Aravind SN

Doctor.
Just here to save tweets for my reference as retweets and rant 🤪.
He / அவன்

[Aravind SN @Kidd12Minion]

Gonna post all my daily wordles here under this tweet 🤌

[Aravind SN @Kidd12Minion]

@SaravanakumarOG Terminal 2 nu oru restaurant Iruku sir , 24x7 open :)

[Aravind SN @Kidd12Minion]

@SaravanakumarOG @Subatheesh_12 "வாடினேன் வாடி வருந்தினேன் ... பெருந்துயர் இடும்பையில்"

OG pathi thaan Thirumangai Azhwar apove solirukaaru pola sir 🥹🙏🏼.

[Aravind SN @Kidd12Minion]

@curious_mk7 Thank you 🙏🏼

[Aravind SN @Kidd12Minion]

With Perumal’s grace got 1.7k in NEETPG26🙏❤️.

MD/DNB Medicine Dilemma
MD in TN - Might get Madurai / Thanjavur if lucky , will get Coimbatore/ Omandurar / ESIC.
DNB - Hindu Rao / St Stephens / GMSH Sector 16 / KMCH / GKNM .

Any ideas and opinion about MD vs DNB welcome 🙏.

[Aravind SN @Kidd12Minion]

@SaravanakumarOG Thank you sir 😊

[Aravind SN @Kidd12Minion]

#medtwitter #neetpg #neetpg2026 #neetpgcounselling

[Aravind SN @Kidd12Minion]

With Perumal’s grace got 1.7k in NEETPG26🙏❤️.

MD/DNB Medicine Dilemma
MD in TN - Might get Madurai / Thanjavur if lucky , will get Coimbatore/ Omandurar / ESIC.
DNB - Hindu Rao / St Stephens / GMSH Sector 16 / KMCH / GKNM .

Any ideas and opinion about MD vs DNB welcome 🙏.

[Aravind SN @Kidd12Minion]

@DocInDilemma @Sickindian1 @Subatheesh_12 They post in rural PHCs that is a minus only . Even after MD/MS.

[Aravind SN @Kidd12Minion]

#neetpg #neetpg2026 #neetpgcounselling #mdvsdnb

[Aravind SN @Kidd12Minion]

Hope it becomes true 🙏. Very much tired of seeing today and soon for the past 15 days.

[Anuja Jaisswal @AnujaJaiswalTOI]

#BREAKING | NEET-PG 2026 result to be declared today
Thousands of #medical aspirants await the result, which will determine their admission prospects for postgraduate medical courses. @timesofindia @NBEMS_Official @MoHFW_INDIA

#NEETPG2026 #NEETPG #NEETPGResult

[Dr.Mukesh , MD , DM @dr_immuno29]

DISTAL WEAKNESS IN DERMATOMYOSITIS — look beyond the usual proximal pattern

IIM classically presents with proximal muscle weakness.

But what if a patient has:

• Typical DM cutaneous manifestations
• Established proximal weakness
• Significant distal weakness
• Contractures

This is not automatically IBM.

Think of an anti-NXP2 dermatomyositis phenotype, particularly when distal weakness accompanies contractures, calcinosis, edema, muscle atrophy or dysphagia.

Why NXP2?

Anti-NXP2 DM can have more extensive muscle involvement than conventional DM.

Reported adult associations include:
• Distal arm weakness ~35%
• Distal leg weakness ~25%
• Dysphagia ~62%
• Subcutaneous edema ~36%
• Calcinosis ~30%

Contractures are an especially important clue in juvenile/young-onset disease, where severe myositis, muscle atrophy and calcinosis may coexist.

A practical approach

DM rash + proximal AND distal weakness + contractures

→ Define the exact weakness pattern
→ Look for calcinosis, edema, atrophy, neck weakness and dysphagia
→ CK/aldolase/LDH + MSA/MAA, including anti-NXP2
→ MRI: assess proximal + relevant distal compartments
→ EMG/NCS if neuropathy is a competing possibility
→ Targeted biopsy when phenotype and serology are discordant

If the course is unusually chronic, contractures are disproportionate, CK is unexpectedly low or treatment response is poor, reconsider inherited/structural myopathy and other neuromuscular mimics.

Clinical pearl

Distal weakness ≠ IBM.

In established dermatomyositis, proximal + distal weakness with contractures should trigger a careful search for the anti-NXP2 phenotype.

Phenotype first. Antibody in context.

