I'm a cardiologist. I've held dying hearts in my hands in the cath lab at 3 AM. And I need to tell you something that changes everything about how we prevent heart attacks.
For decades, the entire field was built on one target: lower LDL cholesterol. Statins save lives — that's settled science. But too many of my patients did everything right — took their statins, hit their numbers, lived clean — and still ended up on my table with a ruptured artery.
We were treating the smoke while the fire kept burning.
The fire is inflammation. And the evidence is now overwhelming.
The CANTOS trial proved it first — lowering inflammation independent of cholesterol reduced cardiac events. But the newer data is what keeps me up at night.
AI-enhanced CT angiography can now detect inflamed arteries by measuring changes in the fat surrounding your coronary vessels — the perivascular fat attenuation index. Higher inflammation in the fat around even one artery independently predicts cardiac death. When multiple arteries show inflammation, the risk multiplies dramatically — even in patients whose cholesterol looks perfect.
This isn't theoretical. This is measurable. Right now. On a scan you can get this month.
Low-dose colchicine — a drug that's been around for centuries for gout — is now FDA-approved specifically for reducing cardiovascular events. It works by quieting the inflammatory cascade that destabilizes the plaque sitting in your arteries. A pill that costs pennies is saving lives the statins couldn't reach.
And the next wave is already in Phase 3 trials. Ziltivekimab — an IL-6 inhibitor — targets the central inflammatory pathway driving atherosclerosis. Phase 2 data showed a 90% reduction in hsCRP. The ZEUS cardiovascular outcomes trial is enrolling now, with results expected late 2026 into 2027. If positive, anti-inflammatory therapy will become standard in managing heart disease alongside lipid-lowering. The era of inflammation-targeted cardiology is arriving.
But it goes deeper than drugs. AI is now predicting heart failure and cardiac events 5+ years before symptoms — integrating CT imaging, electronic health records, and genetic data with accuracy that jumps far beyond traditional risk calculators.
And polygenic risk scores — a simple genetic test that flags inherited cardiovascular risk — are now formally recognized as a risk-enhancing factor in the 2026 ACC/AHA guidelines. A single blood draw can reveal risk that's been silently building since birth. Decades before the first chest pain.
Here's what this means for you right now — today:
Ask your doctor for a high-sensitivity CRP test. It's cheap, routine, and measures the systemic inflammation that standard cholesterol panels completely miss. You can have perfect LDL and inflamed arteries that are quietly preparing to rupture.
If your hsCRP is elevated, discuss low-dose colchicine with your physician. It's FDA-approved for exactly this.
Push for a coronary CT angiography with AI plaque and inflammation analysis if you have risk factors. This isn't the stress test your parents got. This is 3D visualization of your actual arteries — with AI quantifying not just how much plaque you have, but what kind it is and whether the surrounding tissue is inflamed.
Consider polygenic risk score testing — especially with a family history of early heart disease. It's now guideline-supported.
And the foundation that never changes: move daily, eat real food, sleep 7-9 hours, manage stress, and know your numbers — ApoB, Lp(a), hsCRP, fasting insulin.
I left Iran as a child with nothing. I rebuilt everything in a country that gave me the freedom to become a physician. I've spent twenty years watching patients get second chances.
The ones who haunt me aren't the ones who died on my table. They're the ones who survived but never acted on what the science was telling them — years before the event that didn't have to happen.
You can have perfect cholesterol and still have a heart attack. Inflammation plus genetics can drive plaque rupture in arteries that look "fine" on a standard panel.
The myth that normal cholesterol means you're safe has cost more lives than I can count.
We now have the tools to detect the fire — not just the smoke. AI to see it. Genetics to predict it. Drugs to quiet it. And the ancient basics — movement, real food, sleep, purpose — to prevent it from starting.
Prevention is the new cure. And the science to make it real is no longer coming.
It's here.
As a filmmaker, I believe cinema should entertain, inspire, and connect with audiences. It should never make anyone feel uncomfortable or disrespected. We have heard the feedback regarding certain scenes in Peddi and have taken it seriously.
I have always had immense respect for women, both on and off screen, and it was never our intention to objectify or disrespect any female character. If any part of the film has been perceived that way, we respect those sentiments, understand the concerns being raised, and sincerely apologize.
After reviewing the feedback, we have decided to make changes to the concerned portions. Cinema grows through its connection with audiences, and as storytellers, we have a responsibility to be mindful of evolving perspectives and sensitivities.
Every woman deserves to be respected, valued, and represented with dignity. We remain committed to telling stories that celebrate strong characters and uphold those values.
Thank you to everyone who shared their views honestly and sincerely."
‼️Trigger Warning‼️
Absolutely heartbreaking!
A grievously injured worker from the horrific accident at RINL Steel Plant, Vishaakhapatnam got his last words recorded.
He asked his elder son to take care of his younger brother, and both of them to study well. He also asked him to take care of their mother. Saying these words, he closed his eyes. He had asked his colleague to record his goodbye video!
The ladle with molten steel exploded at 25 feet height and causing a terrible fire accident at Vizag Steel Plant yesterday. The ultra-high temperature of nearly 1,600 degrees celsius at the operation site has made the situation even worse.
