John J. Deneen

ChatGPT Bootstrapping N-A-B-C “Augmented Conversations” and Transformation of Existential Risk Reduction

[John J. Deneen @JohnJDeneen]

@DrPatrick Happy Easter with Nature’s Resilience: https://t.co/Rh9zCjGMfv

After two days of solid wind and torrential rains in Upcountry Ulupalakua, we woke Sunday morning to find that the lemon blossoms on our tree were still intact along with butterflies and birds singing!

[John J. Deneen @JohnJDeneen]

@JMCousteau "Stupidity is knowing the truth, seeing the truth but still believing the lies. And that is more infectious than any other disease."-- Caltech @ProfFeynman

https://t.co/PfOBnXWcmM:

Peace in the Water - Visual Prayer for Whales and Dolphins (4 min.) https://t.co/mqBlM25mYw

[John J. Deneen @JohnJDeneen]

@dejanirasilveir * Jan 23, 2020 - Trump Removes Pollution Protections for America’s Rivers and Streams https://t.co/CxED68maXi

A https://t.co/PfOBnXWcmM: “The current economic paradigm has a very good relationship with a dead nature, and a very bad relationship with living nature.”

[John F Kennedy Jr @John_F_kJr]

🚨 BREAKING NEWS: Dr. Patrick Soon-Shiong Warns Of A Potential “TURBO CANCER” Pandemic — Alarming Questions Raised Over Spike Protein Findings [VIDEO]

🚨 Renowned cancer researcher Dr. Patrick Soon-Shiong sounds the alarm over what he describes as a potential pandemic of aggressive “turbo cancers.” New findings involving spike protein persistence are fueling urgent calls for investigation, transparency, and further scientific research.

🚨 TOP CANCER EXPERT ISSUES SHOCK WARNING: “We Could Be Facing A Pandemic Of Turbo Cancers”

FOLLOW ME, THE NEXT DROP WILL BE SHOCKING.

[Natasha @Natasha_Guess]

Finally, the long-awaited day has arrived!❤️ My husband has just received his first subcutaneous Anktiva injection.

After such a challenging and uncertain time, this moment feels like a true gift and a powerful step forward. We are incredibly grateful to @DrPatrick and the entire ImmunityBio team for their compassion and for making this possible.

My husband may well be the first EU citizen to receive Anktiva off-label, and we feel deeply humbled by that.

We believe Anktiva deserves to reach patients worldwide so many more lives can be saved. In the meantime, my husband has already begun reacting to the first shot. We are monitoring everything closely and will keep you updated with any developments.

We feel so blessed and remain full of hope for a wonderful outcome. Thank you all for your continued prayers and support, they mean more than you know🙏🏻
@ImmunityBio @LoriMills4CA42 @bullishbruk @ChiayuChenMD @richadcock @Av8rLady @CarnivoreKen @CFSCentral @Brandon_r_clark @RobertKennedyJr @US_FDA

[Steve Jurvetson @FutureJurvetson]

Genomics pioneer Craig Venter has passed.

"If you want immortality, do something meaningful with your life."
— J.C. Venter (1946-2026)

So many memories... I served on the board of his Synthetic Genomics for over a decade and invested in four of his companies. He was indefatigable and pitched me on his latest new startup just last month.

He was the first to sequence the human genome — his own; he gave me a hardback book of his Y chromosome sequence, the one with the SRY gene that made him male. He made the first synthetic life form, a living organism with a near-minimal genome fabricated by chemical synthesis. President Obama awarded him the National Medal of Science.

Time and time again, he pushed the bounds of what people thought possible, often engaging the cutting edge of Moore’s Law and the Carlson Curve of plummeting gene sequencing and synthesis costs. He even made a desktop DNA printer.

And he had a keen sense of humor and joie de vivre throughout. Here are some of those moments from 23 years of photoblog posts on him: https://t.co/ydUlKkfBPF

And more in the SynBioBeta Obit: https://t.co/25Rt04C4lb

[John J. Deneen @JohnJDeneen]

* April 5, 2026 - A U.S. clinical trial is investigating neoadjuvant combination immunotherapy for glioblastoma, one of the most challenging and fast progressing cancers. https://t.co/jAe74HhioT

[ImmunityBio, Inc. @ImmunityBio]

Glioblastoma is not only among the most common malignant brain tumors - it is also one of the most aggressive and difficult to treat.

Advancing care requires new approaches.

Learn more about how we are exploring the potential of the immune system to enhance how the body identifies and responds to cancers such as glioblastoma: https://t.co/OhmYvpAzYb

[ImmunityBio, Inc. @ImmunityBio]

Glioblastoma is not only among the most common malignant brain tumors - it is also one of the most aggressive and difficult to treat.

Advancing care requires new approaches.