#Dermatomyositis #Myositis #NXP2 #IIM #Rheumatology

[Saravana Kumar🇮🇳 @SaravanakumarOG]

The developmental milestones in infancy- Periyazhwar captures in 10-10 poems

இளம்சொல்லால் உன்னை கூவுகின்றான்- cooing , social smile
ஆடுக செங்கீரை- head control, prop themselves
பட்டிக்கன்றே கொட்டாய் சப்பாணி- sit without support
தளர்நடை-cruising
அம்மனே அப்புச்சி- peak-a-boo.

[Aravind SN @Kidd12Minion]

@SaravanakumarOG My college had 19 people failed in pediatric practical in 2024 and now juniors don’t take the subject very easily and are very sincere in attending postings. Sometimes kuthi vitta thaan message pogum sir 🫡.

[Dr Abhilasha Manwatkar (AIIMS Nagpur) @Abhilasha21822]

At CMC Vellore, we had one of the most renowned immunology labs in the country.😇

Yet ANA blot was NOT available...🥲

Not because it couldn’t be done
but because we were taught something more powerful:😎

“Clinical evaluation first.
Order only what will change your decision.”

At the time, it felt limiting.
Today, I realize it was deliberate training.👩🏾‍🔬🕵🏽‍♀️

Because great clinicians are not made by unlimited panels …
they are made by sharp history, careful examination, and thoughtful questions.👩🏾‍🔧

The lab is an extension of your brain.
It should never become a substitute for it.👩🏾‍🔬

That philosophy from CMC shaped how I practice today.

Bedside before bloodwork.
Thinking before ticking boxes.

#ClinicalMedicine #MedicalEducation #CMC Vellore #Rheumatology #MedTwitter

[Aravind SN @Kidd12Minion]

@SaravanakumarOG Romba azhaga iruku sir 🥹.

[Dr. Datta M.D. (Radiology) building CRASHLab.in @DrDatta_AIIMS]

As a physician-scientist and one of the earliest researchers in India in Arterial Stiffness and Pulse Wave Velocity (2017) which predicts cardiovascular mortality, I can assure you that this device currently has 0 scientific standing as a useful device and do not waste your hard earned money to buy fancy toys billionaires can afford to waste money on. If you are one, then go ahead.

[DocXus @docxusofficial]

𝗙𝗶𝗿𝘀𝘁 𝗙𝗗𝗔-𝗮𝗽𝗽𝗿𝗼𝘃𝗲𝗱 𝗕𝗹𝗼𝗼𝗱 𝗧𝗲𝘀𝘁 𝗳𝗼𝗿 𝗘𝗮𝗿𝗹𝘆 𝗔𝗹𝘇𝗵𝗲𝗶𝗺𝗲𝗿’𝘀 𝗗𝗶𝘀𝗲𝗮𝘀𝗲

Early Alzheimer’s disease can now be evaluated using a simple blood test, reducing dependence on invasive or expensive investigations.

The 𝗟𝘂𝗺𝗶𝗽𝘂𝗹𝘀𝗲 𝗚 𝗽𝗧𝗮𝘂𝟮𝟭𝟳/β-𝗔𝗺𝘆𝗹𝗼𝗶𝗱 𝟭–𝟰𝟮 𝗣𝗹𝗮𝘀𝗺𝗮 𝗥𝗮𝘁𝗶𝗼 is the first 𝗙𝗗𝗔-𝗮𝗽𝗽𝗿𝗼𝘃𝗲𝗱 blood-based assay designed to detect amyloid pathology in adults ≥ 𝟱𝟬 years presenting with cognitive impairment.

𝗪𝗵𝘆 𝘁𝗵𝗶𝘀 𝘁𝗲𝘀𝘁 𝗺𝗮𝘁𝘁𝗲𝗿𝘀:

- Less invasive than 𝗖𝗦𝗙 biomarkers

- More cost-effective than amyloid 𝗣𝗘𝗧 imaging

- Enables earlier diagnostic stratification in routine clinical practice

𝗧𝗲𝘀𝘁 𝗽𝗿𝗶𝗻𝗰𝗶𝗽𝗹𝗲:

- Plasma 𝗽𝗧𝗮𝘂𝟮𝟭𝟳 and β-𝗔𝗺𝘆𝗹𝗼𝗶𝗱 𝟭–𝟰𝟮 are quantified using a two-step chemiluminescent enzyme immunoassay (𝗖𝗟𝗘𝗜𝗔)

- The assay is performed on the 𝗟𝘂𝗺𝗶𝗽𝘂𝗹𝘀𝗲 𝗚 system

- Results are expressed as a numerical ratio ranging from 𝟬.𝟬𝟬𝟬𝟬𝟬 to 𝟭.𝟬𝟬𝟬𝟬𝟬 and interpreted using validated cut-offs

