Ji Zhang Lab

[Ji Zhang Lab @JiZhangLab]

It is a great pleasure to share our recent work by Rodney Claude @ScienceGuyRod and Sankalp Srivastava @darwinpwndyou , published at JCI Insight @JCI_insight
https://t.co/6VoeJO7eAL

There are two major findings in this story.

[Ji Zhang Lab @JiZhangLab]

2. Combining L-asparaginase with ASX-173, a newly developed ASNS inhibitor, significantly delays disease progression in ASNS-high ALL models in vivo, without prohibitive toxicity.

[Ji Zhang Lab @JiZhangLab]

1. Despite initial efficacy of GCN2 inhibition in sensitizing acute lymphoblastic leukemia (ALL) cells to L-asparaginase treatment, a subset of Gcn2-deficient cells express ASNS at high levels in a Gcn2-independent manner, which eventually drives therapeutic resistance.

[Ji Zhang Lab @JiZhangLab]

Congratulations to Rodney Claude @ScienceGuyRod . You are officially a doctor now. I am so proud of you. I hope you will enjoy the next stage of your career journey as a PhD.

[Ji Zhang Lab @JiZhangLab]

@schwoerersimon @JuGuillard Congratulations, Simon🎉

[Ji Zhang Lab @JiZhangLab]

@vennetilab @shiva251993 Congratulations 🎉

[Ji Zhang Lab @JiZhangLab]

@PingMu_PhD Well deserved

[Ji Zhang Lab @JiZhangLab]

@schwoerersimon Congratulations

[Herman B Wells Center for Pediatric Research @IUWellsCenter]

Several undergraduate students joined us @IUDeptPeds this summer for 8-week internships with our faculty and research experts, gaining hands-on experience in the world of science and medicine. Read about some of their experiences: https://t.co/Xyodn10SnW

[Herman B Wells Center for Pediatric Research @IUWellsCenter]

With a new $3.2M NHLBI grant to study low oxygen's benefits on blood stem cells, @IUMedSchool @IUDeptPeds scientists aim to expand the reach of advanced stem cell therapies and develop new strategies for treating a range of blood disorders. Read the news: https://t.co/y4Eoqz1CGF

[Ji Zhang Lab @JiZhangLab]

@hongxia_ren @Biomol_MDPI @IUWellsCenter @cevansmo @IUMedSchool @IUSweetTweets @IUStark_Neuro congrats 🎊

[Ji Zhang Lab @JiZhangLab]

@IUWellsCenter @IUDeptPeds @AndreaLConroy @pdackiller It's my great honor to be part of the Wells Center

[Ji Zhang Lab @JiZhangLab]

@rmirmira @CharanyaMurali @NIDDKgov @BreakthroughT1D @HIRN_CC @KovlerDiabetes @ChicagoDRTC @IUSweetTweets Congratulations 🎊

[Ji Zhang Lab @JiZhangLab]

@JiyeonK37151066 @gsducker @Brandon_Faubert @kailong_li_lab @YaleMed @Yale_Urology @YaleCancer @Yale @ChronisLab Congrats 🎊

[Ji Zhang Lab @JiZhangLab]

@TennessenLab Very interesting story. Congratulations 🎊

[Ji Zhang Lab @JiZhangLab]

@HzengPurplelake @ShawnZhu2018 Congrats, it's an interesting story 👏

[Ji Zhang Lab @JiZhangLab]

@HaopengWang_Lab @cell_res Cool story, congratulations 🎊

[Ji Zhang Lab @JiZhangLab]

@statfourwork @MadCapSci @MeyerLab Remind me the nightmare of doing Southern Blot for genotyping🤣

[Ben-Sahra Lab @bensahralab]

The 3rd Midwest Metabolism Meeting is officially announced @LurieCancer! This exciting event is set to take place @NUFeinbergMed in Chicago on Sept 19th. All postdocs and students from the Midwest region are invited to submit their abstracts by March 1st! https://t.co/RjuiXiOKAN