James P. Falese, PhD

Postdoctoral fellow at NIEHS | Former biochemistry graduate student at Duke University | RNA structure and recognition | Views are my own

[National Human Genome Research Institute @genome_gov]

We’re still in our BRAT summer by sharing our new RNA resources! Improved understanding of RNA over the years has led to huge developments, such as creating a COVID vaccine that saved millions of lives. Learn more in our new fact sheet! https://t.co/f0bpvxV1ov

[Amanda Hargrove @hargrovelab]

@JPFsci You can read more on @JPFsci 's lncRNA work on @biorxivpreprint and in his thread below! His work on prostate-cancer associated SChLAP1 includes both detailed 2nd structure analysis and some cool insights into conservation and retroviral insertions!
https://t.co/R8kvEpBY8V

[James P. Falese, PhD @JPFsci]

We are currently continuing our efforts to learn more about SChLAP1. I am hugely grateful for the co-authors I share this work with @hargrovelab

[James P. Falese, PhD @JPFsci]

I’m so excited to share our updated work on structural characterization of the lncRNA SChLAP1, currently available as a pre-print on bioRxiv. A thread below

https://t.co/Rj0Am9WOGd

[James P. Falese, PhD @JPFsci]

Ultimately, our data suggest that these insertions may function alongside non-retroviral regions within SChLAP1 to facilitate prostate cancer metastasis.

[Amanda Hargrove @hargrovelab]

And yes, that's THREE HLab PhD's in 10 days!!! 🍾🍾🍾 Congrats again to Justin, Emily, and James!

With @KamillahKassam, I will have the honor of hooding 4 wonderful PhD scientists and people in May. Perfect example of why I love this crazy job.

[Amanda Hargrove @hargrovelab]

Friday we celebrated Dr. James Falese @JPFsci , HLab PhD #13! 🍾🍾James has been bravely leading our first lncRNA structure-function project for the last few years and made chemical probing a standard assay in the lab. Look for more exciting news from James very soon!

[Martina Zafferani, Ph.D. @MartinaZaffera1]

It was an absolute blast to present at @ASMBS with @JPFsci and share my science. First presentation as a Doctor!! 👩‍🎓@DukeChemistry #RNA #AcademicTwitter

[ASBMB @ASBMB]

A spotlight session on noncoding RNAs starts in half an hour, with talks on lncRNA structure and regulatory roles, and the non-coding transcriptome in sugar-challenged kidneys.

https://t.co/VWn1nRTInn

Featuring @JPFsci, @MartinaZaffera1, Nik Tsotakos and Subhrangsu Mandal.

[James P. Falese, PhD @JPFsci]

So excited for this work to be out in the world. Our work on the secondary structure of SChLAP1 is out now on #bioRxiv @hargrovelab @emjmcfadden

[Amanda Hargrove @hargrovelab]

The lab had a pandemic's-worth of milestones to celebrate, so we did them all at once! 🍾🥳Congrats to PhD candidates @Jgmartyr @JPFsci @KamillahKassam and Emily Swanson (#whoneedstwitter) and to @MartinaZaffera1 @cai_zhengguo for passing their prop exam! Papers party soon!🧪📜🎉

[James P. Falese, PhD @JPFsci]

@emjmcfadden Ew Nature!

[James P. Falese, PhD @JPFsci]

@emjmcfadden @TehshikYoon 1000% we’re making this happen

[Nathan O. Hatch @PresidentHatch]

It has been the adventure of a lifetime to lead @WakeForest with you.