Josephine

[Cookie Monster @MeCookieMonster]

Me need a cookie and a nap.

[Crazy Moments @Crazymoments01]

He brought everything he loved to help ❤️

[Anish Moonka @anishmoonka]

In 1935, two American doctors examined seven women's ovaries and saw small lumps. They called them cysts and named the disease after them. They were wrong. It took 91 years to fix.

What we called PCOS is now Polyendocrine Metabolic Ovarian Syndrome (PMOS), announced today in The Lancet by an international panel of doctors and patients. The renaming followed more than a decade of consensus work and 22,000 patient and clinician survey responses.

The lumps Stein and Leventhal saw were never cysts. Modern imaging shows they were follicles, the tiny sacs inside the ovary that grow and release an egg each month, frozen partway through by a hormonal imbalance. PMOS is a multi-system disorder centered in the endocrine system, the body's network of glands that produces hormones like insulin (controls blood sugar), cortisol (the stress hormone), and thyroid hormones (set the body's metabolism). The ovary trouble flows downstream from there.

The naming choice is not academic. When doctors hear "ovary" in a diagnosis, they look at the ovary. "Metabolic" and "endocrine" send them to the whole body.

PMOS affects roughly 1 in 8 women worldwide, more than 170 million people. The WHO estimates 70% have never been diagnosed. Among those who do, 1 in 3 wait more than 2 years, and nearly half see 3 or more doctors first. The CDC reports more than half of women with PMOS develop type 2 diabetes by age 40, a risk 5 to 10 times higher than women without the condition. Around 37% have clinically significant depression, compared with 14% in women without it. Anxiety runs at 42% versus 8.5%.

A label born from a 1935 look at seven ovaries is finally going away. The new diagnostic guidelines roll out fully in 2028. By then, a woman walking into a clinic with these symptoms should hear questions about her blood sugar and her mood alongside her cycle. Those are the parts of the disease the old name hid for 91 years.

[Josephine @Josyjo754]

Common sense is apparently not that common

[Josephine @Josyjo754]

I really love when things work the way they’re supposed to

[Puppies & Positivity @Puppieslover]

“Watch my dog appear out of nowhere when I pour some whipped cream...😂😂”

[Josephine @Josyjo754]

The tinder swindler what the f is this?!

[Today In History @historigins]

That time Adam Sandler and Jennifer Aniston were shocked by the size of an Australian reporter

[Josephine @Josyjo754]

I grew up in Brentwood and my son is growing up asking me to make him fresh pressed green juice 🤣

[Crazy Moments @Crazymoments01]

The sweetest kind of protection 🦌❤️

[Food Network @FoodNetwork]

Rapid fire Q&A with @jacquestorres! 🍫 What do you think of his answers?

Catch Jacques on #SweetEmpire: Winter Wars, Sunday @ 9|8c.

[Food Network @FoodNetwork]

If you love cheese as much as we do, @kardea_brown's Super Decadent Mac and Cheese is for you! 🧀😋

Tune in to Kardea judging #HolidayBakingChampionship TONIGHT at 8|7c!

Get the recipe: https://t.co/r65gOdrmtu.

[Josephine @Josyjo754]

Mama’s outsideeeeeee

[Anne Ortelee @AnneOrtelee]

12:25pm EST: Moon in Scorpio forms a quindecile to Uranus in Taurus and quincunxes Venus in Aries. Part 1 of a Finger of God. Pay attention to subtle differences regarding your health. One change is the seed of the other. And that's encouraging, in the long run.

[Josephine @Josyjo754]

@lifetimetv hi is text me when you get home coming back for another season?

[Fascinating @fasc1nate]

Paranormal investigator Lorraine Warren holds the original Annabelle doll, a "possessed" Raggedy Ann that began terrorizing her owner in 1970.

Allegedly, Annabelle would change positions during the night while her owner slept and start popping up in different rooms throughout the apartment, all on her own.

One day, a friend was taking a nap in the apartment, and, when he woke up, Annabelle was staring at him and he had the feeling he was being strangled before noticing claw marks down his torso.

[Josephine @Josyjo754]

@lifetimetv Is there a new season coming out

[Josephine @Josyjo754]

“He killed 16 Czechoslovakians and was an interior decorator” “really? Because his house looked like shit”

[Anne Ortelee @AnneOrtelee]

5:50pm EDT: Out-of-bounds Moon in Leo square the Nodes of Fate in Scorpio and Taurus. Fateful moments, final countdowns. Are you committed to your dream, for good, for true? 03°Le37' D 03°Ta37' R 03°Sc37' R