JU Open Plus

Official journal of @Amerurological. Your source for open access urology research: original studies, reviews, videos & more. Submit, read, share!

[JU Open Plus @JUOpenPlus]

📢 The May Issue of JUOP Is Here

From insights shared at the 2026 EAU Congress to emerging treatment strategies across kidney, bladder, and prostate cancers, this issue explores how the field continues to evolve. Highlights include advances in systemic therapies for advanced renal cell carcinoma, new thinking around protecting cardiovascular health in prostate cancer care, and innovative approaches to managing high-risk bladder cancer when standard therapies fall short.

Stay at the forefront of urologic oncology research and clinical innovation, click the link below to read the issue now!

🔗 https://t.co/1wnmZnyOge

[JU Open Plus @JUOpenPlus]

Can artificial intelligence help close the gap in prostate cancer detection using microultrasound?

In this article, the authors develop and evaluate a deep learning model to detect clinically significant prostate cancer and assess its impact on novice readers. They show that AI—especially when combined with training—can improve diagnostic performance and support more accurate clinical decision-making.

🔗 Click to read more: https://t.co/QFQ5tuh889

[JU Open Plus @JUOpenPlus]

Does surgical technique choice impact both cancer outcomes and cost in prostatectomy?

In this article, the authors compare oversewing versus stapling of the dorsal venous complex during robotic prostatectomy, finding similar oncologic and postoperative outcomes between approaches. They also highlight a significant cost advantage with oversewing, offering important considerations for surgical decision-making.

🔗 Click to read more: https://t.co/j1IFUWpXg8

[JU Open Plus @JUOpenPlus]

What does it take to move beyond the limitations of traditional urinary diversion?

In this comment, the author examines the balance between the proven benefits and significant complications of gut-based bladder reconstruction while exploring innovations like tissue engineering and transplantation.
It also highlights the key challenges and ethical considerations shaping the future of bladder replacement.

🔗 Click to read more: https://t.co/GXXoy8Gk3F

[JU Open Plus @JUOpenPlus]

What if bladder reconstruction didn’t have to rely on intestinal tissue and its complications?

In this article, the authors review current urinary diversion techniques and emerging innovations like tissue engineering aimed at improving outcomes. They also outline key challenges that must be addressed to advance safer, more effective bladder replacement options.

🔗 Click to read more: https://t.co/yawkX3oFq2

[JU Open Plus @JUOpenPlus]

The April issue of JU Open Plus is here! Explore the latest in open access urological research—available to read now and free to all. As a “gold” Open Access journal, every article is immediately accessible without restrictions. 📚

🔗 Click the link to read the amazing articles today: https://t.co/1wnmZnyOge

[JU Open Plus @JUOpenPlus]

The bladder doesn’t exist in isolation.

This letter argues that urinary health reflects an interconnected gut–vagina–bladder axis, shaped by diet, environment, hormones, and antibiotics—suggesting cranberry’s effects on the urobiome may be indirect and reinforcing the need to move beyond organ‑centric thinking in urology.

🔗 Click to read more: https://t.co/BfWb1zFiZL

[JU Open Plus @JUOpenPlus]

Prostate cancer risk assessment must keep pace with imaging advances.

This editorial underscores the value of spatial tumor burden from MRI‑fusion biopsy, arguing that metrics like cancer‑involved regions offer deeper biological insight than traditional measures—and should play a larger role in guiding treatment decisions.

🔗 Click to read more: https://t.co/cm0TFqVftV

[JU Open Plus @JUOpenPlus]

Can prostate biopsies predict surgical risk more accurately? 🔍

New research shows that counting cancer‑involved regions on MRI‑fusion biopsy helps identify patients at higher risk of adverse pathology after prostatectomy—offering a smarter way to guide treatment decisions in the MRI era.

🔗 Click to read more: https://t.co/71HDbpQTSx

[JU Open Plus @JUOpenPlus]

Equity remains the missing piece in kidney cancer care.

This editorial stresses that persistent racial and ethnic gaps in partial nephrectomy and robotic surgery are driven by insurance, socioeconomic barriers, and where patients receive care—underscoring the need for systemic fixes, not just advanced technology.

