Jacob Fredegaard Hansen

AI in drug design and discovery. Educating next gen of drug and data bilinguals at @UCPH_Research 🧬👨‍💻

[baSeq @baSeqbio]

The CRF2 (also known as CRFR2 and CRHR2) agonist landscape in obesity: 8 molecules in the Atlas database.

4 in Phase 1 (Gubra, Neurocrine, Hanmi, Corteria), 4 with just a patent. All UCN2 analogs. Big pharma still on the sidelines via filings only.

$GUBRA $NBIX $NVO $LLY $SAN

[baSeq @baSeqbio]

The INHBE obesity landscape, 36 molecules in the Atlas database.

9 in Phase 1, 9 preclinical, 18 at patent stage. siRNA dominates. China leads on filings, US leads on clinical.

$ARWR $WVE $ALNY $LLY $AMGN $REGN

[Vedel @vedel_j]

$RVMD $ERAS $ANL. Credit: https://t.co/kwxU2R9jRZ

[Jacob Fredegaard Hansen @Jacobfh]

Enjoying the @iGEM Jamboree in Paris. Super happy to have had great products from @idtdna to help the team through the iGEM Competition! 🧬🧪🧫

[Jan Kosinski @jankosinski]

This is unreal! 🤯An AI-generated podcast about our AI-created model of the human nuclear pore complex. Whether you're a scientist or not, you have to hear this! Sound on! 🔊

[Luciano Abriata @labriataphd]

Acting on a piece of folded RNA (@PDBeurope 6D3P) with my hands in #AugmentedReality using a @MetaQuestVR 3, backed up by @openmm_toolkit running an @ambermdprog forcefield.
All web and accessible to you in some months hopefully!
By @fabiojcortes and @lucien_krapp :-)

[Jakob Møller-Jensen @JMollerJensen]

Hold igen med kage til aftenkaffen! Min kollega Lars Grøntved @Grontved_Group deler spændende viden om døgnrytmens effekt på vores stofskifte: https://t.co/VCUIe7uZsr

[Nature Biotechnology @NatureBiotech]

Drug discovery is being transformed by advances in computational protein structure prediction and protein design https://t.co/tWCGv6Xv49
https://t.co/6pLKyGuKp4

[Greg Brockman @gdb]

Announcing Sora — our model which creates minute-long videos from a text prompt: https://t.co/SZ3OxPnxwz

[David Perell @david_perell]

Remember this for whenever you design something.

[Tim Cook @tim_cook]

Mac changed everything when it was introduced 40 years ago, and through the years it has done so again and again and again. Today’s Mac lineup is the best in the history of the personal computer, and it’s built on decades of revolutionary innovation. Happy birthday Mac!

[tom ッ @tom_antok]

End of the programmer's day

[Tim Cook @tim_cook]

Thank you to @rasmusbrohave for showing me around Copenhagen and its beautiful historic canal in Nyhavn!

[SDU iGEM @SDU_iGEM]

NIC was a great event, and we have gotten a lot of positive feedback. Congratulations to ABOA for winning the presentation contest and honor of hosting NiC next year🥳 but all the teams had great projects and we are looking forward to hear more about them in Paris.
#iGEM #SDU

[Anne Loft @AnneloftSdu]

📣Job Alert! Are you a curious and ambitious student looking for exciting opportunities? 🔍 Join my or @FiskerSchmidt dynamic teams and become part of an international & collaborative environment at @ATLAS_SDU @GenomicsUnit @NATSDU

https://t.co/Akk5XUci5Z

Please RT #sciencejobs

[Rowan Cheung @rowancheung]

Proper ChatGPT prompting has saved me hours of work.

This is an opportunity of a lifetime, take advantage of it.

Here are the top 5 prompts that I use every day:

[Jakob Møller-Jensen @JMollerJensen]

Vigtig diskussion om stamcelleforskningens perspektiver og potentielle faldgruber på ⁦@tv2newsdk⁩. Min kollega Helle Bogetofte Barnkob deler sin ekspertviden 👏 ⁦@NATsdu⁩ ⁦@bogetofte⁩ ⁦@bmbSDU⁩

[SDU Science @NATsdu]

Nyopdaget virus har fået navnet Fyn8. Den kan bekæmpe Pseudomonas aeruginosa, der ligesom mange andre bakterier har udviklet resistens mod antibiotika og nu findes på hospitaler @ClareLKirkpatr1 #Fyn
https://t.co/or703qJuyU

[Jesper Madsen @jespergrud]

Are you tired of setting thresholds on the total number of UMIs, the fraction of UMIs derived from mitochondrial genes, etc., when you're QC'ing single-cell/nucleus RNA-seq? We were! So we designed valiDrops, which is now out as a preprint.
https://t.co/89cwAev1c2
Thread 👇

[Helle Bogetofte Barnkob @bogetofte]

Come join our amazing protein research group @bmbSDU for a 2-year postdoc in neuroproteomics studying neurological diseases using stem-cell derived neural organoids 🧠
https://t.co/dspq7n0rs9