Learn more about how we are exploring the potential of the immune system to enhance how the body identifies and responds to cancers such as glioblastoma: https://t.co/OhmYvpAzYb

[John J. Deneen @JohnJDeneen]

@DrPatrick Happy Easter, Dr. Pat Soon Shiong https://t.co/rEwgw5LuHA

"Live the full life of the mind, exhilarated by new ideas, intoxicated by the Romance of the unusual." -- Ernest Hemingway

[John J. Deneen @JohnJDeneen]

@DrPatrick Happy Easter with Nature’s Resilience: https://t.co/Rh9zCjGMfv

After two days of solid wind and torrential rains in Upcountry Ulupalakua, we woke Sunday morning to find that the lemon blossoms on our tree were still intact along with butterflies and birds singing!

[Dr. Pat Soon-Shiong @DrPatrick]

This is how we build the 'World Bank of NK Cells' and make Immunotherapy 2.0 accessible to all of humanity. Our M-ceNK Phase 2 clinical trials ongoing with process development from over 60 healthy volunteers and patients with cancer completed to date.

The future of growing natural killer (NK) cells to fight cancer and protect our immune systems is being assembled right now (NANT Leonardo), the first AI machine driven, cell therapy robotic manufacturing system landing soon!

[Dr. Pat Soon-Shiong @DrPatrick]

Here is the exciting world of AI. My presentation of the cancer mind map after a decade of work to prove the hypothesis that empowering the innate and adaptive immune system could cure cancer.

So I dictated some of my talk to an AI platform and became the "source" that is mentioned in this audio... amazingly, it took my mind map and created this conversation! Take a listen, it explains beautifully how we think about attacking cancer.

[John J. Deneen @JohnJDeneen]

@DrPatrick Dive in:
PRESENTATION https://t.co/EVi94HzsCL
PODCAST (20 min.) https://t.co/uVqUrtE0I3

By synthesizing these technologies, we achieve "Healthcare as a Foreign Policy for World Peace."

This is the “Panacea of Peace”—the ultimate realization of the https://t.co/PfOBnXWcmM.

[John J. Deneen @JohnJDeneen]

@DrPatrick Lymphopenia https://t.co/LTMBbPs4cy

[John J. Deneen @JohnJDeneen]

@DrPatrick https://t.co/2IwyYUTg6V, https://t.co/AliXXVK3IF, https://t.co/sfrgzvwvOO, https://t.co/5EXKyrQ6Vw, https://t.co/PfOBnXWcmM, and conversational https://t.co/e7ZfbAnfBA Bioshield - The Panacea of Peace. “Healthcare as a Foreign Policy for World Peace.”

[John J. Deneen @JohnJDeneen]

@FutureJurvetson https://t.co/2IwyYUSIhn Bioshield - The Panacea of Peace. “Healthcare as a Foreign Policy for World Peace." 

*  Feb 9, 2026 - Current & Future Role of Anktiva (N-803): Dr. Soon-Shiong (22 min.) https://t.co/rKQ90HRtKi

* Feb 6, 2026 - Saudi/NVIDIA   https://t.co/K0cA7tRFqO

[John J. Deneen @JohnJDeneen]

@FutureJurvetson THINK DIFFERENT

"...Conformity is the jailer of freedom and the enemy of growth..."
 -- JFK, Aug 1962

Déjà vu -

* Jan 30, 1984 - Steve Jobs intro to the Macintosh at the Boston Computer Society General Meeting (1:2 hrs.)  https://t.co/Yt4dV44Meh

[John J. Deneen @JohnJDeneen]

@FutureJurvetson Resonates with my project: https://t.co/sN8oswXzLZ

[John J. Deneen @JohnJDeneen]

@DrPatrick @ImmunityBio The Bluzone of AI Co-Creating a Regenerative Future Through Systems Thinking & Compassion https://t.co/I8qOQ8lW8y 

🌎 Join the Conversation

MEMEX-Picture Words

Text alone cannot scale with complexity. As complexity rises, visual language becomes mandatory — not optional.

[John J. Deneen @JohnJDeneen]

* Dec 30, 2025 -Tatiana Schlossberg, environmental journalist and JFK’s granddaughter, dies at 35 after terminal cancer diagnosis https://t.co/yFnNZpCdlF

[Dr. Pat Soon-Shiong @DrPatrick]

Merry Christmas to all. Be well, looking forward to 2026.

Your own NK cells supercharged and amplified by Anktiva and stored for life.

[John J. Deneen @JohnJDeneen]

@DrPatrick These findings could guide the development of more effective vaccines and therapies for aging populations.

[John J. Deneen @JohnJDeneen]

@DrPatrick How long does your immune system remember past infections and vaccines?

* Scientists at LLNL’s Center for Accelerator Mass Spectrometry used retrospective radiocarbon birth dating to reveal that memory T cells in the spleen can persist for up to 10 yrs. https://t.co/piBWe7MTqC