We are thrilled to share our work demonstrating that electronically diverse and medicinally relevant heteroaryl groups can be used as handles for systematically tuning thiol reactivity of covalent reactive groups. @pitt_Chemistry https://t.co/Qgl9XJWf0i
Aaron Balog @bmsnews disclosing molecular glue degrader of Helios & Eos BMS-986449 at #AACR25@AACR. Fine-tuning of the IMiD core including positioning a chiral methyl group enabled selective degradation leading to a potent modulator of Treg activity now in clinical trials.
Excited to introduce our website and preprint about HArD, a database of heteroaryl descriptors. If you ever wondered "what is the Hammett constant for 2-pyridyl?" or any other heteroaryl group, now you can do a simple search at: https://t.co/eOQzyiVfOm
https://t.co/hbjunbajjn
Congrats to the Horne group for their recent work on mimicking the structure of antimicrobial Plectisin through artificial changes to protein backbone connectivity in Chem Biochem. Read more: https://t.co/m8PNyRzZmu
Please join us in congratulating Prof. Peng Liu on being named the Richard King Mellon Chair of Chemistry - a well-deserved honor recognizing Peng’s achievements in research, teaching, and mentorship! https://t.co/tz7uYpqf0o
📢 Missed one of the latest #BeilsteinTalks?
Check out the #BeilsteinTalks series in the 🎥 video portal @TIB_AVPortal @TIBHannover 🔗 https://t.co/CE2lHmSERs
More talks to start soon in January 2025! ➡️ https://t.co/t5oVEEjOgw
@DrGlycoBen @Trujillo_Group @KayBrummond
Good news–my favorite collaborator has just graduated from Pitt. Bad news–my favorite collaborator has just graduated. Congratulations Luke! I wish you much continued success! @pengliu_group@Pitt_Chemistry
Super excited to share our work on the Stereo-Differentiating Asymmetric Rh(I)-Catalyzed Pauson–Khand Reaction: A DFT-Informed Approach to Thapsigargin Stereoisomers | Journal of the American Chemical Society https://t.co/zFGeLGG62a