Jason Luke, MD, FACP, FASCO

Physician-Scientist-Executive & Chief Medical Officer @StrandTx

[The Cancer Letter @TheCancerLetter]

“Last year, I would say my most listened to song is the melody of the telemetry monitor in the cardiac intensive care unit alarming arrhythmias, or the lullaby of bed alarms on the floors overnight. In those few moments where I can explore new music, I’ve become quite enamored with RAYE."- Anna Crosetti
https://t.co/e0dMrtme0p

[Jake Becraft @DrSynbio]

I’m on my influencer game here. So since more people have asked:

The next frontier for AI-designed medicine is mRNA that can recognize what kind of cell it has entered and control what happens next.

At Strand, we are building that future with cell-type-specific mRNA. 🧵

1/6

[Jake Becraft @DrSynbio]

A lot of you have asked me where mRNA and AI-designed genetic medicine will go after this exciting week. A short thread seemed easier to share: 🧵

To start: @StrandTx is building the definitive mRNA therapeutic stack: off-the-shelf medicines that turn tumors into factories.

[Elon Musk @elonmusk]

@EricTopol Despite its obvious misuse during Covid, mRNA has tremendous promise for curing diseases.

Artificial RNA essentially makes curing diseases a software problem.

[Michel Doepke @doepke_michel]

$MRK and $MRNA Announce Phase 3 INTerpath-001 Trial of Intismeran Autogene Plus KEYTRUDA® Met Endpoints of Recurrence-Free Survival (RFS) and Distant Metastasis-Free Survival (DMFS) in Patients With Completely Resected Stage IIB-IV Melanoma https://t.co/BQNbqCTRex

[Adam Feuerstein ✡️ @adamfeuerstein]

🚨🚨🚨BREAKING CANCER NEWS! 🚨🚨🚨

Merck $MRK and Moderna $MRNA personalized mRNA cancer vaccine slowed the return of melanoma and its spread to other parts of the body in a Ph3 clinical trial.

No data disclosed yet, but the study was stopped for positive results at the first interim analysis.

Magnitude of benefit TBD, but this is a potentially huge breakthrough for cancer patients and the use of mRNA to treat cancer.

Read STAT's story from @matthewherper and @angRchen

https://t.co/mL02z7RyZy

[Strand Therapeutics @StrandTx]

Excited to share that Strand Therapeutics has once again been nominated in the Best Startup category for the 2026 Prix Galien USA Awards by @GalienFdn recognizing innovation advancing global health.

Congratulations to our fellow nominees, and we look forward to celebrating the advancement of science together this fall.

More info here: https://t.co/RbRCDqY3pL

[Stephen V Liu, MD @StephenVLiu]

Nature publication today from Dr. Tina Cascone et al with tremendous detail on biomarkers from CheckMate 77T predicting benefit from perioperative nivolumab in patients with resectable NSCLC. Amazing amount of detailed data in this @Nature paper.

https://t.co/Sb0H4YOpxz

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

https://t.co/SbfuWvBGCl

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

Enjoyed this review on miRNAs regulating the TME. At @StrandTx our miRNA based SignalLock tech facilitates TI expansion by de-targeting healthy organs via miR binding, so that our repRNAs only translate in the TME. Amazing all the ways that miR's are impacting drug development!

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

An amazing 2 days @sitcancer #biotech discussion @NYSE! We have an amazing community from VC, banks, pharma, small co's, academia & more. Biotech has some heavy demands yet it is an outstanding & fortunate opportunity to be able to contribute at @StrandTx amongst these colleagues

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

Was super cool to rep @sitcancer & @StrandTx for the opening bell ringing at NYSE this AM! The SITC Biotech Strategic Meeting is a tour de force of talks & panels for mtg of minds across our ecosystem. Our 100 approvals in 10 years goal is on track!
https://t.co/8Glxq1tlpR

[Strand Therapeutics @StrandTx]

Congratulations to our co-founder and CEO, @DrSynbio, on being named an @EY_US Entrepreneur Of The Year® 2026 New England Award winner!

This recognition reflects a mission that every person at Strand shows up for every day: programming mRNA to sense, decide, and act inside the body, so that therapies reach more patients, treat more diseases, and do so more scalably than ever before.

That mission is what keeps us moving forward.

[Strand Therapeutics @StrandTx]

For Cancer Immunotherapy Awareness Month, Strands participated in today's #WearWhite campaign honoring the dedication of patients, caregivers, and researchers working to improve cancer treatment

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

Congrats Bob! Looking forward to your leadership.

[Robert Ferris, MD, PhD @RobertFerrisMD]

Congratulations to our new SITC leaders! Very honored and looking forward to working with existing and future leaders, and amazing staff to help SITC continue to advance cancer immunotherapies and contribute to this amazing field. @UNC_Lineberger

[Strand Therapeutics @StrandTx]

Hard to miss Kunal Bhatia on the @Nasdaq tower in Times Square, featuring his appointment as Chief Financial Officer.

In Kunal’s words, “I joined Strand because I believe we are one of the most innovative biotech companies today; importantly, we are prosecuting a big vision with rigor and intense focus.”

Glad to have him helping lead this next chapter

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

What an amazing night! Thanks to all who came out to support @sitcancer & the goal of advancing the careers of the next gen investigators who will find cancer cures through immunology! #asco26

[Dr. Patrick Hwu @PatrickHwuMD]

After a full day of science, we’re Walking on Sunshine and taking the stage! 🎵 #TheCheckPoints are taking over @BuddyGuys. 🎤🎸

@sitcancer @FerranPrat5 @RPachynski @BReinfeld @jasonlukemd @wolchokj #ASCO26

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

@Nfcanavan @StrandTx @ASCO Tonight!

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

Best party of the year and all for a great cause! Join us at @BuddyGuys Sunday night #ASCO26 to dance, network and raise research funds to support the next gen of cancer immunotherapy researchers! The Checkpoints are ready to rock. Hope to see you there! @PatrickHwuMD @BReinfeld

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

Our team @StrandTx is excited to be at #ASCO26. Happy to meet up to discuss our transformative platforms surrounding STX-003 (IV repRNA IL-12 with SignalLock to the TME) and STX-005 (next gen circRNA in vivo CART) for B cell depletion. Come say hello!
@ASCO

[Jason Luke, MD, FACP, FASCO @jasonlukemd]

Best party of the year and all for a great cause! Join us at @BuddyGuys Sunday night #ASCO26 to dance, network and raise research funds to support the next gen of cancer immunotherapy researchers! The Checkpoints are ready to rock. Hope to see you there! @PatrickHwuMD @BReinfeld