𝗥𝗲𝘀𝘂𝗹𝘁 𝗶𝗻𝘁𝗲𝗿𝗽𝗿𝗲𝘁𝗮𝘁𝗶𝗼𝗻:

- 𝗡𝗲𝗴𝗮𝘁𝗶𝘃𝗲: ≤ 0.00370

- 𝗣𝗼𝘀𝗶𝘁𝗶𝘃𝗲: ≥ 0.00738

- 𝗜𝗻𝗱𝗲𝘁𝗲𝗿𝗺𝗶𝗻𝗮𝘁𝗲: 0.00371 – 0.00737

𝗖𝗹𝗶𝗻𝗶𝗰𝗮𝗹 𝗶𝗻𝘁𝗲𝗿𝗽𝗿𝗲𝘁𝗮𝘁𝗶𝗼𝗻:

- 𝗡𝗲𝗴𝗮𝘁𝗶𝘃𝗲 result: Amyloid pathology unlikely → evaluate non-Alzheimer’s causes of cognitive decline

- 𝗜𝗻𝗱𝗲𝘁𝗲𝗿𝗺𝗶𝗻𝗮𝘁𝗲 result: Additional confirmatory testing required (𝗖𝗦𝗙 biomarkers or amyloid 𝗣𝗘𝗧)

[Priestlyclass Strongman (Redemption Arc) @priestlyclass]

>be ancient Indian king Bhartrihari
>rule Ujjain, got palaces, gold, hundreds of concubines, everything
>life is basically non-stop feasts
>write some fire erotic poetry on the side, Shringara Shataka
>one day, yogi gives him a magic fruit of immortality
>tfw eternal life secured
>think "this for my queen, she deserves it"
>give fruit to queen
>queen secretly hates his him or whatever
>gives it to her lover, some random horse groomer
>groomer thinks "immortality? nah"
>he gives it to his side chick, a courtesan
>courtesan? obsessed with him
>brings fruit back to palace as gift for king
>mfw the fruit of immortality does full circle back to me
>realize everyone in love chain is simping for someone who doesn't care
>queen doesn't love me, lover doesn't love queen, courtesan loves me but lol no
>this is all worldly pleasure and maya
>suddenly vairagya hits
>renounce throne, give kingdom to brother Vikramaditya
>shave head, become yogi
>stoped writing lust poetry and started living in cave near Ujjain
>start dropping truth nvkes on detachment(Vairagya) & wrote deep philosophy
>realize Vairagya Shataka slaps harder than my old love poems(Shringara Shataka)
>finally achieve real peace
>becomes one of the greatest Sanskrit poet-philosophers of classical India

[Ritika Tuli @RitikaTuliMD]

#CardioNugget

Why is procainamide the drug of choice for WPW + AF?

In WPW, the AV node is the “brake”.
If an accessory pathway conducts fast, those impulses can bypass the AV node → very rapid, wide, irregular ventricular rates → may degenerate to VF.

That’s why AV nodal blockers (BB/CCB/digoxin/adenosine) can be dangerous here: they remove the AV nodal brake without fixing the bypass tract.

#EPpeeps #CardioNuggets #MedEd #CardioTwitter

[INSV Kaundinya @INSVKaundinya]

Flag Off Ceremony of Indian Naval Sailing Vessel Kaundinya is the milestone event that marks commencement of its maiden transoceanic voyage from Porbandar, #Gujarat to #Oman.

Watch LIVE as #IndianNavy Flags Off INSV Kaundinya

🗓 29 December 2025 | ⏰ 1230 h

📍 Coast Guard Jetty, #Porbandar

👤 Chief Guest: Vice Admiral Krishna Swaminathan, Flag Officer Commanding-in-Chief, Western Naval Command

👤 Guest of Honour: His Excellency Issa Saleh Abdullah Saleh Al Shibani, Ambassador, Embassy of the Sultanate of Oman

🔗YouTube ▶️: https://t.co/S4hGYAwZg1

🔗Facebook ▶️: https://t.co/nGQS8IiU5h

A unique convergence of cultural diplomacy, maritime heritage revival and #India's historical engagement within the Indian Ocean Region #IOR.

#INSVKaundinya
#MaritimeHeritage
#StitchedShip_India

@MinOfCultureGoI
@SpokespersonMoD
@Indemb_Muscat
@sanjeevsanyal
@indiannavy
@IN_WNC
@IN_HQENC
@IN_HQSNC