Kate Miyasaki

MSc candidate in the Mukherjee Lab, McMaster University

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
EVIDENCE: “High-Contrast In Vivo Imaging of Tau Pathologies in Alzheimer’s...”
https://t.co/64SZGPYoAm
Novel imaging probe used with PET scans detects tau deposits in murine tauopathy models and patients with Alzheimer’s Disease

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
NEWS: “Brain imaging of tau protein in patients with various forms of dementia”
https://t.co/NI28RQvKeH

[Kate Miyasaki @KateMiyasaki]

Thank you @DrMMukherjee for being an amazing supervisor!

[Manali Mukherjee @DrMMukherjee]

Super proud of @KateMiyasaki, a fourth-year undergraduate @MacHealthSci to have won the CSACI oral presentation 2020 for presenting her research work over this summer investigating the effects of autoantibodies on macrophages in severe asthma #woot #Mukherjeelab @CSACI_ca

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
EVIDENCE: “An Immunomodulatory Therapeutic Vaccine Targeting Oligomeric Amyloid-B”
DOI: 10.3233/JAD-200413
E22W42 DC-vaccine increases antibodies against toxic oligomeric amyloid-B to slow memory impairment in Alzheimer’s mouse models

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
NEWS: “New vaccine could help halt Alzheimer’s progression, preclinical study finds”
https://t.co/VFicLmcU07

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
EVIDENCE: “A new neutrophil subset promotes CNS neuron survival and axon regeneration”
https://t.co/ZpI0H31f34

New neutrophilic-like cell secretes growth factors to induce axon regeneration and optic nerve and spinal cord repair.

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
NEWS: “Discovery of New Immune Cell Type May Unlock Strategies against Neurological Disorders and CNS Damage”
https://t.co/Bk0tf3buvo

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
EVIDENCE: “Highly pathogenic H5N1...”
https://t.co/l9krd3exYN
H5N1 avian virus enters the CNS, activates microglia and causes alpha synuclein protein aggregation that leads to the loss of SNpc dopaminergic neurons

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
NEWS: “Can the Flu and Other Viruses Cause Neurodegeneration”
https://t.co/DGoT8c8Jec

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
EVIDENCE: "Long-Term Neuroinflammation..."
https://t.co/BA3L1IUCas
Infection with H7N7 and H3N2 cause spine loss in mice
H7N7 and H3N2 have inflammatory and glia specific genes correlating to increased microglial activation and hippocampal alterations

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
NEWS: “Flu May Impact Brain Health”
https://t.co/LHC8CHvxv7.

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
EVIDENCE: "Neuroinvasion of SARS-CoV-2 in human and mouse brain"
Note that this is a preprint that has yet to be peer reviewed
https://t.co/PzzYxUSQ96
Key findings:
- SARS-CoV-2 invades/infects cortical neurons by the use of ACE2 receptors

[Kate Miyasaki @KateMiyasaki]

@hthsci4bb3 #4bb3neuroimmune
NEWS: "How the Coronavirus Attacks the Brain" https://t.co/HFHq1RC1CB.