@ThePabloMcKay@Xchelcito@Rainmaker1973 I feel like DNA is both data storage and a functional unit though? DNA forms structures and to say it is analogous to metadata, or a โlanguageโ is an oversimplification.
That said, could you describe why you think it canโt store the information to create this (not โforโ this) ?
@ATinyGreenCell I think some ideas in biology can be considered genius?
Many of these arenโt from biologists, but are applied to biology (Physicists, like Francis Crick).
I also think the determination required to reliably publish good data is greater than genius.
(Just my opinion!)
Watching my first Piers Morgan show (podcast?) with @ericweinstein โฆ I feel most scientists should watch it purely for the chat about peer review ๐ โ
@poojaasanwal Tips:
- Outsource all cooking (eating out healthy can be expensive but thats it). Or meal prep all weekday meals on Sunday
- Have enough clothes so you only do washing 1 day a week (preferably same day you are training twice or cooking for the week, for efficient use of time
The platypus is possibly the weirdest animals.
Itโs a mammal but lays eggs, its duck-billed,
beaver-tailed, otter-footed and venomous.
It has electroreceptors for locating prey, eyes with double cones, no stomach, and 10
chromosomes. It's fluorescent and glows under UV light.
Short read phage genome assembly pipeline:
https://t.co/BnBr1JQsFa
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A bit more complicated for short reads... are configuration files really the best way?
Made a simple long read phage assembly pipeline with @AVaitekenas and @samueltmont .
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No logging, no checks, nothing fancy, just click and hope (for now)...
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Need to turn it into a conda package somehow next?
https://t.co/nFeKbv8UMj
I think this is BIG. MutS protein recognizes mismatches in DNA. AlphaFold3, when given the MutS sequence and long DNA with the mismatch, finds the mismatch and models the complex in the correct conformation.
@milja001 Great tool, Iโm just wondering how analyses like these (VIRIDIC included) compare to network based tools like vContact2 ?
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Clustering phage genomes using an โall vs allโ network seems more sensitive to me than average nucleotide identity?
@kirk3gaard@rrwick@GB13Faithless If sequencing is non deterministic and the reads are from a population of bacteria rather than an individual cell (consensus sequence by my understanding), why are most tools for analysis not designed to run on QC reads directly?
Computing limits?
Any feedback appreciated!