Jan Prochazka

Science and experimental farming with more or less succcess to achieve things normal for our ancestors

[Jan Prochazka @JanProchazka18]

@Vedazije A chápete to vy?

[Institute of Biotechnology @IBT_CAS]

🧬In a collaborative study led by @CZphenogenomics and @imgprague , we discovered that the scaffolding protein CUL4A can suppress cancer development in the colon by regulating intracellular signaling. This finding challenges the commonly held view of CUL4A as a cancer-promoting factor in other tissues.
🔎Our team @BarinkaLab at #IBT contributed recombinant enzymes and biochemical expertise that helped clarify this regulatory pathway. These insights deepen our understanding of how protein networks maintain intestinal health - and how their disruption may lead to cancer.
@BIOCEV_science @CzechAcademy
📖 Read the full study in Cancer Letters 👉 https://t.co/BLmsTILXlk

[jana.balounova @balounova_jana]

Happy International Day of Immunology from ⁦@CZphenogenomics⁩! #DayofImmunology ⁦@CYImmunologists⁩ ⁦@imgprague⁩

[Jan Prochazka @JanProchazka18]

@SvobodaLab Nechceš očkovat slimáky, že ne? Zrovna dělám sadbu

[Jan Prochazka @JanProchazka18]

@SvobodaLab A draci jsou letos taky dříve

[Jan Prochazka @JanProchazka18]

@SvobodaLab Dneska babocka paví oko 🤷

[Dominik Hasek @hasek_dominik]

If I were to walk outside with my small children and people around me were shouting "Slava Ukraine," I would be proud of my fellow citizens for supporting a defending country that was being attacked by a terrible enemy that kills there every day. And I would try to explain to my children that children like them are being killed and maimed there every day by Russian bombs. And that is why we must help and support Ukraine. It is hard for me to understand that in this case you are not proud of your fellow citizens and that you will not take the opportunity and try to explain to your children what terrible crimes Russia is committing in Ukraine. And even on children like yours.

[Petr Pavel @prezidentpavel]

The time has come to start considering a broad coalition of willing for just peace in Ukraine. “Peace” on terms of the aggressor is called a capitulation and would only encourage all current and future aggressors. Free world must stand up to the evil.

[Volodymyr Zelenskyy / Володимир Зеленський @ZelenskyyUa]

Thank you for your support.

[Akademie věd ČR @Akademie_ved_CR]

☝️ Dnes je 28. února, Mezinárodní den vzácných onemocnění, který upozorňuje na důležitost vědeckého pokroku v této oblasti.

⚕️ Existují tisíce vzácných onemocnění, často ještě nedostatečně probádané, pro něž dosud neexistuje účinná léčba.

🔬 České centrum pro fenogenomiku (CCP), velká výzkumná infrastruktura při @imgprague, proto spustilo program RD-Factory, jehož cílem je zjistit více informací o těchto onemocněních, zlepšit jejich diagnostiku a pomoci najít možné způsoby léčby. Aby výzkum pokryl i nemoci, které pacienty a jejich rodiny nejvíce trápí, byla výzva k nominaci nemocí otevřena nejen odborníkům, ale i samotným pacientům a pacientským organizacím.

Více⬇️
https://t.co/jPphQJbwkN

[nature @Nature]

A two-and-a-half-year-old girl shows no signs of a rare genetic disorder, after becoming the first person to be treated for the motor-neuron condition while in the womb.

https://t.co/PpL5NeM6Go

[Jan Prochazka @JanProchazka18]

@Eva_CZ1 @EluIluvatar Jako jiné klasické desinfo....jestli máte čas a chuť tak si skutečně projděte skutečná data a nebo jen prolitnete příspěvky od Eric Topol.

[Effie Parks @OnceUponAGene]

Parents, if your child is showing signs of global developmental delay, seizures, hypotonia, spasticity, feeding difficulties, missed milestones, or microcephaly, don’t let the system waste your time.

Doctors often want to start with an MRI and delay genetic testing - but that approach can cost you valuable time, better treatment options and community.

Advocate for a Whole Exome Sequencing test first. Request the WES immediately, and while you’re waiting for the results, go ahead and schedule the MRI. The MRI is important, but it won’t give you the genetic answers you need to guide your child’s care and future treatments.

Request a WES - Nothing Less

[Lenka Benešová 🇨🇿🫶🇺🇦 🐇&🐍&🐲&👑&👤 @beneslenka]

Tak a teď ale fakt CHCI, abychom jako Česká republika definitivně odpískali členství v beztak dávno mrtvým a zbytečným projektu V4.
Nasrat Filco! Nasrat Orále! 🖕

[Jan Prochazka @JanProchazka18]

@SvobodaLab A není to málo?

[Jan Prochazka @JanProchazka18]

@bryjalab So proud od this opportunity...and with ChP it is just begining, there are so many cool things waiting for discovery 🤯

[eLife - the journal @eLife]

A novel method for imaging glutamate receptors in situ via #CryoET. https://t.co/JmacfhuLS0

[International Clinical Research Center @FNUSA_ICRC]

Pavel Krejčí, head of our Cell Signaling team and researcher at the Institute of Animal Physiology and Genetics of the Czech Academy of Sciences, has received the prestigious Praemium Academiae 2024 award from Eva Zažímalová, President of the @Akademie_ved_CR . Congratulations!

[Jan Prochazka @JanProchazka18]

@SvobodaLab But average bar in Wisconsin