JPN

JPN publishes original research and review papers that build an understanding of the mechanisms involved in etiology and the treatment psychiatric disorders.

[JPN @JPsychNeurosci]

This account is no longer being updated.

[JPN @JPsychNeurosci]

Early treatment response in patients with panic disorder:
The temporal variability in the insula and lingual gyrus are potential biomarkers for the treatment of panic disorder. ⬇️ https://t.co/0rvrGoQAy6

[JPN @JPsychNeurosci]

In a large MRS study, reduced glutamatergic tone was observed in early high-risk states of schizophrenia, which likely increase as symptoms intensify:
Glutamate levels and symptom burden in high-risk and first-episode schizophrenia ⬇️ https://t.co/sLIOByWw1Y

[JPN @JPsychNeurosci]

Use of extraretinal information and psychosis:
Impaired corollary discharge signalling may be a marker of predisposition for psychosis. ⬇️ https://t.co/TOjO3UWv9F

[JPN @JPsychNeurosci]

Disorder-specific and transdiagnostic alterations in decision-making:
The study reveals altered decision-making in MDD, OCD and schizophrenia, linking reduced model-based behavior to depressive symptoms and anhedonia. ⬇️ https://t.co/GgF6vIkjHW

[JPN @JPsychNeurosci]

Metabolites in peripheral T lymphocytes and ketamine-induced schizophrenia:
A ketamine-induced schizophrenia mouse model showed increased peripheral CD3+ T cells and disrupted amino acid metabolism pathways ⬇️ https://t.co/8TcKQRDRNw

[JPN @JPsychNeurosci]

Neuroscience education for people with addiction may be a way that preclinical and fundamental neuroscientists can engage in transdisciplinary scholarship through community outreach activities that support people with lived experience. ⬇️ https://t.co/dKRhE0Shkk

[JPN @JPsychNeurosci]

Metabolites in peripheral T lymphocytes and ketamine-induced schizophrenia:
A ketamine-induced schizophrenia mouse model showed increased peripheral CD3+ T cells and disrupted amino acid metabolism pathways. ⬇️ https://t.co/8TcKQRDRNw

[JPN @JPsychNeurosci]

Effective connectivity and automatic smoking behaviour:
Aberrant causal connections of different functional subsystems of the default mode network are present in tobacco use disorder. ⬇️ https://t.co/p3Gro1StN7

[JPN @JPsychNeurosci]

Polygenic risk for depression and resting-state functional connectivity:
Genetic risks for depression affect subgenual anterior cingulate connectivity in young adults ⬇️ https://t.co/C5TIIgSSyD

[JPN @JPsychNeurosci]

Intrinsic neural timescales of the self in schizophrenia:
Schizophrenia is characterized by reduced and less adaptable intrinsic neural timescales, highlighting disruptions in self-processing and temporal integration. ⬇️ https://t.co/PZwZOAO7vo

[JPN @JPsychNeurosci]

Systemic inflammation is likely involved in the mechanism of early white matter injury among patients with cerebral small vessel disease. ⬇️ https://t.co/L6NhtHjcev

[JPN @JPsychNeurosci]

Depression as a speed disorder:
Instead of looking for markers specific to each symptom domain of MDD, identify a feature that links and is common to all symptoms across their different domains. ⬇️ https://t.co/jyilbDBJph

[JPN @JPsychNeurosci]

Structural-informed fMRI of patients with empathy impairment following stroke:
Reduced empathy following stroke was strongly associated with a more severe cognitive profile and atrophy of the right cingulate cortex. ⬇️ https://t.co/wZmIqMTpTB

[JPN @JPsychNeurosci]

Hyperactivity and hyperactivity in brain regions of patients with depression were associated with emotional experience and cognitive control, respectively, during the use of emotion regulation strategies. ⬇️ https://t.co/s4a9rYDWh6

[JPN @JPsychNeurosci]

Polygenic risk scores of depression and cortical morphology networks:
Cortical morphometric networks in people with depression and those with high genetic risk highlighted connectivity of the SMN and DMN. ⬇️ https://t.co/snRpaT4Ixg

[JPN @JPsychNeurosci]

Depressive symptoms may cause abnormalities in the hierarchical segregation of functional brain organization among patients with MCI, which may be related to the distribution of neurotransmitters. ⬇️ https://t.co/rWsJzc2GoC

[JPN @JPsychNeurosci]

2024 CCNP award winners:
The CCNP announces the winners of its Innovations in Neuropsychopharmacology, Young Investigator, and Heinz Lehmann awards and the CCNP Medal for 2024. ⬇️ https://t.co/svTuL8E6OY

[JPN @JPsychNeurosci]

Mechanisms of clozapine-induced cardiac arrest:
Potential mechanisms by which clozapine may cause cardiac arrest include the MAPK cascade, neuroactive ligand–receptor interactions, and the FoxO signalling pathway. ⬇️ https://t.co/xRfcjkyj9x

[JPN @JPsychNeurosci]

MicroRNA profiling in adolescents offers great promise in addressing the urgent need to identify young people who are at risk for developing psychiatric illness and to begin to understand the underlying psychopathology at the molecular level. ⬇️ https://t.co/MNr9OQHXul