenetic-metabolic circuit wherein CDK13-mediated nuclear pore reprogramming via KDM2A phosphorylation and NUP93 activation drives cholesterol metabolism and metastasis in pancreatic ductal adenocarcinoma (PDAC). Read more: https://t.co/UkgfMGjojB

[JNCC @JNCC33870745]

This study elucidated the mechanism of the XPO1-RNF5-DNAJA1 axis in regulating the sensitivity of Selinexor in the treatment of relapsed or refractory multiple myeloma. Read more: https://t.co/T3k6ax4SRr

[JNCC @JNCC33870745]

This review clarified how circuit activity and neuroregulatory programs become selectable components of tumor evolution and highlighted emerging opportunities to therapeutically target neuro–tumor axes in cancer. Read more: https://t.co/9tY9QKJ7Vv

[JNCC @JNCC33870745]

This review synthesized the established knowledge of tumor innervation with the broader hallmarks of cancer to delineate the reciprocal interplay and key messengers between cancer cells and nerves. Read the full text: https://t.co/mOC7L5bKPv

[JNCC @JNCC33870745]

This review focuses on the bidirectional interaction between neurons and malignant glioma cells, highlighting its clinical relevance and potential to guide the development of novel precision therapies specifically targeting the glioma-neuron crosstalk. https://t.co/SwEc9qhIgw

[JNCC @JNCC33870745]

The latest cancer statistics in China revealed that an estimated 5,150,000 new cancer cases and 2,580,000 cancer deaths occurred in the country in 2024. Read the full text: https://t.co/EbHEG4tv2s

[JNCC @JNCC33870745]

This systematic review and meta-analysis compared the efficacy of Chinese-developed versus imported PD-1/PD-L1 inhibitors in first-line combination therapy for advanced NSCLC. Read the full text: https://t.co/63oatg4y1F

[JNCC @JNCC33870745]

This study integrated circulating tumor DNA, genomic, and transcriptomic data to answer how to identify the most suitable advanced NSCLC patients for local consolidative therapy (LCT). Read the full text: https://t.co/JPHYFBjdeO

[JNCC @JNCC33870745]

This study identified tunneling nanotube-mediated mitochondrial transfer as a previously underappreciated mechanism driving tumor-associated macrophage metabolic and phenotypic reprogramming in head and neck squamous cell carcinoma. Read the full text: https://t.co/s2v7H1x3zq

[JNCC @JNCC33870745]

This multicenter phase II trial aimed to evaluate the orelabrutinib, fludarabine, cyclophosphamide, and obinutuzumab (OFCG) regimen as first-line therapy for patients with chronic lymphocytic leukemia. Read the full text: https://t.co/5DOhMaicSH

[JNCC @JNCC33870745]

This prospective study documented the demographic, clinical, and CT imaging characteristics of a large cohort of pulmonary nodule patients from 23 hospitals across 16 provinces in China. Read more: https://t.co/bxIrrIeagc

[JNCC @JNCC33870745]

The review focuses on dormancy of disseminated tumor cells, highlights recent advances in both cell-intrinsic and -extrinsic regulators of cancer dormancy, and reveals the microenvironment that drives the awakening of cancer dormancy. Read more: https://t.co/tEY5FQPlEV

[JNCC @JNCC33870745]

This study demonstrated sapogenin-based nanoscale assemblies as a safe and effective small-molecule platform for immunogenic cell death-driven in situ vaccination against metastatic cancers. Read the full text: https://t.co/1cRkUNKWM2

[JNCC @JNCC33870745]

This study provided an updated global assessment of esophageal and gastric cancers incidence by histological subtype and anatomical subsite utilizing data from GLOBOCAN 2022 and Cancer Incidence in Five Continents Vol. XII (2013-2017). Read the full text: https://t.co/KbKdOEXFTw

[JNCC @JNCC33870745]

This study revealed that irreversible electroporation ablation on pancreatic cancer can trigger the antitumor immune response by activating the NLRP3 inflammasome pathway, but without rigorous specificity. Read the full text: https://t.co/OnIC9K6zpP

[JNCC @JNCC33870745]

This study characterized the global disease burden of early-onset cancers in women, encompassing temporal trends, regional disparities, risk attribution, and future projections. Read the full text: https://t.co/a1zYfY1dg0

[JNCC @JNCC33870745]

This review elaborated the role of circadian disruption, sleep dysregulation, lifestyle factors, and metabolic reprogramming in the pathogenesis and progression of ovarian cancer. Read more: https://t.co/cxyQThajby

[JNCC @JNCC33870745]

This study evaluated the temporal trends and evolving patterns in liver cancer mortality in China, focusing on subnational disparities and shifts in disease burden. Read the full text: https://t.co/R3T1oUi5fz