Congratulations to our outstanding mentor, Dr. Jiang, for receiving the prestigious award from #ASBMR! Your dedication and contributions to the field are truly inspiring. Well-deserved recognition! 🎉🏆
🎉Excited to share our latest publication in Redox Biology. We uncover a novel mechanism linking Cx43 HCs mechanosensing to GSH transport, crucial for maintaining redox balance in lens. #cx43#connexin#redoxbiology#jeanjianglab
Check the link 👇
https://t.co/D8xbiZclBL
Principal Investigator Jean X. Jiang (@JeanJiangLab) pioneered the modulation of hemichannel activation using targeting antibodies. Her team at @UTHealthSA discovered two targeting antibodies: one to open the hemichannels and another to block. While other teams have been able to block hemichannels, Dr. Jiang’s team was the first to activate and open the hemichannel. “The Welch Foundation grant helps us tremendously because Welch is willing to invest in projects that could be high risk but also have the potential for very high impact, projects that would not be funded by traditional grants. One of the ways we mediate this risk is by switching approaches. Welch is terrific because they allow us to have this kind of flexibility.” Read more about Dr. Jiang and her team’s work here: https://t.co/tMShZc5aOj
🚨New paper alert in @PNASNews@JingruoZz reveals how osteocyte regulate MSC fate through connexin hemichannels & PGE2 signaling! 🔬Osteocyte connexin hemichannels and prostaglandin E2 release dictate bone marrow mesenchymal stromal cell commitment | PNAS https://t.co/j3UVL6FYWD
Exciting research from our lab! 📢 Our latest study explores the critical roles of biglycan and decorin in bone mass regulation, water retention, etc. Check it out! #BoneResearch The full text of the paper through the link: https://t.co/9LqFTOoMiD
#ASBMR2024 ASBMR is more than just cutting-edge research and innovative applications; it's a hub for brilliant minds and cherished connections.@ASBMR@JeanJiangLab
#ASBMR#ASBMR2024 Thanks to everyone who stopped by our plenary poster yesterday! We had the opportunity to engage with many incredible researchers. If you missed it, don’t worry! We will be presenting again today from 2:15–3:45 pm at Poster 505. We hope to see you there!
Great talk Dr Bruce J Nicholson, thanks for sharing!
"Gap Junctions - a window into the origins of endometriosis and a pathway to diagnosis and therapy."
Great job Dr Francisca Acosta, thanks for sharing all of your very interesting data!
"Connexin Hemichannel Opening in Osteocytes and PGE2 Release: A
Mechanism for Reducing Adiposity, Enhancing Metabolic Balance, and
Maintaining Lean Mass"
Good news from our lens group. A new published paper”Mechano-activated Connexin Hemichannels and Glutathione Transport Protect Lens Fiber Cells Against Oxidative Insults” in #RedoxBiology. Welcome to get some details for how Cx HCs regulate #oxidative#stress.
Thrilled to share our another new publication “Connexin Hemichannels Drive Lactation-induced Osteocyte Acidification and Perilacunar-Canalicular Remodeling” in #CellReports! Please check out the paper regarding how Cx HCs remodel bone matrix during lactation.#bone#lactation🎉