Since I reversed my type 2 diabetes 11 years ago with the #ketogenic diet, I am the #KetoActivist - let's spread the word for the astonishing health benefits!
Now at @keto_live Prof Longhitano discussing The idea that “Keto is the mTOR switch” referring to the ketogenic (keto) diet’s ability to downregulate or “turn off” the mTOR (mechanistic target of rapamycin) pathway, mimicking some effects of fasting, calorie restriction, or drugs like rapamycin.
What is mTOR?
mTOR is a key protein complex (mainly mTORC1) that acts as a nutrient and energy sensor in cells. It promotes:
• Cell growth, proliferation, and protein synthesis (anabolic processes).
• When nutrients (especially carbs, amino acids like leucine, and insulin signals) are abundant, mTOR is activated (“switched on”) to support growth, muscle building, and reproduction.
• Chronic overactivation is linked to aging, cancer, metabolic issues, inflammation, and certain epilepsies.
In contrast, inhibiting mTOR shifts the body toward repair, autophagy (cellular cleanup), fat metabolism, and longevity pathways.
Meet Dr David Unwin @lowcarbGP Live in🇨🇭to learn and discuss the latest science news on NCDs and Metabolic Health at the CME- certified 6th international Keto Live Conference from June 8th - 12th
https://t.co/IsLma5ZpZB via @YouTube
Several of my colleagues, including Dr. Tomas Duraj, will present at The Keto Live Conference in Switzerland from June 8-12. You can learn about the event on their website: https://t.co/RBF4sg4ViO @drtomasduraj@keto_live
I was a blank slate on this topic prior to recording this podcast. Luckily I had the great Tony Stella guiding me through the Golden Age of the Ninja with special emphasis on one of his favorites - 'Castle of Owls' (1963): https://t.co/4SXGTCh29S
RIP Tony Stella. The world has lost a true artist. Tony was one of the last bastions of hand-painted movie poster art. He created this amazing FULL METAL JACKET piece shortly before he died. He only shared it with me and a few others. I hope someone puts out a coffee table book of his work someday. 🙏
What if the most popular metabolic diet actually hides a molecular secret to fighting osteoporosis?
Osteoporosis remains a critical global health challenge. While ketogenic diets are praised for managing obesity and diabetes, their impact on bone microarchitecture has sparked intense debate.
🔬 The discovery: A new comprehensive Open Access review reveals a fascinating paradox in bone metabolism.
💡 The conflict: The classic ketogenic diet appears to inhibit bone accumulation and damage bone tissue structure over time.
🧬 The plot twist: However, β-hydroxybutyrate (BHB), the primary ketone body produced during ketosis, actually ameliorates osteoporosis by promoting bone-building cells and blocking bone-destroying ones.
📈 The impact: This divergence between the whole diet and its key metabolite opens up incredible therapeutic possibilities.
🌍 The future: Next-generation treatments could harness BHB directly to treat bone loss, offering the skeletal benefits of ketosis without the dietary risks.
Congratulations to Changfang Luo, Zhuojun Dai, Yong Xu, Wei Huang, and the entire team for this crucial work.
Read the full review published in Frontiers in Nutrition (Frontiers): https://t.co/2BxaywWsdp
📚 Discover more papers published in Frontiers in Nutrition (Frontiers) in the Research Topic on "Ketogenic Metabolic Therapies - Volume 1", an initiative from the European Keto Live Center: https://t.co/oYJOVy6dEb
Want to dive deeper into the science of ketosis and metabolic therapies?
Join the discussion at the 6th International Keto Live Conference from June 8th to 12th at the Hotel Reine Victoria in St. Moritz, Switzerland. 🗓️ Learn more here: https://t.co/tK7eY0tGni
hashtag#Osteoporosis hashtag#KetogenicDiet hashtag#Metabolism hashtag#BoneHealth hashtag#MolecularBiology
❓ What if we could literally rewind the biological clock and reverse the accelerated aging caused by obesity?
💡 Obesity is widely recognized as a primary risk factor for chronic diseases, largely because it triggers early biological aging at the cellular level. This premature aging alters our DNA over time and severely accelerates metabolic decline.
