Cerebellar dysfunction nearly always causes motor abnormalities - yet the precise presentation of these motor abnormalities varies. Raising the question: what determines the presentation of cerebellar dysfunction?
A thread on our newest preprint:
This was such a Joyful (pun intended) collaboration with @JoyJoyZhou, @luisalazl, @LaurenMiterko, @mpaveskov, @SillitoeLab, and twitter-less Tao, Amanda, Ross, and Dominic.
Did you know that the beta-blocker propranolol is so effective in reducing tremors that it is banned in the Olympics?
But how does it work?
Read it in the new @SillitoeLab paper led by @JoyJoyZhou: https://t.co/ytseXwmRu4
A 🧵
Congratulations @JoyJoyZhou and the @SillitoeLab for this publication investigating how Propranolol modulates cerebellar circuit activity and reduces tremor! 🧠🔬🥼#cerebellum#tremor#circuit
https://t.co/nnQQKvtH5Y
New paper alert:
Influence of data sampling methods on the representation of neural spiking activity in vivo
https://t.co/y9oYQlDjul
@bcmhouston@bcm_neurosci @TCHResearchNews @SillitoeLab
As guest editor, if you have interesting ideas or data about dystonia, especially from the perspective of neurodevelopment, please don't hesitate to click below, or send me a DM!
New paper alert from our @SillitoeLab postdocs, @Meikeesther1 and @jasonsgill, on the links between cerebellar development and ASD! It's a fantastic deep dive into a subject matter that'll only become increasingly relevant bench-to-bedside. https://t.co/3WeUWWBmyk