Jess Orr

PostDoc @ucl 👩🏼‍🔬
💃🏼🏄🏼‍♀️📚 she/her

[Jess Orr @Jess0rr]

Delighted to share my first first-author paper from my PhD! Huge thanks to my wonderful colleagues for supporting this work🌟

[Epithelial Cell Biology in ENT Research Group @EpiCENTR_ICH]

Our new paper @AJPLung provides a lentiviral toolkit to monitor airway epithelial cell differentiation using bioluminescence. @Jess0rr developed these during her PhD @lungsforliving... 🧵(1/5)

https://t.co/yyCO8gzTvK

[Epithelial Cell Biology in ENT Research Group @EpiCENTR_ICH]

🚨 New preprint!

With @lungsforliving and @UKRMP_ECE colleagues, we performed phenotypic screening to identify compounds that might promote lung regeneration by inducing primary airway basal cell proliferation.

https://t.co/TtGlDCsJSO

Here's a 🧵 breaking down our findings:

[Epithelial Cell Biology in ENT Research Group @EpiCENTR_ICH]

Our new paper @MolTherapy provides proof-of-concept for a combined cell and gene therapy for airway epidermolysis bullosa (EB).

With colleagues @GreatOrmondSt, we investigated airway disease in EB, a group of rare genetic disorders involving defective cell adhesion 🧵... (1/8)

[Jess Orr @Jess0rr]

Delighted to share this work!
We also created an editable construct if you’d like to track other cell type-specific gene expression in your own cell culture system 👩‍🔬

[Epithelial Cell Biology in ENT Research Group @EpiCENTR_ICH]

🧵 The preprint for our work using lentiviruses to monitor airway epithelial cell differentiation using bioluminescence is now available on @biorxivpreprint! (1/5)

[Marko Nikolić @drmarkonikolic]

Absolutely delighted to share our paper published today in @SciImmunology in collaboration with @teichlab. Huge congratulations to amazing co-first authors @DrJoBarnes, @masahiroy15, @PengHeCam! Team science!

https://t.co/748YBPXk0o

[Jess Orr @Jess0rr]

Important for everyone to listen to this and then to act now 🌍

[DoM_UCL @DoM_UCL]

'A New Climate: Why we need to act, and what we need to do'. Professor Hugh Montgomery
https://t.co/EE20jfxjnm @uclmedsci @domearlycareers @SustainableUCL

[Epithelial Cell Biology in ENT Research Group @EpiCENTR_ICH]

RESEARCH: New work with @paolodecoppi and @Dr_ClaireSmith @UCLchildhealth out @Biomaterials_. We perform decell and recell of rat lungs with human airway basal cells, creating a novel RSV infection model. Introducing human neutrophils to the system is also feasible. 1/2

[Jess Orr @Jess0rr]

@amandatatler @UoNresearch @UoN_BDI Congratulations Amanda!

[VTStemCell2025 @StemVt]

We may be biased, but this takes some beating for the location for a conference dinner! Cruising on the Spirit of Ethan Allen on Lake Champlain. #networking #VTStemcell2023

[Jess Orr @Jess0rr]

Great to present this work at #VTstemcell2023. Thanks to the junior planning committee of @StemVt for selecting my abstract and all involved to create such a fantastic meeting!
@lungsforliving @EpiCENTR_ICH @domearlycareers

[Martijn Nawijn @MC_Nawijn]

Jessica Orb from the ⁦@robhynds⁩ lab presenting her exciting data at the Vermont Stem Cell meeting! ⁦@EarlyCareerERS⁩ ⁦

[Epithelial Cell Biology in ENT Research Group @EpiCENTR_ICH]

With @SwantonLab, we've developed a new python package - PATHOverview - to semi-automatically compile #digitalpathology #NanoZoomer images into publication ready figures: https://t.co/fvm9iFL2Ot

The first output was published today @FrontOncology: https://t.co/A7tGOez5iY

[Jess Orr @Jess0rr]

@JamesParkinSci Congrats James!

[Jess Orr @Jess0rr]

@DrJoBarnes @DoM_UCL Excellent talk Jo!

[Jess Orr @Jess0rr]

Thank you @DoM_UCL for the prize for best PhD poster at the UCL Division of Medicine Retreat!🏅Was great to share the project with the fantastic researchers at #domretreat2023

[DoM_UCL @DoM_UCL]

👏🏼👏🏼Congratulations to @DrPujaMehta1 and @OliviaBracken1 (best PhD and Postdoc oral presentations) and to @Jess0rr and @peppeercoli (best PhD and Postdoc poster presentations) at the #domretreat2023 today!

[Jess Orr @Jess0rr]

@MarineSecchi Thanks Marine!

[Jess Orr @Jess0rr]

Was great to share our work at #LSCN2023 Thanks to the committee, speakers and attendees for such a fantastic conference @LSCN_UK @lungsforliving @EpiCENTR_ICH

[Marine Secchi @MarineSecchi]

First time chairing at #LSCN2023 and I just could not wait to introduce @Jess0rr! Great flash talk and poster Jess!

[Jess Orr @Jess0rr]

@yantracyhu @nih_nhlbi @m_konigshoff @MLSequeiraLopez @BanfieldGomez Congratulations Yan!

[Paolo De Coppi @paolodecoppi]

Great being able to share this work with @Dr_ClaireSmith @soichishibuya @ElvassoreL @robhynds @lungsforliving Fabio Tommasini, Federica Michielin, Alessandro Pelegatta, and many others Lung viral infection modelling in a bioengineered whole-organ https://t.co/nXcbLB6RYH

[Epithelial Cell Biology in ENT Research Group @EpiCENTR_ICH]

PRE-PRINT: @robhynds’s postdoc work on lung cancer patient-derived xenograft models is up @biorxivpreprint. @SwantonLab demonstrate the potential of multi-region PDX derivation to recapitulate intratumour heterogeneity in model systems #PDXmodels