Julien Clain

PhD in Microbiology-Immunology from Université Laval, Québec, Canada.
#HIVresearch
From Reunion Island 🇷🇪 974

[Julien Clain @JulienClain_PhD]

Altogether, our findings shed new light on hepatic CD4+ T cell profile that could contribute to liver injury following viral infection.

[Julien Clain @JulienClain_PhD]

I'm proud to share with you my recently published paper in Microbiology Spectrum this September 1st.
Link : https://t.co/8M2RhcJLYi

[Julien Clain @JulienClain_PhD]

Viral infection is associated with the presence of inflamed and activated hepatic CD4+ T cells expressing cytotoxic molecules. Furthermore, hepatic CD4+ T cells are reprogrammed toward lipid metabolism after viral infection.

[Julien Clain @JulienClain_PhD]

In this study, we aimed to assess the contributing role of hepatic CD4+ T cells during HIV infection. Our work demonstrated that hepatic CD4+ T cells express CCR5, the main viral coreceptor, and are infected cells.

[JCI insight @JCI_insight]

Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques: https://t.co/vPp99tgX6V
@chudequebec
#AIDS #HIV

[Julien Clain @JulienClain_PhD]

@Inserm @CRCHUM @UQAM @ViiVHC @GileadSciences @GileadHIV @Merck @universitelaval

[Julien Clain @JulienClain_PhD]

A month ago, one of my thesis works was published in @JCI_insight .
Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques https://t.co/m6sMtRTOqN

Thanks to @EstaquierJ @cancurehiv @CIHR_IRSC @crchuqc @chudequebec and collaborators !

[Julien Clain @JulienClain_PhD]

#HIV #ViralReservoirs #Immunology #CD4 #Macrophages #Liver #Lungs #AntiretroviralTherapy #Research #Science #PhD #Canada #France #INSERMU1124 #Bioinformatics @Inserm @CRCHUM @UQAM @ViiVHC @GileadSciences @GileadHIV @Merck #FRQNT @universitelaval