Dita De Boni

Journalist , columnist, writer.

[Basem Alhabel @BAlhabel]

Amid exhaustion and hunger, a child in Gaza holds his injured brother, trying to wake him to feed him a piece of wafer he saved for him... a scene that captures the innocence of children amid the harshness of life and sleeping on the streets.

[Mahmoud Massri | مَحْمُود 🇵🇸 @MahmoudMassri15]

Samah went to the dentist to treat her teeth, but during the anesthesia injection, a terrible accident happened — the needle broke inside her molar and gum.

Now, the swelling in her mouth and face is getting worse over time, and she is suffering from severe pain and a serious health risk. She urgently needs surgery to remove the broken needle from her molar, as shown in the image.

The emergency surgery costs only $200, but in these extremely difficult circumstances, this amount is very hard for us to afford.

I beg you from the bottom of my heart to please help Samah, whether by donating or simply sharing her story with others. Your support or even your share could be the reason she gets relief from this pain and danger. 🙏💔

[Dita De Boni @KeepingMum]

@academic_la You are doing something great

[Parwiz Hamidi _🇵🇸 @Palestine001_]

Never stop talking about Palestine!

[B.M. @ireallyhateyou]

C'mon, people, today we're boosting Karim's campaign! He has no one but us!
https://t.co/7fdXlWb5eI

[NCCM @nccm]

We are horrified by yet another incident of violent Islamophobia that occurred last Friday in St. Albert, Alberta. A Muslim man and his wife were driving back home from the Muslim Association of St. Albert when he was allegedly brutally assaulted.

The man was allegedly slammed to the ground, and was accosted with racial obscenities, the attacker called him a "f***king immigrant," insulted Islam, used the n-word and threatened to kill him. He suffered a laceration to his right eye and pavement burns. 

Violent Islamophobia has continued to be on the rise, and so has the rise of hatred directed towards immigrants across the province of Alberta. 

We cannot stand by and have instances like this occur on a regular basis, all levels of government must condemn this incident and commit to taking action, as well as changing the current racist discourse around immigration. 

We will be in contact with the victim and local authorities.

[B.M. @ireallyhateyou]

Don't let the nightmare become a reality. Stand with this sick mother in Gaza and her terrified daughter. Help them in any way you can. Follow, donate, and share. Please.

[Gaza Notifications @gazanotice]

🚨HEARTBREAKING : Critically Injured Child After Israeli Airstrike in Gaza

2 year old Salem Al-Najjar is fighting for his life after an Israeli strike hit near his home, causing him to fall from the third floor. He suffered severe brain hemorrhage, organ damage, and is now on life support with declining consciousness.

Doctors warn his condition is critical and could worsen at any moment. He urgently needs medical evacuation abroad to survive before it’s too late.

[Karim @toot3577088]

Can you please help me

[Lobna Nashwan🇵🇸om jameel @lobnamkm1987]

I am lobna, a Palestinian citizen,& I write this message with sadness. The war has shattered my dreams. My family is struggling to eat, We are suffering from malnutrition, and no one cares.
Give us a glimmer of hope to survive: 😔⬇️🍉"
@ainiladra
https://t.co/yYJQcwy6vl

[𝓙𝓲𝓶𝓶𝔂 𝓙 @JimmyJ4thewin]

On World Press Freedom Day, many are paying tribute to the journalists kiIIed by lsraeI.

[edward miller @labourcartel]

If India thinks NZ hasn't done enough to promote $34bn FDI into India in 15 years, India can "undertake proportionate remedial measures to rebalance the concessions provided to New Zealand".

https://t.co/IB5piE9S6b

[Kegham Balian @kbalian90]

BREAKING: Israeli Police have released footage of the French nun who was violently assaulted by a 36-year-old Jewish extremist in front of the cenacle on Mount Zion.

[M a h a 𓂆 @Mahayasir248909]

All I can say… is that we are suffocating from the intensity of suffering in Gaza 💔

The situation has become unbearable…
we are just trying to hold on.

If you can, please don’t hesitate to donate or share, my friends 🙏
https://t.co/d5QYFQ9mRb

[John Hudson @John_Hudson]

can't believe that just happened: Trump got a NASA question and deferred to NASA administrator Jared Isaacman, saying "the best man to tell you that is the man sitting right over here. You heard that question with those beautiful ears of yours ... He's got super hearing"

[Dita De Boni @KeepingMum]

@secondzeit You are a cracker magnet

[Eye on Palestine @EyeonPalestine]

Hussam Yousef Hussam Abu Hayyah (7 years old) has suffered from continuous seizures and speech and mobility delays since birth. His condition has recently worsened, as he now endures severe and frequent daily epileptic seizures that prevent him from sleeping,

[Aakash Gupta @aakashgupta]

Spouses of Alzheimer's patients are 6 times more likely to develop Alzheimer's themselves. They share daily saliva exchange for decades. Their oral bacteria converges to the same strains.

In 2019 Cortexyme published a paper in Science Advances showing Porphyromonas gingivalis, the bacterium behind gum disease, was present in over 90% of postmortem Alzheimer's brains. They also found its DNA in the cerebrospinal fluid of living Alzheimer's patients.

P. gingivalis is the keystone pathogen of periodontitis. The CDC says 47% of American adults over 30 have periodontitis right now.

The mechanism is specific. P. gingivalis produces enzymes called gingipains. Two types: one cuts proteins at lysine residues, the other at arginine. Tau, the protein that holds your neuronal scaffolding together, is loaded with both amino acids. In cell culture, gingipains shred soluble tau within one hour of infection. The fragments seed the paired helical filaments that become tangles. Tangles are Alzheimer's.

Mice fed P. gingivalis through the mouth grew amyloid plaques in their brains. Hippocampal neurons died. The bacteria crossed the blood-brain barrier and started chewing through the same proteins that fail in human Alzheimer's patients.

Cortexyme built a drug called atuzaginstat to block gingipains. Phase 1 was clean. They ran a 643-patient Phase 2/3 trial called GAIN.

The FDA hit it with a partial clinical hold for liver toxicity. The drug missed both primary endpoints. In August 2022 Cortexyme shut the program down, renamed itself Quince, and pivoted to bone disease.

The subgroup with the highest baseline P. gingivalis loads still showed cognitive improvement on secondary endpoints. The bacteria itself kept showing up in postmortem brains across independent studies after the trial closed.

Periodontal disease shows up 10 to 20 years before cognitive symptoms in people who later develop Alzheimer's. By the time someone forgets a name, the bacteria has been working for two decades.

The intervention point is upstream of your skull.

[Brent Terhune in Cincinnatti July 11 @BrentTerhune]

Correspondents’ Dinner Eyewitness

[Max Blumenthal @MaxBlumenthal]

Lockheed Martin CEO Jim Taiclet tells investors the US-Israeli war on Iran and assaults across the region are a "golden opportunity"

Lockheed tested its new Precision Strike Missile on a girl's volleyball game in Lamerd, Iran on Feb 28, killing and wounding dozens