If You ever asked me what are the most interesting cells in the human body, I would tell You without a doubt that it's platelets. 🥳Check out another "baby" of ours: "Platelet role in the prediction of MIS-C severity". https://t.co/rboHaODSXB @FrontPediatrics
This is important - new UKHSA study shows ⬇️ group A strep (GAS) infections in pilot areas where primary school kids were offered nasal flu vaccine during 2013-17 vs other areas where vaccine not used as widely
👉Nasal flu vaccine REDUCES the risk of group A strep infections👇
🚨Clinical Guidance released🚨
#GroupAStrep in children: Interim Summary
https://t.co/n991D0vDRg
Highlights use of Fever Pain for decision making & that antibiotic duration, given current circumstances, can be adjusted although 10 days remains optimum for microbiological cure.
What makes winter pressures so dangerous for children?
Important to realise that children presenting with fever, high heart rates and being 'unwell' are overwhelmingly likely to not have a bacterial origin to their illness.
https://t.co/oewzak88kM
https://t.co/PI5OVVpk4y
All #paediatricians see the impact of RSV and bronchiolitis. Vaccines are successful in protecting preterm babies and researchers across Europe are hoping a vaccine will cut hospitalisations in healthy term babies too #vaccineswork#vaccinessavelives https://t.co/FKzE9A7hdT
#Covid19 😷did not just affect children's and adolescents' respiratory systems.
Together with ECPCP, EAP has published an article in @FrontPediatrics on the repercussions of #Covid19 on child and adolescent #mentalhealth
Read it here 👇
https://t.co/S1RHenpaOs
1/ So, here’s some really exciting news:
The hyper-inflammatory heart condition linked with #COVID19 (MIS-C/PIMS-TS) in kids has now virtually disappeared - despite large waves of community #SARSCoV2 infections with omicron & it’s subvariants …🧵
👉 https://t.co/NHKWJscTiD
A combination of 2 vascular biomarkers can identify #LongCovid with 96% accuracy according to this study
Both ANG-1 and P-SEL are related to endothelial injury
Authors suggest angiogenesis (dev of new blood vessels) as a target for potential treatments
https://t.co/N7D8OjmHOS
Such an amazing experience in #eaps#EAPS2022. Networking, best speakers and experts, interesting talks about off-label drugs in pediatrics, pediatric dermatology, infections, surgery, pulmonology, regenerative medicine in children diseases, rare disease, AI. Best time ever!
#Covid is becoming routine. However, this is still unsolved topic for the most suitable therapy during #covid-ARDS . Especially in #children. Our new work- a hypothesis paper on #HMGB1 role in #SARS-CoV-2 #ARDS with the focus on vagal stimulation. https://t.co/syptdwPdJA
Think. Of. The. Children:
Nearly 4x as many cases as peak of Alpha wave
12+ vaccine rollout is too late, and too slow.
They are deliberately infecting our children.
And not without consequence;
child Covid hospitalisations high & rising,
and #LongCovidKids too.
#NotReassuring
The govt released a detailed comparison of children admitted to hospital between wave 1 (spring 2020) and wave 2 (winter 2021) on Friday.
Some things that stand out:
Large marjority (80%) were admitted BECAUSE of covid & almost 60% of children had no underlying conditions 1/3
Consider this excellent review on possible mechanisms for long-COVID. Some of these hypotheses may be wrong, but this paper is ideas-rich and *citation-rich*. We're not starting from scratch; at minimum, there's a trove of hypotheses to test.
https://t.co/cSEwijv09Y
How the immune system responds to a SARS-CoV-2 infection largely defines the course of the disease.
In this story for @TheScientistLLC, I focus on two things that can go wrong:
- not reacting on time ⏲️
- confounding the target (autoimmunity) 🎯
https://t.co/KoskDY3njE
A @CellCellPress commentary yesterday entitled "Keeping Pace with the #SARSCoV2 Variants" states
"The evidence so far suggests that effectiveness against hospitalizations and symptomatic illness is highly preserved against Delta" https://t.co/T8V6e5mMgF
I'm calling it out. /1