Ever wonder how the pianist can perform a new piece from sheet music, or effortlessly play a well-practiced sonata in a concert? We study the underlying neural circuits in ‘piano-playing’ rats and show that motor cortex and basal ganglia play different roles.
This was a fun project that spanned my entire time in grad school. Very grateful for the guidance of @BOlveczky, collaborators extraordinaire @Jack_W_Lindsey@seanescola, and the rest of the Ölveczky lab. Now on to the postdoc!
Ever wonder how the pianist can perform a new piece from sheet music, or effortlessly play a well-practiced sonata in a concert? We study the underlying neural circuits in ‘piano-playing’ rats and show that motor cortex and basal ganglia play different roles.
Remarkably, this architecture and learning rule naturally gives rise to the interference effect described above, where simultaneously learning flexible and automatic sequences prevents the consolidation of the automatic behavior.