🔬 A groundbreaking new study utilized epigenetic clocks, advanced tools that track DNA methylation to estimate true biological age, evaluating patients with obesity on a Very Low-Calorie Ketogenic Diet. Researchers discovered that adherence to this protocol significantly slowed down the accelerated aging caused by obesity. This powerful effect was directly linked to nutritional ketosis and improved metabolic health, rather than just body weight loss alone.
📈 This opens an entirely new perspective on therapeutic nutrition, demonstrating that targeted dietary interventions can actively reverse molecular aging. By leveraging nutritional ketosis, we have a clear pathway to improve long-term metabolic health and potentially extend human life expectancy.
🧬 Congratulations to the brilliant team behind this Open Access paper, including Andrea G Izquierdo, Ph.D., Paula Lorenzo, Ángel Díaz-Lagares, and Ana B Crujeiras. Your research published in Nutrients MDPI is an incredible leap forward for precision medicine!
📌 Read the full open access publication here: https://t.co/XjBlq236pJ
🗣️ Want to dive deeper into the latest breakthroughs in metabolic therapy? Join the discussion at the 6th International Keto Live Conference from June 8th to 12th at the Hotel Reine Victoria in St. Moritz, Switzerland.
🗓️ Learn more here: https://t.co/tK7eY0tGni
#Epigenetics #Ketosis #BiologicalAging #PrecisionMedicine #MetabolicHealth
Pleased to announce that we are presenting @realDaveFeldman’s #ColesterolCodeMovie at the 6th International Keto Live Conference on June 10th! More information at
https://t.co/Pl65Xr3AM7
Here is the form (please lmk if there are any issues)! I'll try to get to as many of y'all as I can: https://t.co/3j5bix5ZQn ---- 🔥 Overview of metabolic therapies:
Meet our Metabolic Neurology, Psychiatry & Psychology Experts in St. Moritz🇨🇭Switzerland! Join us, register at https://t.co/AEgLv9J1PC to learn and discuss live with: Dr Iain Campbell @IainCampbellPhD @EdinburghUni, Dr Ana Iacob Hôpital du Valais @hopitalvs, Assoc Prof. Dr Carlo Longhitano @doncaloger0 @JamesCookUniversity, Assoc Prof. Dr Kirk Nylen @KirkNylen @UniversityofToronto, @drjenunwin, @DrNathanBryan, Assoc Prof. Dr Martha Spilioti #AristotleUniversityofThessaloniki, Assoc Prof. Dr Christos Chinopoulos #SemmelweisUniversity, and Prof. Dr @GuidoFrank #UCSanDiego
The Conference language is English, with simultaneous AI translation into German, French, Italian, Dutch, and more languages if requested. Accommodation and the delicious #KetoFullBoard have to be booked separately by contacting the Hotel Reine Victoria directly at +41 81 553 90 00 or via Email at [email protected] #Wecantwait to see you there!
One last beautiful push towards recruitment for my study. Eligibility criteria are as follows:
Adults (18 years and older) or adolescents (ages 14-17) with signed parental consent.
Must be using or have used a ketogenic diet as part of treatment for mental illness.
Must have prior baseline and follow-up scores showing at least a 50% improvement on mood assessment (such as PHQ-9, GAD-7, DASS, PCL-5, or other validated instruments relevant to prior or existing diagnosis).
Stable in the use of the ketogenic diet and not currently receiving regular consultation from a dietary professional.
Self-reported confirmation of ketone levels at some point during the ketogenic diet treatment (through blood, breath, or urine).
Currently, self-identify as recovered or in the process of recovering from a mental illness categorized under DSM-V.
Must be physically present in the United States at the time of participation.
https://t.co/fjZFPIg4LG
Please share!
Join me in Middletown, NY for the premiere screening of The Cholesterol Code.
After the film, I’ll be joined for a live discussion with Dr. Alan Schaffer, Nina Teicholz, and Coach Amy Eiges as we explore the science of cholesterol, metabolic health, and the growing debate around diet, lipids, and cardiovascular risk.
Location: AMC Crystal Run 16, Middletown, NY
We need to reserve tickets in ADVNACE to make this showing possible so please sign up here:
https://t.co/vDN9K5PPjy
We are proud to peer-review and publish these impressive results at our Research Topic "Ketogenic Metabolic Therapies in Prevention and Treatment of NCDs" https://t.co/twfwrJgj5b
Volume II is still open for submission till March 31st