🔗 Click to read more: https://t.co/nmHi2KxnEC

[JU Open Plus @JUOpenPlus]

Who gets access to the most advanced kidney cancer surgeries—and who doesn’t?

A new national study shows Black and Hispanic patients are less likely to receive robotic-assisted and kidney-sparing surgery for renal cell carcinoma, even as these options become standard across tumor stages. Medical innovation is advancing—but equitable access is not keeping pace.

🔗 Click to read more: https://t.co/tezDHSNbzu

[JU Open Plus @JUOpenPlus]

🚀 Space changes more than gravity—it may reshape the urinary microbiome.

This editorial highlights early evidence that spaceflight alters urinary microbiota, while underscoring the real takeaway: small, short‑mission studies are just the start. Longer missions, chemical + microbiome analysis, and greater inclusion of female astronauts are critical to understanding long‑term health risks in space.

🔗 Click to read more: https://t.co/lTuodb9QXw

[JU Open Plus @JUOpenPlus]

🚀 What happens to the urinary microbiome in space?

New research from a short ISS mission shows spaceflight significantly alters urinary microbiota—changes that reverse after return to Earth—raising important questions about astronaut health on future missions.

🔗 Read more: https://t.co/NFs8xgcZdl

[JU Open Plus @JUOpenPlus]

Rethinking dysfunctional voiding treatment in young men.

This editorial highlights a key shift: pairing pelvic floor physical therapy with baclofen shows promise in improving voiding by better relaxing the pelvic floor—but stresses the need for randomized trials to confirm whether medication truly adds benefit beyond therapy alone.

🔗 Click to read more: https://t.co/CM1Z3DaDir

[JU Open Plus @JUOpenPlus]

Trouble voiding in young men doesn’t have to mean invasive care.

New research shows a conservative combo—oral baclofen plus pelvic‑floor muscle training—significantly improves symptoms and urinary flow in young adult men with dysfunctional voiding, with no major safety concerns.

🔗 Click to read more: https://t.co/IhAZRmrALz

[JU Open Plus @JUOpenPlus]

The November issue of JU Open Plus is here! Explore the latest in open access urological research—available to read now and free to all. As a “gold” Open Access journal, every article is immediately accessible without restrictions. 📚

🔗 Click to read the amazing articles today: https://t.co/1wnmZnyOge

[JU Open Plus @JUOpenPlus]

📊 Who’s shaping the future of urology fellowships?

New AUA match data (2014–2025) show a marked rise in women matching into urology subspecialty fellowships—driven by oncology, endourology, and reconstructive surgery—while trends vary by subspecialty, highlighting where progress is accelerating and where gaps remain.

🔗 Click to read more: https://t.co/8TIZaf4OIa

[JU Open Plus @JUOpenPlus]

A routine lab value may be quietly shaping surgical recovery.

Thank you @BogdanaSchmidt for your insights into, "Serum Albumin Levels Are Independently Associated With Length of Stay and Readmission in Patients With Renal Cell Carcinoma" which highlights how lower preoperative serum albumin independently predicts longer hospital stays and higher 90‑day readmission risk—highlighting nutrition as a powerful, actionable factor in perioperative care.

🔗 Click to read more: https://t.co/Ja3xGNzftn

[JU Open Plus @JUOpenPlus]

❤️ Heart health matters in prostate cancer care.

New real‑world data show men starting ADT with diabetes, hypertension, or high cholesterol—especially all three—face a sharply higher risk of cardiovascular events. A simple comorbidity check could help flag risk before treatment begins.

🔗 Click to read more: https://t.co/ymIawcp1vm

[JU Open Plus @JUOpenPlus]

Better biomarkers—now what about MRI?

This editorial underscores that combining blood (Phi) and urine (PCA3 + TMPRSS2:ERG) biomarkers improves detection of clinically significant prostate cancer—but emphasizes the next step: integrating these tools with pre‑biopsy MRI to better target who truly needs a biopsy.

🔗 Click to read more: https://t.co/cm2oNklKKj