BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
First ever engraftment and maturation of autologous iPSC-cardios post-infarct without immunosuppression (out to 14 months). Incredible bicoastal collab with Cindy Dunbar & Manfred Boehm’s team @nih_nhlbi to pull this off—what a journey!
@UWISCRM@UWMedicine
Epicardial Gene Therapy for Refractory Angina. The EXACT Phase 2 Trial. Improved Symptoms, Exercise Tolerance and Ischemia at 12months with VEGF Gene Therapy. A simultaneous publication with #SCAI2024@SCAI@faisalbakaeen#cardiotwitter#AHAJournals https://t.co/EEvDQp1jwa
How it started vs how it’s going
One of the major roadblocks for #heartreneration is the onset of arrhythmias after hPSC-CMs #celltherapy.
We were finally able to overcome this adverse reaction with the #MEDUSA project, published this week on @CellStemCell; so proud of our team!
🎉 Our #GWAS of gestational diabetes in #FinnGen is now available on medrxiv! We disentangle the genetic relationship of GDM with Type 2 diabetes using new methods we think could be much more broadly useful.
A brief thread 🧵 1/7
https://t.co/VEJISlCyXX
Congrats to @chrisryanburke and surgical team for first cardiac gene therapy at @UWMedicine. Many thanks to @UWMedHeart Clinical Trials Unit @KateKearney4@DrBillLombardi and sponsor XyloCor for this milestone towards novel regenerative therapies for our patients.
@KentaMD introduces a new clinical trial with human vascular endothelial growth factor (VEGF) to induce therapeutic angiogenesis.
@UWMedicine is one of two trial sites on the west coast.
More info available @ https://t.co/HUitdaFMKR
#MedTwitter#clinicaltrials@uwmnewsroom
Proud of our team tackling the challenges ahead for genuine cardiac remuscularization. Thank you Lauren Neidig @SilviaMarchia@berteroale@MRobinsonEP, Chuck Murry and Robb MacLellan and @UWMedicine for one step of many towards offering this strategy to our patients.
The new issue is now online. Read the latest research including the cover report on pharmacologic therapy for engraftment arrhythmia induced by transplantation of human cardiomyocytes https://t.co/YQchufX1zw. @UWISCRM@UWMedicine@uwmnewsroom@martinperaJAX@ISSCR