While I continue to advocate for responsible opioid prescribing, this was the culmination of my 2019 research showing great benefit in our chronic pain subgroup with CBD and the potential for opioid reduction.
@DanLairdMD Agree completely with @DanLairdMD, in fact, from a physicians view, there are inherent disincentives to rx opioids given the amt of time, energy, power, communication with pharmacists and third-party providers that an approval requires, and often needs repeating 6 months later
Everything wrong with medicine is physicians arguing CBD is not safer than Benzos. I really struggle how physicians can be so blinded by “evidence” and not pause to think how one drug can kill you and one can’t. Why do docs overthink things? #commonsense#medtwitter
IMPORTANT: Newsweek Exposes the Truth: Please RT: Doctors Are Taking Away Opioid Prescriptions From A Growing Number of Patients, Report Shows https://t.co/oMaFTjzxxo
@NarouzeMD@ASRA_Society Thank you Dr Narouze for the highlight...I agree with many of the comments (Dr Mikhail had mentioned he would also like to see some functional data) and I totally agree...more work to be done in this promising niche of our pain pharmacology world.
@KNLCBD@NarouzeMD@Peter_Grinspoon@ASRA_Society I think there are many different and very good products, but to say “definitively test opioid reduction” is a tough study to do. OME, length of time on opioids, pharmaco-genetics (both opioid receptor and endocannabinoid receptors) would have to be accounted for to name a few.
@Rxpalli8r @NarouzeMD@painfreeED@ASRA_Society James, this was an initial prospective study where we had better than anticipated results, as such I did not want to change our parameters. Patients were on the entire spectrum of opioids (fentanyl, oxycodone, hydrocodone, methadone, oxymorohone, hydromorphone and others).
@Lambert_Usyd Thank you for highlighting what we feel is a great data on CBD...after the study I had many thoughts...We know that CBD has anti-inflammatory properties, however I feel there are separate nociceptive (pain relieving) mechanisms...TRPV-1 receptor getting looked at.
More data showing #CBD reduced chronic #opioid use.
#Cannabinoid and #pain researchers, are the prevailing theories that CBD is analgesic or that it is potentiating opioids through pharmacokinetic or pharmacodynamic means?
Poster presented at #ASRAFALL19@JulianGroveMD
@PainDocTony Dr Bui, perfect niche and I think you will benefit us all (providers and patients) as there is so much information to disseminate. Well done.
Another day where I put in 45 minutes to try to help an opioid-receiving patient, somewhere in the USA who is being abandoned. Not sure I can come up with individualized letters for all 10 million. It would be awesome to see health systems and regulators take this on with vigor.