The condition of those who survived is not looking great with most suffering from 40 to 90 percent third degree burns. The number of casualties are escalating.
Many heartbreaking stories like this are emerging.
The official reason is yet to be determined but as per the employees, it is a maintenance issue.
Prime Minister Narendra Modi announced ex-gratia of Rs 2 lakh from the PM National Relief Fund to the family of each of the deceased, and Rs 50,000 to the injured.
The union steel ministry announced Rs 25 lakh ex-gratia to the family of the deceased and Rs 10 lakh to the injured.
No amount of ex-gratia can make the family recover from this loss. I hope they find strength to deal with this 🙏🏽
Situation is very grim in #PoJK but the Indian media is not even bothering to cover it. During 370, Pakistan had ensured India became an international villain when we did nothing to the civilians. Now compare with this..!
@ManjariFadnis Maaam....think about the mother's who lost their sons due to Rabies!...no street dogs...only pet 🐶 and that to owners should shelter them in yheir homes.!
@drunkJournalist If your religion was actually the best religeon wouldn't cry 4r bans & police raids on 'illegal conversions'. You'd welcome the challenge like bring it on...! 😁😆. Can u stop the light with hands ✋️ 😆. So dont worry bruh! Challenge it, dont change ur tone it doesn't suits u
This is the level of Brainwash Maulans Do To Convert Hindu.
Look at Aayush Malik now Mohammad Ali.
Altough he didn't changed his Hindu name.
He is saying:
"Maulvi told me how to wash hands..
Then I saw this is How Doctor wash their hands."
Insane level of Brainwashing..
A young woman:
🗣️ “I also followed Cockroach Janata Party because I thought they were raising genuine issues🪳
But later I then saw links to AAP & it's just propaganda.
Youth also understands what BJP has done for the country."
Two Indian Muslim brothers working in Saudi Arabia donated money to Iran to show Ummah solidarity. Now Saudi Arabia has sent them to jail and family wants Indian govt to intervene. Please don’t @MEAIndia
India is for Indians only, not Ummah lovers 🤡🤡🤡
Police stopped them because they were not wearing helmet and these two idiots argued with the police, even pushed the cops and abused them.
If something like this had happened in US, police would have thrown them on the ground, tased them and handcuffed them.
People in India feel they can get away with anything and that's why they don't follow the rules.
Just put bodycams on the cops and give them tasers, a lot of things will get solved.
Meanwhile Muslims of India 🤡🤡
Nashik TCS Case: Nida Khan’s Confession
In the Nashik TCS case, the main accused, Nida Khan, admitted that she had invited the victim to her home and taught her how to offer namaz (Islamic prayers). The investigation revealed that the accused—Danish, Nida, and Tauseef Attar—allegedly planned the religious conversion at a café on the seventh floor of their office building.
A forensic examination of the victim’s mobile phone reportedly recovered 37 audio clips and four religion-related applications. It is also alleged that the victim was pressured to observe fasting during Ramadan.
The police are currently investigating the “Ajmer angle” of the case and examining the accused’s contacts with a maulvi (Islamic cleric)
What a c@ncer cult
KERALA : Clerics body slams IUML's first woman MLA Fathima Thahiliya for lighting ceremonial lamp at a event.
But guess who is communal in this country.
KERALA : Clerics body slams IUML's first woman MLA Fathima Thahiliya for lighting ceremonial lamp at a event.
But guess who is communal in this country.
Lebanon was the only Christian-majority nation in the Middle East.
It's where I was born.
We prided ourselves on inclusivity. Always welcoming Arab Muslim refugees from all over the Middle East.
We had the best economy despite having no natural oil. The best universities.
They called Beirut the "Paris of the Middle East" and the Mountains of Lebanon was a tourist destination.
My early childhood was idyllic, my father was a prosperous businessman in town and my mother was at home with me, an only child.
Slowly, the Arab Muslims began to become the majority in Lebanon and our rights began to wither away.
Soon, we would find ourselves unable to leave our small Christian town without fear of being stopped and killed by Arabs. In Lebanon your religion is on your government issued ID.
As the war intensified and the radical Islamists made their way south, my home was hit by an errant rocket and my life was forever changed.
We spent the next almost decade in a bomb shelter, scraping together pennies and eating dandelions and roots just to survive.
If it was not for Israel coming in and surrounding our town, I do not know If I would be here today.
Lebanon is now a country 100% controlled and run by Hezbollah. I lost my country of birth.
I thank God every single day I was able to immigrate to America and live out the dream that BILLIONS of people only dream of having.
Now here in America, my adopted country that I have come to love so much, I see the same threats and warning signs happening now that took place in Lebanon when I was a child.
This is my warning to you, America, reverse course now while you still can.
It's not too late to save our freedom and preserve it for the next generation.
@VijayWithINDIA@AjayJadeja171@Hindustan_King1 So why its okay if others declare we r an izlamic yet they have freedom f9r not to say that yet they did..but problem arises...if the same logic argument is brought up by others..